Compositions and methods useful in the reduction of localized fat deposits and tightening of loose skin in subjects in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergent compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy and fat deposits associated with cellulite and do not require surgical procedures such as liposuction.

The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.

The invention provides fused heterocyclic organic compounds such as dihydropyrazolopyridotriazinones, compositions containing such compounds, medical kits, and methods for using such compounds and compositions for body contouring and/or reduction of fat in a subject.

Disclosed is a self-reversible reverse latex including: a) 25-80% by mass of a cross-linked anionic polyelectrolyte (P), resulting from the polymerization, for 100 mole percent: i)of a molar proportion 30% and 95% of monomeric units from at least one monomer including a free, partially- or totally-salified strong acid function; and ii)of a molar proportion >0% and 5% of at least one monomer with diethylenic or polyethylenic cross-linking; b) 0.5-10% by mass of a terpolymer of stearyl methacrylate, pentacosaethoxylated behenyl methacrylate and N,N-dimethylacrylamide, resulting from the polymerization, for 100 mole percent: of 80-95 mole percent of stearyl methacrylate, of 2.5-10 mole percent of N,N-dimethylacrylamide, and of 2.5-10 mole percent of pentacosaethoxylated behenyl methacrylate, c) 5-40% by mass of at least one oil, and d) 0.1-40% by mass of water; method of preparing same and use thereof as a thickener.

Peptides that stimulate subcutaneous adipogenesis in mammals and uses thereof are provided.

Peptides that stimulate subcutaneous adipogenesis in mammals and uses thereof are provided.

The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.

The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.

According to an exemplary embodiment, a method and system of non-surgical, non-invasive body contouring and weight reduction treatments may be shown and described. These treatments may provide tissue remodeling, such as skin tightening and skin contour smoothening, as well as provide other cosmetic applications. The method and system may include determining an area of tissue suitable for a noninvasive cosmetic treatment, targeting the area with radiant energy, providing cellulite cream to the targeted area, and massaging the area with a vibrational plate. The system and method may result in the reduction of undesired fat deposits and correction of other skin conditions, such as loose skin and cellulite. Furthermore, all aspects of the present method and system may be performed in a non-invasive manner.

According to an exemplary embodiment, a method and system of non-surgical, non-invasive body contouring and weight reduction treatments may be shown and described. These treatments may provide tissue remodeling, such as skin tightening and skin contour smoothening, as well as provide other cosmetic applications. The method and system may include determining an area of tissue suitable for a noninvasive cosmetic treatment, targeting the area with radiant energy, providing cellulite cream to the targeted area, and massaging the area with a vibrational plate. The system and method may result in the reduction of undesired fat deposits and correction of other skin conditions, such as loose skin and cellulite. Furthermore, all aspects of the present method and system may be performed in a non-invasive manner.