Systems and methods are described for detecting and characterizing seizures or seizure-related events. The methods herein may include determining magnitude and/or scaled magnitude data for each of at least one high and low frequency group of signals. Based on the determined magnitudes and/or scaled magnitude data, seizures or seizure-related events may be characterized.

A biological recording device used to monitor biological electrical activity and a method of recording neural signals. In a preferred embodiment, the biological recording device is a neural probe. The biological recording device includes a probe body with a probe shank and a recording platform that uses a delta (Δ) modulator and a delta sigma analog to digital converter (ΔΣ ADC). The Δ modulator and the ΔΣ ADC form a Δ-ΔΣ analog front end (AFE) architecture for processing biological electrical activity. A large dynamic range (DR) of neural signals, including local field potentials (LFPs) and action potentials (APs) for example, can be compressed and subsequently reconstructed.

A medical alarm communications system comprises a pager like device to be kept near a patient. The pager like device communicates medical alerts regarding the patient to a remote central station, which can provide therapeutic and/or diagnostic assistance by communicating to the pager like device. When the pager like device determines that an alert should be sent to the central station, it attempts to establish communication with the central station according to a primary communication protocol. If this attempt is unsuccessful according to some predetermined criteria (e.g. too much time has elapsed before communication is established), then the pager like device generates a message to the patient indicative of the failure, and The attempts to establish communication with the central station according to a secondary communication protocol.

Seizure prediction systems and methods include measuring impedance within a brain of a patient to determine whether the brain is in a state indicative of a possibility of an onset of a seizure. In some embodiments, the measured impedance is compared to a predetermined threshold in order to determine whether the brain is in a state indicative of a possibility of a seizure. In other embodiments, a trend of the impedance measurements is correlated to a template. In other embodiments, a frequency component of a waveform of the impedance measurement amplitudes over time is correlated to frequency components of a template waveform. Upon detecting a state in which a seizure is likely to occur, a seizure indicator may be generated, which, in some embodiments, may be used to activate therapy delivery to the patient or, in other embodiments, activate an alarm.

A patient advisory device (“PAD”) and its methods of use. The PAD may be configured to alert the patient about an estimated brain state of the patient. In preferred embodiments, the PAD is adapted to alert the patient of the patient's brain state, which corresponds to the patient's propensity of transitioning into an ictal brain state, e.g., having a seizure. Based on the specific type of alert, the patient will be made aware whether they are highly unlikely to have a seizure for a given period of time, an elevated propensity of having a seizure, a seizure is occurring or imminent, or the patient's brain state is unknown.

A biological signal measuring equipment used in a measurement of a biological signal in a head portion, has a jaw contact portion that comes into contact with a forehead; an occiput contact portion that comes into contact with an occiput; and a supporter that is interposed in a front and rear direction of the head portion and is supported by the head portion by using the jaw contact portion and the occiput contact portion as ends. The biological signal measuring equipment performs the measurement in the same manner as the case of measuring a wave motion of a short period, even in the case of measuring the wave motion of a long period generated in a head portion.

A physiological signal of a patient is sensed with sense electrodes symmetrically arranged relative to a stimulation electrode. In some examples, a member includes a plurality of relatively small electrodes that are configured to function as both sense and stimulation electrodes. One or more of the electrodes may be selected as stimulation electrodes and two or more different electrodes of the member may be selected as sense electrodes that are symmetrically arranged relative to the one or more selected stimulation electrodes. In some examples, a member includes a plurality of levels of segmented sense electrodes and a plurality of levels of stimulation electrodes. The levels of sense electrodes are arranged such that each level of stimulation electrodes is adjacent at least two levels of sense electrodes symmetrically arranged relative to the level of stimulation electrodes.

A neural interface includes a first dielectric material having at least one first opening for a first electrical conducting material, a first electrical conducting material in the first opening, and at least one first interconnection trace electrical conducting material connected to the first electrical conducting material. A stiffening shank material is located adjacent the first dielectric material, the first electrical conducting material, and the first interconnection trace electrical conducting material.

Methods and systems for monitoring a driver of a vehicle using a driver state monitoring (DSM) system. The DSM system includes a sensing unit that senses biological information of a user of a vehicle. The DSM system also includes a controller that determines a drowsy state of the user based on the sensed biological information. The controller also determines a current condition of traffic and outputs information recommending rest for the user based on the determined drowsy state of the user and the determined current condition of traffic. The controller monitors the traffic and determines a rest state of the user, and outputs an alarm based on monitoring the traffic and the determined rest state of the user.

Implantable systems and methods directed toward improved accuracy in cardiac signal analysis. An impedance waveform is captured and used to confirm the analysis performed by the system on electrical signals or electrocardiogram. A detected heart beat from the electrocardiogram is either confirmed or identified as a misdetection depending on whether the impedance waveform shows likely correct or incorrect detection. Identified misdetection can then be corrected or otherwise mitigated.