A system and method for ECG data classification for use in facilitating diagnosis of cardiac rhythm disorders is provided. ECG data is obtained via an electrocardiography monitor shaped for placement on a patient's chest. The ECG data is divided into segments and noise detection analysis is applied to the ECG data segments. A noise classification or a valid classification is assigned to each segment of the ECG data. At least one ECG data segment assigned the noise classification and that includes ECG data that corresponds with feedback from the patient via the electrocardiography monitor is identified. The ECG data that corresponds with the patient feedback is removed from the identified ECG data segment with the noise classification. The ECG data segments assigned the noise classification are removed from further analysis.

The present invention describes a system and method for continuous monitoring of central (aortic) and peripheral Blood Pressure. The system includes a fully mobile, non-invasive, continuous blood pressure monitoring system that includes one or more Biostrip devices affixed on a user, coupled with an application running on a computing device, which is further connected to a web server in the cloud. The system performs various computations on the Biostrip device, or on the gateway device (Smartphone or Smartwatch), or on the Cloud, and provides the user and authorized third parties with various insights about the blood pressure levels of the user. Further, the system enables the user to receive biofeedback training for controlling hypertension, and schedule online appointments, pay online for such appointments, share data the data securely to obtain insights.

A system and method for the safe delivery of treatment energy to a patient, which includes verification of system integrity before, during, or after the delivery of treatment energy and provides several mechanisms for rapid termination of the delivery of potentially harmful energy to the patient when a fault condition in the device and/or system is identified. The system may include an energy generator having processing circuitry to determine if there is a fault condition in the system and to automatically terminate a delivery of treatment energy when the processing circuitry determines there is a fault condition. The method may generally include performing a series of pre-checks, synchronizing a treatment energy delivery to the proper segment of the heart's depolarization pattern, configuring the system for treatment energy delivery, delivering the treatment energy, and performing post-treatment evaluation.

Methods and systems for use of the Q-wave to R-wave interval to guide placement of a leadless cardiac pacemaker are disclosed. An implant delivery device is equipped with sensing electrodes to sense R-wave onset in a ventricle of a patient's heart to allow placement at a location of last or latest onset of the R-wave. Guidance tools are provided to assist in determination of the Q-wave to R-wave interval during implantation. For a chronic system, a cooperative approach is disclosed in which an implantable medical device and a leadless cardiac pacemaker exchange data to determine Q-wave to R-wave intervals and enhance cardiac resynchronization therapy delivery by the leadless cardiac pacemaker.

Methods and devices adapted for cardiac signal analysis. A method or device has accessible to it more than one approach to cardiac cycle rate analysis and is adapted to monitor sensing signal quality. In response to an apparent reduction in signal quality or other trigger, the method or device checks whether an arrhythmia or an actual drop in signal quality is occurring prior to modifying sensing configurations or parameters.

A system and method for facilitating a cardiac rhythm disorder diagnosis with the aid of a digital computer is provided. Cutaneous action potentials of a patient are recorded over a set period of time as ECG data and a difference between recording times of successive pairs of R-wave peaks are recorded as R-R intervals. A heart rate is associated with each time difference. An R-R interval plot of the ECG data is generated. A presence of a cardiac event is displayed by presenting a presence of sinus tachycardia or a presence of bradycardia via the R-R interval plot.

Long-term electrocardiographic and physiological monitoring over a period lasting up to several years in duration can be provided through a continuously-recording subcutaneous insertable cardiac monitor (ICM). The sensing circuitry and the physical layout of the electrodes are specifically optimized to capture electrical signals from the propagation of low amplitude, relatively low frequency content cardiac action potentials, particularly the P-waves that are generated during atrial activation. In general, the ICM is intended to be implanted centrally and positioned axially and slightly to either the left or right of the sternal midline in the parasternal region of the chest. Additionally, the ICM includes an ECG sensing circuit that measures raw cutaneous electrical signals and performs signal processing prior to outputting the processed signals for sampling and storage.

The invention provides a body-worn patch sensor for simultaneously measuring a blood pressure (BP), pulse oximetry (SpO2), and other vital signs and hemodynamic parameters from a patient. The patch sensor features a sensing portion having a flexible housing that is worn entirely on the patient's chest and encloses a battery, wireless transmitter, and all the sensor's sensing and electronic components. It measures electrocardiogram (ECG), impedance plethysmogram (IPG), photoplethysmogram (PPG), and phonocardiogram (PCG) waveforms, and collectively processes these to determine the vital signs and hemodynamic parameters. The sensor that measures PPG waveforms also includes a heating element to increase perfusion of tissue on the chest.

A system and method for controlling a magnetic resonance imaging (MRI) system to create magnetic resonance (MR) angiograms of a subject. The method includes controlling the MRI system to acquire MR data by performing a pulse sequence that includes at least one set of modules formed by a first /2 module, a (readout, )n module, a second /2 module. In this case, denotes a radiofrequency (RF) flip angle and n denotes a number of times that the set of modules is repeated. The method also includes reconstructing an MR angiogram of the subject from the MR data.

A method includes receiving an input mesh representation of a cardiac chamber, a set of measured locations on a wall tissue of the cardiac chamber, and a respective set of local activation times (LATs) measured at the locations. The input mesh is re-meshed into a regular mesh including regularized polygons. The set of measured locations and respective LATs is data fitted to the regularized polygons. Respective LAT values, and respective probabilities that the wall tissue includes scar tissue, are iteratively calculated for the regularized polygons, so as to obtain an electrophysiological (EP) activation wave over the regular mesh that indicates scar tissue. An electroanatomical map overlaid on the regular mesh, the map including the EP activation wave and the scar tissue, is presented.