Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

The present invention provides a stretchable laminate sheet for a garment for measuring biological information. The stretchable laminate sheet has favorable conductivity and stretchability, and has such an enhanced adhesiveness to a substrate as to prevent peeling and disconnection of an electrode that are caused by stress and deformation when the garment is put on, taken off, and washed, while detecting a stable electrical signal. The stretchable laminate sheet of the present invention at least includes a stretchable insulating layer having adhesiveness and a stretchable conductor layer. The stretchable laminate sheet has a 90 degree peel strength between the stretchable insulating layer and the adherend layer of 1.0 N/cm or more.

A pixel circuit includes a sensing block, a stimulation block, a first line control circuit, and a second line control circuit. The sensing block outputs biometric data of a biosignal in response to a first selection signal. The stimulation block radiates a stimulation signal in response to a second selection signal. The first line control circuit outputs the first selection signal for selecting the sensing block as a target sensing block, and outputs the second selection signal for selecting the stimulation block as a target stimulation block. The second line control circuit processes characteristic data associated with the biometric data and the stimulation signal.

Disclosed are devices, systems, and methods for determining the dipole densities on a cardiac surface using electrodes positioned on a torso of a patient. Electrodes are integrated into a piece of clothing worn by a patient. The clothing serves to fix the position of the electrodes adjacent a patient's torso. Ultrasonic transducers and sensors are used to determine a distance between the epicardial surface and the electrodes and are also used to detect epicardial surface motion as well as epicardial wall thickness.

In one aspect, an apparatus for detecting fatigue comprises a dry-contact electroencephalogram (EEG) electrode to measure EEG data operably coupled to at least one processor. The at least one processor is to: calculate a frequency domain representation of the EEG data, detect spectral features indicative of fatigue based on the frequency domain representation; and determine whether the brain is fatigued based on the detection. In another aspect, a method for detecting fatigue comprises receiving EEG data from dry-contact EEG electrode, calculating a frequency domain representation of the EEG data, detecting spectral features indicative of fatigue based on the frequency domain representation; and determining whether the brain is fatigued based on the detection.

A method and system for assessing a mental fitness state of a person using objective physiologic signals from the person includes arranging one or more sensors in proximity to the person's head to measure at least one electroencephalogram (EEG) signal of the person, and analyzing the at least one EEG signal by computing a power in the EEG signal in an EEG signal band; determining a characteristic of the computed power that, for the EEG signal band, is indicative of an emotional or cognitive state of the person; and assessing a mental fitness state of the person based on the determined characteristic. An assessment output is generated which reports the assessed mental fitness state of the person. In at least one implementation, the EEG signal contains oscillating theta waves, and a variance in timing of maximum power occurring in the theta waves around a determined average latency is calculated.

The present invention is directed to a physiological recording device, or other types of sensors to detect a biopotential, and more particularly, a physiological recording electrode that can be used without skin preparation or the use of electrolytic gels. The invention is further directed to the configurations of structures on the physiological recording electrode's lower surface. The structures having a length, width, and height, which are capable, at least in part, of transmitting an electric potential from the skin which can be measured. The structures may or may not limit the depth of application, and/or anchor the electrode or other device during normal application, and/or allow for uniform application of the electrode or other device over unprepared skin.

A method operates a hearing aid for a user. A neuronal signal of the user is measured in the method and a listening effort of the user is determined therefrom. Both an intensity of the listening effort and a hearing direction are determined from the neuronal signal. The intensity and the hearing direction form a hearing vector. A mode of operation of the hearing aid is adapted or set depending on the hearing direction, for the purposes of reducing the intensity of the listening effort.

The present invention is directed to a method of continuously monitoring neuronal avalanches in a subject comprising (a) determining a deviation in avalanche exponent () or branching parameter () from a predetermined value at rest, wherein the pre-determined value of is a slope of a size distribution of the synchronized neuronal activity and the predetermined value is 3/2 and the pre-determined value of is a ratio of successively propagated synchronized neuronal activity and the predetermined value is 1; and (b) repeating step (a) one or more times to continuously monitor neuronal avalanches in a subject. The invention also features methods of determining or monitoring the degree of sleep deprivation in a subject, methods of identifying subjects that are susceptible to a sleep disorder and methods of diagnosing a sleep disorder in a subject.

The disclosure describes a method and system or controlling symptoms of patients suffering from Parkinson's Disease. In some examples, one or more biomarkers indicative of a patient's present symptoms are determined. The biomarkers may be used to control therapy delivered to the patient in a closed-loop manner. In addition, biomarkers may be used as an indication of therapy effectiveness.