Compositions and methods of using these compositions that can include a targeting moiety and a therapeutic agent are described herein. These compositions can be used for diagnosing and/or treating flaviviridaefamily viruses including Zika virus, dengue virus, and yellow fever.

The present disclosure relates to a polymer in which bovine serum albumin (BSA) is conjugated to a polysaccharide, a method of preparing the same, an enzyme-stabilizing composition including the same, and a method of amplifying or detecting a target nucleic acid molecule in a biological sample by using the same. The polymer is used to prevent the hydrolysis, oxidation, or reduction of an enzyme, such as a nucleic acid polymerase, in a composition, thereby maintaining the stability of the composition. Even when stored at room temperature and high temperature, a composition including the polymer can stably maintain enzymatic activity equivalent to that of a composition kept frozen. Accordingly, the polymer of the present disclosure and a composition including the same efficiently detect a target nucleic acid molecule associated with the onset of infectious diseases and/or cancer, and thus can be usefully applied to the diagnosis of diseases.

The present invention relates to a method of preparing a hierarchically porous polymer and a hierarchically porous polymer prepared thereby. The method comprises the steps of: (a) polymerizing an external oil phase of a high internal phase emulsion (HIPE) consisting aqueous droplets to produce a cross-linked block copolymer; (b) obtaining a macroporous polymer with interconnected macropores by removing the aqueous droplets; and (c) treating the obtained porous polymer with a base, thereby obtaining a hierarchically porous polymer having three-dimensional mesopores formed in the macroporous walls. According to the method, the macropore size and mesopore size of the hierarchically porous polymer can all be controlled. The hierarchically porous polymer prepared by the method can easily separate polymers having different sizes, and thus is highly useful in the polymer separation field.

The invention relates to an iron oligosaccharide compound with improved stability comprising a hydrogenated oligosaccharide in stable association with ferric oxyhydroxide, the content of dimes saccharide in said hydrogenated oligosaccharide being 2.9% by weight or less, based on the total weight of the hydrogenated oligosaccharide. In further aspects is provided a CD process for preparing said compound as well as the use of said compound for preparation of a composition for treatment of iron deficiency anaemia.

Amine modified dextran is labeled with mannose molecules as well as tin-117m. This tin-117m labeled mannose modified dextran is useful in treating maladies that express CD206, in particular rheumatoid arthritis, as well as the cancer typically located in the lymph nodes. This provides a systemic treatment for such maladies. The tin-117m will destroy cells to which it is bonded and also can be imaged. Further, due to the nature of the radiation from the tin-117m, it does not do significant damage to nearby healthy cells.

Describes cooperative hybrid complexes of hyaluronic acid, a simple and economical method for production thereof and use thereof in the area of medicine, cosmetics and food.

A process for the preparation of nanoparticles from polysaccharides and derivatives thereof, by their specific partial oxidation to produce aldehyde groups and attachment of compounds with amino or other group with the RNH2 bond which react with aldehyde groups, and a nanoparticle produced by such process.

Compositions are disclosed herein comprising poly alpha-1,3-1,6-glucan with a weight average degree of polymerization (DP.sub.w) of at least 1000. This glucan polymer comprises at least 30% alpha-1,3 linkages and at least 30% alpha-1,6 linkages. Further disclosed are glucosyltransferase enzymes that synthesize poly alpha-1,3-1,6-glucan. Ether derivatives of poly alpha-1,3-1,6-glucan and methods of using such derivatives as viscosity modifiers are also disclosed.

The present inventions relates to beads as biocompatible material adapted for use within the human or animal body. Said beads arc highly useful for tissue engineering, in situ tissue regeneration, as well as for drug and/or cells delivery. In addition, said beads may support biotechnological applications such as cell carriers.

Compositions are disclosed herein comprising a graft copolymer having (i) a backbone comprising dextran with a molecular weight of at least about 100000 Daltons, and poly alpha-1,3-glucan side chains comprising at least about 95% alpha-1,3-glucosidic linkages. Further disclosed are reactions for producing such graft copolymers, as well as their use in absorbent materials.