An aqueous solution for intraoral cleaning via irradiation with ultraviolet ray and/or near-ultraviolet visible ray and/or ray in an 800-900 nm near-infrared region is employed as the hydrogen peroxide aqueous solution, wherein a concentration of hydrogen peroxide is 1 w/v % to 7 w/v %, and a concentration of a hydrogen peroxide stabilizer is 81 ppm (mg/L) or less in the aqueous solution.

A composition and method directed to the treatment of sun exposed skin, wounds and microbial infections is provided.

A composition and method directed to the treatment of sun exposed skin, wounds and microbial infections is provided.

The invention provides compounds of formula (I) or (II) and tautomers and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula (I) or (II) or a tautomer or salt thereof, methods of making a compound of formula (I) or (II) or a tautomer or salt thereof, and methods of using a compound of formula (I) or (II) or a tautomer or salt thereof as, e.g., inhibitors of bacterial RNA polymerase or as antibacterial agents. ##STR00001##

This invention relates to oral care compositions comprising an effective amount of a basic amino acid in free or salt form, together with an antibacterial agent, and to methods of using and of making such compositions.

Compositions containing quaternary compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, and the composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Also, ophthalmic oil-in-water emulsions containing such compositions, the ophthalmic emulsions being useful for eye care or for the treatment of eye conditions.

Disclosed herein are compositions useful for the treatment and/or prevention of various skin conditions, including infections, via external and/or topical administration to a patient. The compositions comprise an effective amount of a halo active aromatic sulfonamide compound having the structure of Formula (I):

##STR00001##

wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and R.sub.5, X, and M are defined herein. The compositions described may be used to treat and/or prevent a variety of skin conditions, including acne, eczema, rosacea, hives, psoriasis, athlete's foot, candidiasis, shingles, chicken pox, cold sores, bacterial infections, viral infections, fungal infections, and the like. The compositions can be externally and/or topically administered to a patient, for example, as a spray or a wipe. Further, the compositions can also be externally and/or topically administered to a patient by, for example, applying the composition to a medical device that is then implanted into the patient or contacted with the patient.

Disclosed herein are compositions useful for the treatment and/or prevention of various skin conditions, including infections, via external and/or topical administration to a patient. The compositions comprise an effective amount of a halo active aromatic sulfonamide compound having the structure of Formula (I):

##STR00001##

wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and R.sub.5, X, and M are defined herein. The compositions described may be used to treat and/or prevent a variety of skin conditions, including acne, eczema, rosacea, hives, psoriasis, athlete's foot, candidiasis, shingles, chicken pox, cold sores, bacterial infections, viral infections, fungal infections, and the like. The compositions can be externally and/or topically administered to a patient, for example, as a spray or a wipe. Further, the compositions can also be externally and/or topically administered to a patient by, for example, applying the composition to a medical device that is then implanted into the patient or contacted with the patient.

An antimicrobial composition includes an aqueous carrier and a surfactant system. The surfactant system includes a first surfactant including a first polyethylene glycol (PEG) compound with an HLB value of greater than about 10 and less than about 14, and a second surfactant different from the first surfactant, wherein the second surfactant has an HLB value less than about 10.

An antimicrobial composition includes an aqueous carrier and a surfactant system. The surfactant system includes a first surfactant including a first polyethylene glycol (PEG) compound with an HLB value of greater than about 10 and less than about 14, and a second surfactant different from the first surfactant, wherein the second surfactant has an HLB value less than about 10.