A neural probe structure includes a probe which is inserted into a living body, and a magnetic field inductor which is formed in the probe, wherein when a power source is supplied, the magnetic field inductor generates a magnetic field and applies magnetic stimulation to a target site of the living body into which the probe is inserted. A method for manufacturing the neural probe structure includes forming a first pattern on a first substrate and filling the first pattern with a conductor, stacking a second substrate on the first substrate, and forming a second pattern connected to the first pattern on the second substrate and filling the second pattern with a conductor, wherein the first substrate and the second substrate form the probe, and the conductor of the first pattern and the conductor of the second pattern form the magnetic field inductor.

Wearable systems and methods to comprehensively analyze physical activity of a user for training and/or therapeutic purposes, by analyzing multiple channels of data about both muscle activity, using non-invasive surface electromyography (sEMG), and associated motion from that muscle activity, using inertial measurement units (IMU), are disclosed.

Neurophysiological instruments and techniques are improved through various enhancements. Stimulation of an instrument is possible while it is advancing into the spine or elsewhere, alerting the surgeon to the first sign the instrument or device (screw) may be too near a nerve. A directional probe helps surgeons determine the location of the hole in the pedicle. Electrically insulating sleeves prevent shunting into the soft tissues. According to a different improvement, the same probe to be used to stimulate different devices, such as screws and wires. Electrical impulses may be recorded from non-muscle regions of the body, including the spine and other portions of the central nervous system as opposed to just the extremities.

Ruptured Abdominal Aortic Aneurysms (AAA) cause a large number of deaths annually. Ruptures occur even in people who are already diagnosed with AAA and are being monitored. The reason is that the interval between tests is too long because of the need to visit a pathological facility with imaging equipment. It is preferable to estimate the progress of AAA frequently, once detected, in a non-invasive manner, preferably at the subject's home, without the need for the subject to visit a pathological facility. A device is disclosed for detecting a state of a vascular pathology of a subject, comprising a sensor signal unit (103) for providing a signal representative of a blood volume in a body part of a subject, a comparator (107) for comparing the sensor signal with a reference signal, and a user interface (109) for conveying a result based on the comparison to a user of the device.

A renal denervation feedback method is described that performs a baseline measurement of renal nerve plexus electrical activity at a renal vessel; denervates at least some tissue proximate the renal vessel after performing the baseline measurement; performs a post-denervation measurement of renal nerve plexus electrical activity at the renal vessel, after the denervating; and assesses denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel.

In certain embodiments, a neural probe comprises a substrate comprising elongated shanks for penetrating neural tissue, each comprising a proximal end and a distal end; at least one optical source integral to the neural probe for illuminating the neural tissue; and microelectrodes located proximate the distal end of the elongated shanks for monitoring neuronal activity. In certain embodiments, a method of monitoring neuronal activity comprises implanting the neural probe into a test subject such that the elongated shanks protrude into neural tissue of the test subject; illuminating the neural tissue with the at least one optical source; and measuring neuronal activity in response to illuminating the neural tissue. In certain embodiments, a device comprises a semiconductor chip; at least one optical source integral to the semiconductor chip; and sensor elements integral to the semiconductor chip for collecting data responsive to light emitted from the at least one optical source.

A physiological signal processing system for a physiological waveform that includes a cardiovascular signal component provides a variable high pass filter that is responsive to the physiological waveform, and that is configured to high pass filter the physiological waveform in response to a corner frequency that is applied. A heart rate metric extractor is responsive to the variable high pass filter and is configured to extract a heart rate metric from the physiological waveform that is high pass filtered. A corner frequency adjuster is responsive to the heart rate metric extractor and is configured to determine the corner frequency that is applied to the variable high pass filter, based on the heart rate metric that was extracted. Analogous methods may also be provided.

A computer-assisted surgery system may have a robotic arm including a surgical tool and a processor communicatively connected to the robotic arm. The processor may be configured to receive, from a neural monitor, a signal indicative of a distance between the surgical tool and a portion of a patient's anatomy including nervous tissue. The processor may be further configured to generate a command for altering a degree to which the robotic arm resists movement based on the signal received from the neural monitor; and send the command to the robotic arm.

A method and system capable of identifying ectopic foci, rotors, or conduction pathways involved in reentrant arrhythmias within cardiac tissue, and then treating identified ectopic foci, rotors, and/or pathways with either lethal or sub-lethal temperatures. The system includes a medical device having one or more mapping elements and one or more treatment elements, and a computer programmable to identify ectopic foci and rotors based at least in part on signals received from the one or more mapping elements at one or more locations.

The present invention relates generally to an ophthalmic device capable of monitoring neural frequencies and correlating the measured frequencies them to specific brain activity/functions. In some embodiments, profiles specific to the user of the ophthalmic device can be pre-programmed to tailor a brain activity/function profiles according to a user. Based on the determined brain activity/function from the correlation, a signal may be generated to provide feedback to the user. The signal may be transmitted to the user in one or more form. For example, the signal may be outputted to a wireless device in wireless communication with the ophthalmic device, and/or through an audible signal projected by an acoustic element, and/or a visual signal projected using a photon emitter, both which may be included in the ophthalmic device.