The present invention relates to a perfusion cannula for placement of an access, having a cannula wall and a perfusion lumen which is surrounded by the cannula wall and in which a fluid flow can flow through the perfusion cannula, wherein the perfusion cannula furthermore comprises at least one sensor lumen and at least one sensor device, in particular an ECG sensor, which is arranged at least partially in the sensor lumen. As a result, it is possible to provide a particularly reliable perfusion cannula with improved functionality and for reliable handling, in particular in conjunction with an extracorporeal lung support system.

One embodiment provides a system for determination and utilization of cardiac electrical asynchrony data. The system includes an analysis circuitry including a processor and a memory, the analysis circuitry configured to: obtain a plurality of sets of cardiac signals collected in at least two locations of a heart of a patient, the signals comprising at least one of surface electrocardiography signals and pseudo-surface ECG signals; detect one or more QRS complexes for each of the sets based on the cardiac signals for that set; obtain one or more cross-correlation signals, each of the cross-correlation signals being between at least two of the signal sets and being obtained using the detected QRS complexes from the signal sets; and calculate one or more asynchrony indices using one or more of the cross-correlation signals, each of the asynchrony indices being indicative of a level of asynchrony between the at least two locations.

A method of generating a cardiac electrophysiology map includes receiving a reference biological signal and an electrical signal indicative of electrical activity at a location on a patient's heart. Using a graphical user interface, a practitioner designates at least two trigger point icons, one upward-pointing and one downward-pointing, on a graphical representation of the reference biological signal (e.g., a waveform). By pairing one upward-pointing icon with one downward-pointing icon, a plurality of triggering criteria are defined. Electrophysiology data points are captured and/or added to the electrophysiology map when the triggering criteria are satisfied.

A catheter assembly including an elongate catheter tube is disclosed. The number of lumens defined by the catheter tube can vary as a function of longitudinal length along the catheter tube. For instance, the catheter tube can define three lumens from the proximal end of the catheter tube and terminate one of the lumens at an intermediate termination point such that only two lumens are defined further distally along the catheter tube. A sensor can be placed in the terminating lumen so as to isolate it from the other lumens and from blood or other body fluids while still enabling the sensor to reside within the patient body when the catheter tube is positioned in the patient for use. In addition to this, various other lumen transition and sensor configurations are disclosed.

A device and method for manufacturing an implantable cardiac monitor device are provided. The method joins a feed-through assembly to a device housing having electronic components therein. The feed-through assembly includes conductors having distal ends connected to the electronic components and has proximal ends projecting from the feed-through assembly. The method assembles a header having a sensing electrode and an antenna embedded within a non-conductive header body. The electrode and antenna includes corresponding interconnection plates. The header body includes a housing mounting surface that includes at least one passage aligned with an interconnect cavity that includes the interconnection plates. The header body further includes a window exposing the interconnect cavity and interconnect regions. The method further directs the proximal ends of the conductors through the passage to align with the interconnect regions and secures the proximal ends and the interconnect regions to one another through the window.

A leadless implantable medical device comprises a first electrode configured to deliver electrical pacing energy, a second electrode configured to sense intrinsic electrical cardiac activity, and a third electrode configurable to both deliver electrical pacing energy and sense intrinsic electrical cardiac activity. The first and third electrodes are used for delivering electrical pacing energy and the second and third electrodes are used to sense intrinsic electrical cardiac activity. None of the first, second and third electrodes are incorporated into a lead.

A contact detection instrument 1 is provided with a rod 12, a tip sensor portion 20 that is attached to one end of the rod 12 and is inserted into a living body through a hole, a speaker 14 that, from outside the living body, inputs a sound into a hollow space that is formed in the interior of the rod 12 and the tip sensor portion 20, and a microphone 15 that, outside the living body, outputs an electrical signal that corresponds to the sound inside the hollow space, with the tip sensor portion 20 including an elastic material that covers the hollow space.

This disclosure is directed to a catheter having an asymmetric basket-shaped electrode assembly at the distal end of the catheter body formed from a plurality of spines with electrodes. The plurality of spines are radially distributed across a first circumferential portion. One or more counter spines are radially distributed across a remaining second circumferential portion. Diagnostic electrodes are arrayed across the spines, while the counter spines may have one or more reference electrodes.

This disclosure is directed to a catheter having a basket-shaped electrode assembly with a high electrode density. The basket-shaped electrode assembly may have a plurality of spines, such as up to twelve, each with a plurality of electrodes, such as up to sixteen. The distal ends of the plurality of spines are joined at a distal hub, all of which are fashioned from a single piece of superelastic material.

This disclosure is directed to a catheter having a basket-shaped electrode assembly with a high electrode density. The basket-shaped electrode assembly may have a plurality of spines, such as up to twelve, each with a plurality of electrodes, such as up to sixteen. The distal ends of the plurality of spines are joined at a distal hub, all of which are fashioned from a single piece of superelastic material.