A system and method for facilitating a cardiac rhythm disorder diagnosis based on subcutaneous cardiac monitoring data with the aid of a digital computer are provided. Cutaneous action potentials of a patient are recorded as electrocardiogram (EGC) data over a set time period using a subcutaneous insertable cardiac monitor. A set of R-wave peaks is identified within the ECG data and an R-R interval plot is constructed. A difference between recording times of successive pairs of the R-wave peaks in the set is determined. A heart rate associated with each difference is also determined. The pairs of the R-wave peaks and associated heart rate are plotted as the R-R interval plot. A diagnosis of cardiac disorder is facilitated based on patterns of the plotted pairs of the R-wave peaks and the associated heart rates in the R-R interval plot.

Methods and apparatuses for stimulation of the vagus nerve to treat inflammation including adjusting the stimulation based on one or more metric sensitive to patient response. The one or more metrics may include heart rate variability, level of T regulatory cells, particularly memory T regulatory cells, temperature, etc. Stimulation may be provided through an implantable microstimulator.

Described herein are methods for determining a target musculoskeletal activity cycle (MSKC) to cardiac cycle (CC) timing relationship. The method may include detecting a signal responsive to a cyclically-varying arterial blood flow at a location on a head of a user; providing a recurrent prompt at a frequency of the heart pump cycle using the signal, such that the signal correlates with a magnitude of blood flow adjacent to the location, and the recurrent prompt is provided to guide the user to time performance of a component of a rhythmic musculoskeletal activity with the recurrent prompt; and guiding the user to adjust a timing of the component of the rhythmic musculoskeletal activity to substantially maximize a magnitude of the signal. In some embodiments, the method further includes generating the recurrent prompt by amplifying the sound generated by the blood flow in or in proximity to an ear of the user.

A system and a method are provided for using a mobile computing system comprising that has a communication connection configured to communicate with an electrocardiographic (ECG) apparatus to acquire ECG signals from the subject through a plurality of ECG leads. The system includes a processor configured to receive the ECG signals through the communications connection and process the ECG signals to estimate at least one of a respiratory rate of the subject, a tidal volume of the subject, or an ischemic index or repolarization alternans of the subject, from the ECG signals. The processor is further configured to generate an alert upon determining at least one of the ischemic index or repolarization alternans is above a threshold value or a change in respiratory rate or tidal volume indicative of an abnormal respiratory event. The system also includes a display configured to display the alert.

A system and method for accelerating confirmation of cardiac arrhythmias is provided. The system includes memory to store specific executable instructions. One or more processors are configured to execute the specific executable instructions for obtaining a far field cardiac activity (CA) data set that includes far field CA signals for a series of beats. The CA data set includes a first CA data subset and a remainder CA data subset. The system analyzes the CA data set for an arrhythmia of interest utilizing a primary detection process having primary criteria. During a first phase of the primary detection process the system analyzes the first CA data subset to determine whether the first CA data subset satisfies at least a portion of the primary criteria. When the first CA data subset satisfies at least the portion of the primary criteria, the system initiates a secondary confirmation process. Parallel and contemporaneous in time the system i) analyzes the first CA data subset utilizing secondary criteria associated with the secondary confirmation process and ii) analyzes the remainder CA data subset utilizing the primary criteria. The system declares the CA data set to exhibit an arrhythmia episode when the first CA data subset satisfies the secondary criteria and the remainder CA data subset satisfies a remainder of the primary criteria.

A system for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer is provided. A download station retrieves cutaneous action potentials of a patient recorded over a time by an ECG device as ECG data. An R-R interval plot of the ECG data includes R-R intervals plotted along an x-axis of the plot and heart rates associated with the R-R intervals plotted along a y-axis. The R-R intervals are calculated as a difference between recording times of successive pairs of R-wave peaks. Each heart rate is associated with each time difference. One or more portions of the R-R intervals are identified in the plot. Each portion of the R-R intervals includes a cardiac event. Report strips are generated and each includes one portion of the R-R intervals and a portion of the ECG data. The report strips are included in a cardiac report for the patient.

A method and device for acquiring at least a part of an x-ray data set with at least one x-ray device. The x-ray data set includes at least one first x-ray image data set and at least one second x-ray image data set acquired separated in time that are to be evaluated together. Both x-ray image data sets show a region of interest of a patient that is subject to heart motion at different phases of a heart cycle. The second x-ray image data set is acquired triggered at a beginning of each heart cycle covered by the acquisition and with an acquisition rate such that the phases of the acquired x-ray image data set match phases of the first x-ray image data set.

Technologies and techniques for detecting and alerting onset Autism Spectrum Disorder (ASD), where a device receives sensor data including heart rate data, accelerometer data and audio data. The device is configured to activate the collection of accelerometer data and extract accelerometer data features comprising frequency components if the heart rate exceeds a first threshold, activate the collection of audio data and extract audio data features comprising frequency components if the heart rate data meets or exceeds a second predetermined threshold, determine if the audio data meets or exceeds a predetermined audio threshold comprising frequency characteristics, and transmit an alert indicating the detection of an onset ASD episode, based on the extracted audio data features, the extracted accelerometer data features and the heart rate data.

A hemodynamic parameter (Hdp) monitoring system for diagnosing a health condition of a patient and for establishing Hdp marker values or Hdp surrogate marker values for purposes of comparison with Hdp values of a patient is provided. An Hdp monitor senses, measures, and records Hdp values exhibited by the patient during a basal or non-exposure period and furthermore Hdp values exhibited by the patient during or after an exposure period during which the patient is exposed to low-energy electromagnetic output signals. An electrically-powered generator is adapted to be actuated to generate said low-energy electromagnetic carrier output signals for exposing or applying to the patient such output signals during said exposure period.

A biometric information presentation system that enables efficient training by obtaining biometric information without giving a subject a sense of discomfort. The biometric information presentation system uses a garment-type biometric information measuring apparatus including at least fabric having a 20% elongation stress of 20 N or less. A garment pressure of the garment-type biometric information measuring apparatus is 0.1 kPa or more and 1.5 kPa or less. A skin contact-type electrode is provided at a portion of the garment-type biometric information measuring apparatus at which a garment pressure is 0.3 kPa or more. The garment-type biometric information measuring apparatus is worn by the subject. From obtained electrocardiographic information is calculated an RRI, an indicator of parasympathetic activity and indicator of sympathetic activity. The biometric information presentation system presents this calculated result on a terminal device and presents an action based upon the result to achieve the efficient training.