Methods and systems for chromatography are disclosed that employ a flexible container configured to fit within a support structure and adapted to receive a filtration or absorptive medium, such as a chromatography resin. The flexible container can include at least one inlet, at least one outlet, and a separation barrier peripherally sealed within the container to separate the container into a resin containing portion and a drainage portion. The barrier can be configured to exclude the resin material from the drainage portion during use while allowing fluids to pass therethrough. The disposable chromatography system can further include one or more agitators disposed within the flexible container and adjustably configured to be raised or lowered in the flexible container. When the agitator is in the raised position, the resin packing material can operate in a settled, packed-bed configuration. Alternatively, the agitator in the lowered position permits the chromatography resin packing material to operate in a mixed, slurry configuration.

According to one embodiment, the liquid crystal material processing device includes a syringe containing contents composed of a liquid crystal material and the like, having a distal end portion constituting a first discharge pipe, an agitation mechanism agitating the contents of the syringe, a vacuum chamber having a second discharge pipe penetrating the bottom to connect to the first discharge pipe of the syringe. The agitation mechanism agitates the liquid crystal material and the pure water in the syringe, and purifies the liquid crystal material by causing water-soluble impurities to transfer to the pure water. The agitation mechanism agitates the liquid crystal material remaining in the syringe after the water layer has been discharged. The evacuation mechanism evacuates the vacuum chamber and causes the liquid crystal material to be degassed while the remaining liquid crystal material is agitated.

A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.

A method for maintaining a fluidic dispensing device includes providing a fluidic dispensing device having a fluid reservoir containing fluid, the fluid reservoir being defined in part by a base wall, and having a stir bar located in the fluid reservoir adjacent to the base wall, and having a fluid ejection chip having a fluid ejection direction; positioning the fluidic dispensing device at a predetermined orientation, wherein the fluid ejection direction is oriented in a range of upward vertical, plus or minus 90 degrees; and rotating the stir bar in a first rotational direction starting with a first rotational speed and increasing rotational velocity from the first rotational speed to a second rotational speed.

A vacuum mixing system for the mixing of polymethylmethacrylate bone cement comprising at least one cartridge (4) having an evacuatable internal space (5) for the mixing of the bone cement, the internal space (5) of which comprises a cylindrical swept volume, a mixing element (12) that is arranged in the internal space (5) of the cartridge (4) such as to be mobile and can be operated from outside the vacuum mixing system in order to mix the content in the internal space (5) of the cartridge (4), and a dispensing plunger (2) having a cylindrical external circumference whose first base surface borders a base surface of the internal space (5) of the cartridge (4) and which can be or is locked to the cartridge (4) in detachable manner and which, in the detached state, is mobile in the cylindrical region of the internal space (5) of the cartridge (4).

An extrusion equipment adapted for supercritical foaming and mixing of a raw material includes a mixing unit, an injection unit for injection of supercritical fluid into the mixing unit, and an extrusion unit for extrusion of the raw material. The mixing unit includes a tube for input of the raw material, and a propelling screw rod and an auxiliary screw rod that are disposed side by side in the tube and that cooperatively compress and propel the raw material. The auxiliary screw rod rotates at a speed at least twice that of the propelling screw rod and in a direction opposite to that of the propelling screw rod.

A bone material comprising a coherent mass of cartridge milled and demineralized bone fibers is provided, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material comprising a lyophilized coherent mass of cartridge milled and demineralized bone fibers is provided, the lyophilized coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a method of making an implantable bone material is provided, the method comprising drying a coherent mass of cartridge milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass.

A vacuum mixing system for the mixing of polymethylmethacrylate bone cement, comprising at least one cartridge (4) having an evacuable internal space for mixing of the bone cement, a pump (18) for generating a negative pressure, and a connecting conduit (12) connecting the internal space of the at least one cartridge (4) to the pump (18) for generating a negative pressure, an integrated energy reservoir (28) for driving the pump (18) that is or can be connected to the pump (18) and has energy for at least one pumping process of the pump (18) stored in it, whereby a negative pressure can be generated by means of the pump (18) during the pumping process, which negative pressure can be used to evacuate gas from the internal space of the at least one cartridge (4) through the connecting conduit (12).

A vacuum blender having the ability to reduce oxidation of ingredients for a more nutrient-rich product. The blender includes a container for holding ingredients to be blended, the container being open at a top end and having blender blades at a lower end, a lid for covering the open end of the container, and a base having a motor contained therein for driving the blender blades, an interface for coupling with the blender blades of the container, a vacuum system for effecting a vacuum to the container and electronic controls for operating the motor and vacuum system. The vacuum system is configured to couple with the lid to draw a vacuum from the top of the container when activated.

Device for the mixing of polymethylmethacrylate bone cement and for storing a monomer liquid and a cement powder as starting components of the bone cement, comprising a cartridge having an internal space closed on one side by a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container which can be opened in the device so that the monomer liquid flows from the monomer container into the device; and a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge; having a pumping plunger that can be shifted axially in the hollow cylinder arranged in the hollow cylinder, which can be used to push monomer liquid from the hollow cylinder through the connecting conduit into the internal space of the cartridge by actuating the pumping plunger.