A mutually calibrated magnetic imaging array system is described. The system includes a non-target magnetic source rigidly attached to a magnetometer, and an attached control unit to measure and adjust several parameters of a magnetic imaging array. A non-target magnetic field source is used to generate a well-defined and distinguishable spatial magnetic field distribution. The source is rigidly attached directly to a magnetometer, while the relative positions of the magnetometers are unknown. The magnetic imaging array is used to measure the strength of the non-target source magnetic fields and the information is used to calibrate several parameters of the array, such as, but not limited to, effective magnetometer positions and orientations with respect to each other and cross-talk between the magnetometers. The system, and method described herein eliminates the need for a separate calibration phantom.

A wireless system for a person includes a wearable appliance with an accelerometer; a wireless device in communication with the wearable appliance; and a remote computer coupled to the wireless device to provide information to an authorized remote user.

Methods and apparatuses, including devices and systems, for remote and detection and/or diagnosis of acute myocardial infarction (AMI). In particular, described herein are handheld devices having an electrode configuration capable of recording three orthogonal ECG lead signals in an orientation-specific manner, and transmitting these signals to a processor. The processor may be remote or local, and it may automatically or semi-automatically detect AMI, atrial fibrillation or other heart disorders based on the analyses of the deviation of the recorded 3 cardiac signals with respect to previously stored baseline recordings.

Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

A neural-interface probe is provided. The probe may comprise a chip, a wire bundle substrate, and an encapsulant material. The chip may comprise a plurality of bond pads. The wire bundle substrate may comprise a plurality of wires extending through the substrate. The plurality of wires may comprise: (1) a proximal portion connected to the plurality of bond pads to thereby couple the chip to the substrate, and (2) a flexible distal portion configured to interface with neural matter. The encapsulant material may be disposed at least between the chip and the wire bundle substrate.

A portable monitoring device comprises a hearing aid having a housing, a microphone (24), an acoustic signal processing means (43), and an acoustic output transducer (33). The portable monitoring device further comprises an EEG monitoring system arranged at least partly in said housing, and comprising a measuring unit (3) having electrodes (12) arranged external to the housing. The EEG monitoring system comprises a processing unit (42) for analyzing the EEG signal for identifying or predicting specific biological incidences, such as a seizure, in said person, decision means for deciding, based on said analyzed EEG signal, when an alarm or information must be provided to said person, and means for providing said alarm or information through said output transducer (33). The invention further provides a method of monitoring an EEG signal of a hearing impaired person.

A textile substrate with a measuring sensor for measuring a physiological signal. The textile substrate has integrated irremovably therewith a base structure component for electronics, such as for example a plastic base for a transmitter for attaching the transmitter and other electronics to the substrate irremovably by way of said base structure component. In addition, signal transfer elements from the measuring sensor are adapted to extend in a watertight manner to the electronics through said base structure component integrated irremovably with the textile substrate.

A disposable self-powered biomedical sensor comprises a printed wet electrode on a substrate sheet. The wet electrode is provided with an electrolyte element to enhance the electrical contact with a surface to be measured. Moreover, a printed battery encapsulated in a hermetically sealed compartment is provided on the substrate sheet. The disposable self-powered sensor can be stored within an enclosure or a package which provides a proper atmosphere to prevent the drying of the electrolyte and prolong the shelf life of the sensors.

System for detecting the level of discomfort of aquatic animals during experimental studies, with a water tank, a reference electrode placed at one of the sides of the tank, at least one recording electrode placed at another side of the tank, a bio amplifier for amplifying a received bio-signal at the recording electrode, a microprocessor for treating the signals and a low-pass filter for filtering the signals received. The system can provide a precise, quantifiable and specific indication of the level of stress/wellbeing of aquatic animals in normal living conditions as well as in experimental conditions without interfering with the animals' life.

An optical electrode having a plurality of electrodes, including a recording electrode having a roughened surface and an optical light source configured to emit light, wherein at least a portion of the light impinges on the recording electrode. Also disclosed are methods of producing an optical electrode and an opto-electronic neural interface system.