The present disclosure describes system and methods for detecting and amplifying weak magnetic fields generated by anatomical structures. The disclosure describes an implantable magnetic reporter system. The magnetic reporter system includes a magnetic reporter. The magnetic reporter includes a platform coupled to a support structure by a plurality of torsional flexures. A magnet is disposed on the platform, and the magnet and platform rotate when exposed to a magnetic field. The rotation of the magnet generates a stronger magnet field that is detectable external to the patient.

A method of extracting complex impedance from selected volumes of the material under test (MUT) combined with various embodiments of electrode sensor arrays. Configurations of linear and planar electrode arrays provide measured data of complex impedance of selected volumes, or voxels, of the MUT, which then can be used to extract the impedance of selected sub-volumes or sub-voxels of the MUT through application of circuit theory. The complex impedance characteristics of the sub-voxels may be used to identify variations in the properties of the various sub-voxels of the MUT, or be correlated to physical properties of the MUT using electromagnetic impedance tomography and/or spectroscopy.

The disclosure herein provides cardiac monitoring and diagnostic system, methods, and devices. A cardiac diagnostic system for detecting potential indicators of cardiac disease comprises: a cardiac monitoring device comprising at least one electrode configured to detect an analog electrical cardiac signal of a user; a cardiac signal filter configured to convert the analog electrical cardiac signal to digital electrocardiogram data; an atypical cardiac sequence detector configured to detect atypical cardiac patterns in the electrocardiogram data that are potentially indicative of cardiac disease; and a notification transmitter configured to generate an alert when a detected atypical cardiac pattern is determined to be indicative of cardiac disease.

Certain examples provide systems and methods to enhance slow wave sleep. An example method includes identifying a sleep stage for slow wave sleep in a subject being monitored. The example method also includes generating, following identification of slow wave sleep and using a processor including a phase locked loop, an output signal based on a phase of a reference input signal, the output signal phase locked according to the reference input signal. The example method includes delivering, during slow wave sleep for the subject, a stimulus to the subject based on the phase locked output signal. The delivering includes providing the stimulus in a series of signal pulses for a first period of time; and providing a refractory period without pulses in a second period of time. The method further includes measuring feedback from the stimulus.

The invention relates to a method and a magnetoencephalography (MEG) measurement device. In the method there is determined the ending of a scheduled inactivity period of the MEG device. At the ending of the inactivity period a cryocooler of the MEG device is switched off. Helium is allowed to boil in the Dewar vessel of the MEG device when the MEG device is active and used to perform patient measurements. The boiled helium is collected via a compressor to an external storage tank. When a new inactivity period for the MEG device commences, the cryocooler is started anew and helium is let from the external storage tank in-to the Dewar vessel, where it is re-liquefied by the cryocooler. The compressor may be switched off when the cryocooler is switched on.

An electrocardiography (ECG) physiological monitoring system that includes an ECG sensor assembly having first and second capacitive electrodes that are configured to electrically couple to a subject's skin and detect ECG signals, a reference electrode that is configured to average the capacitance potential of the first and second electrodes, an electronics module that is in direct communication with the ECG sensor assembly and programmed to control the ECG sensor assembly, process ECG signals therefrom, and wirelessly transmit the processed ECG signals, and transmission conductors that are configured to provide a signal communication path between the electronics module and the ECG sensor assembly.

An electrocardiography (ECG) physiological monitoring system including an ECG sensor assembly further having at least a first capacitive electrode fabric layer configured to electrically couple to the subject's skin and detect ECG signals, a second reference electrode fabric layer that is configured to shield the first capacitive electrode fabric layer from electromagnetic interference, an electronics module that is in direct communication with the ECG sensor assembly and programmed to control the ECG sensor assembly, process ECG signals therefrom, and wirelessly transmit the processed ECG signals, and transmission conductors that are configured to provide a signal communication path between the electronics module and the ECG sensor assembly.

A lightweight, disposable and substantially radiolucent electrode or sensor assembly for that universally connects to separate, non-integrated electrodes or sensors for the monitoring of the physiological parameters of a live subject wherein the electrode assembly is comprised of one or more radiolucent electrical connectors for connecting the electrode assembly to the sensors. The present invention also discloses a method of positioning the electrode assembly on a patient whose physiological signs are being monitored such that access to the patient's chest is substantially unimpeded so as not to obstruct the electromagnetic imaging of the patient's chest, the application of defibrillation paddles or surgical procedures that require access to the chest area.

A method and medical device for determining sensing vectors that includes sensing cardiac signals from a plurality of electrodes, the plurality of electrodes forming a plurality of sensing vectors, setting a blanking period and a blanking period adjustment window for the plurality of sensing vectors in response to the sensed cardiac signals, determining first signal differences during the blanking period adjustment window, and adjusting the blanking period in response to the determined first signal differences.

Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of identifying an activation time in a cardiac electrical signal. The method may include sensing a cardiac electrical signal, generating an approximation signal based at least in part on one or more parameters of the cardiac electrical signal, identifying a fiducial point on the approximation signal and determining, based at least in part on a timing of the fiducial point in the approximation signal, an activation time in the cardiac electrical signal.