The present invention provides a pharmaceutical composition that includes a neutral carrier treated with energy proportional to biopotential of human brain or nervous tissue. Preferably, the neutral carrier is obtained from initial liquid neutral carrier which after the energy treatment is subjected to multiple consecutive dilution combined with external shaking of each dilution in accordance with homeopathic technology. Preferably, the initial liquid carrier is treated with electrical current by passing electricity through at least two electrodes, which current is proportional in amplitude to biopotential of human brain.

A variety of methods of treatment is provided, including methods of treatment of psychosis, depression, attention deficit disorder, and other conditions of central nervous system, including a number of psychiatric conditions.

A device for passing electricity through the neutral liquid carrier is also provided.

A headset for use in delivering electrical stimulation to the skin surface of the head or in sensing one or more parameters of the head of a user.

A brain training system and method are provided that incorporates a first phase and a second phase of brain training. The first phase is designed to increase attention by requiring the completion of an attention-based activity or task. This may require the identification of match or mismatched images. The second phase is designed to increase working memory by requiring the completion of a working memory-based task that requires the repetition of an illumination sequence. Each phase may be implemented in a self-contained handheld device, similar to the shape of a tablet, or may be implemented in a computer application, such as software. The answers of each phase are recorded in a central database and the system may provide recommendations based on the answers.

A biological recording device used to monitor biological electrical activity and a method of recording neural signals. In a preferred embodiment, the biological recording device is a neural probe. The biological recording device includes a probe body with a probe shank and a recording platform that uses a delta (Δ) modulator and a delta sigma analog to digital converter (ΔΣ ADC). The Δ modulator and the ΔΣ ADC form a Δ-ΔΣ analog front end (AFE) architecture for processing biological electrical activity. A large dynamic range (DR) of neural signals, including local field potentials (LFPs) and action potentials (APs) for example, can be compressed and subsequently reconstructed.

A biological signal measurement system includes: a biological signal measurer that measures a biological signal including external noise of biological noise and of environmental noise; biological noise measurer that measures a signal including the biological noise; a biological noise estimator that estimates the biological noise from the signal measured by the biological noise measurer; an environmental noise measurer that measures a signal including the environmental noise; an environmental noise estimator that estimates the environmental noise from the signal measured by the environmental noise measurer; and a calculator that calculates the biological signal in consideration of an effect of the external noise using the signal measured by the biological signal measurer, the biological noise estimated by the biological noise estimator and the environmental noise estimated by the environmental noise estimator.

Seizure prediction systems and methods include measuring impedance within a brain of a patient to determine whether the brain is in a state indicative of a possibility of an onset of a seizure. In some embodiments, the measured impedance is compared to a predetermined threshold in order to determine whether the brain is in a state indicative of a possibility of a seizure. In other embodiments, a trend of the impedance measurements is correlated to a template. In other embodiments, a frequency component of a waveform of the impedance measurement amplitudes over time is correlated to frequency components of a template waveform. Upon detecting a state in which a seizure is likely to occur, a seizure indicator may be generated, which, in some embodiments, may be used to activate therapy delivery to the patient or, in other embodiments, activate an alarm.

A patient advisory device (“PAD”) and its methods of use. The PAD may be configured to alert the patient about an estimated brain state of the patient. In preferred embodiments, the PAD is adapted to alert the patient of the patient's brain state, which corresponds to the patient's propensity of transitioning into an ictal brain state, e.g., having a seizure. Based on the specific type of alert, the patient will be made aware whether they are highly unlikely to have a seizure for a given period of time, an elevated propensity of having a seizure, a seizure is occurring or imminent, or the patient's brain state is unknown.

A biological signal measuring equipment used in a measurement of a biological signal in a head portion, has a jaw contact portion that comes into contact with a forehead; an occiput contact portion that comes into contact with an occiput; and a supporter that is interposed in a front and rear direction of the head portion and is supported by the head portion by using the jaw contact portion and the occiput contact portion as ends. The biological signal measuring equipment performs the measurement in the same manner as the case of measuring a wave motion of a short period, even in the case of measuring the wave motion of a long period generated in a head portion.

A diagnostic headband has an elongated body with two ends. A mechanism couples the two ends with one another. At least one first lead is coupled with the body. At least one second lead extends from the body. The leads couple with lead pads on the user. An electrical harness is coupled with the body. The electrical harness electrically couples with the at least one first and second leads.

A method for storing data of photoelectrically synchronous brain activity recording, said method comprising: generating data when a photoelectrically synchronous brain activity detection system is operating; generating from said data a data storage file comprising a basic information data segment, a near-infrared spectrum data segment and a brain electrical activity data segment, and sequentially storing said data segments into a .neg file in binary form according to the above order. The method can store comprehensive test information, flexibly configure the near-infrared and brain electrical measurement information, and realize synchronous storage of near-infrared data and brain electrical data and maintain file version compatibility.