A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet may be in the form of a mini-tablet which is greater than 70 wt % drug, with the balance being excipient. For example, the anesethetic agent may include lidocaine, in a salt or base form, combined with binder and lubricant excipients. Implantable drug delivery devices including the tablets are also provided, e.g., one or more of the drug tablets may be contained in a biocompatible housing. The drug tablets may be substantially cylindrical with flat end faces, and the device may have from 10 to 100 drug tablets aligned in the housing with the flat end faces of adjacent tablets abutting one another.

A drug dosage form is provided in the form of a solid tablet which is greater than 50% by weight the local anesthetic agent. The local anesthetic agent may be selected from the group consisting of an aminoamide, an aminoester, and a combination thereof. The drug tablet may be in the form of a mini-tablet which is greater than 70 wt % drug, with the balance being excipient. For example, the anesethetic agent may include lidocaine, in a salt or base form, combined with binder and lubricant excipients. Implantable drug delivery devices including the tablets are also provided, e.g., one or more of the drug tablets may be contained in a biocompatible housing. The drug tablets may be substantially cylindrical with flat end faces, and the device may have from 10 to 100 drug tablets aligned in the housing with the flat end faces of adjacent tablets abutting one another.

Systems and methods for treating and packaging cannabis and cannabis-like materials, including systems and methods for sanitizing raw cannabis, and systems and methods for packaging cannabis products in receptacles for sale to and/or use by end users of the products. The systems include treatment systems for treating cannabis by utilizing a rotating conveyor and exposing cannabis on the conveyor to ultraviolet radiation. The systems further include packaging systems for filling receptacles with cannabis utilizing a feed funnel that has a tapering interior that slopes toward a funnel exit port, and an auger or a feed tool at the funnel exit port and extending into the receptacle to deliver a desired dose of the cannabis from the feed funnel.

An apparatus to fill and package capsules in bottles is provided with a dosing line having a dosing unit to feed at least one pharmaceutical or nutraceutical product into the capsules, a pocket conveyor to move the capsules through the dosing unit, and an output station to release the capsules containing the pharmaceutical or nutraceutical product from the pocket conveyor, and a packaging line having a conveyor device to move, in succession, the bottles through a packaging station connected to the output station so as to receive each capsule released by the pocket conveyor and feed it into a respective bottle.

An apparatus to fill and package capsules in bottles is provided with a dosing line having a dosing unit to feed at least one pharmaceutical or nutraceutical product into the capsules, a pocket conveyor to move the capsules through the dosing unit, and an output station to release the capsules containing the pharmaceutical or nutraceutical product from the pocket conveyor, and a packaging line having a conveyor device to move, in succession, the bottles through a packaging station connected to the output station so as to receive each capsule released by the pocket conveyor and feed it into a respective bottle.

An apparatus includes a product metering device, first and second container preparation systems, and a controller. The product metering device is configured to dispense a product. The first and second container preparation systems are configured to dispense first and second containers, respectively, for receiving the product from the product metering device. The first and second container preparation systems include first and second severed container material transporting devices, respectively, operable to transport the first and second containers, respectively, from the first and second container preparation systems, respectively, to the product metering device. The controller simultaneously controls (i) one of the first container preparation system and the second container preparation system to prepare one of the first container and the second container, and (ii) the product metering device to dispense the product into the other of the first container and the second container.

An apparatus includes a product metering device, first and second container preparation systems, and a controller. The product metering device is configured to dispense a product. The first and second container preparation systems are configured to dispense first and second containers, respectively, for receiving the product from the product metering device. The first and second container preparation systems include first and second severed container material transporting devices, respectively, operable to transport the first and second containers, respectively, from the first and second container preparation systems, respectively, to the product metering device. The controller simultaneously controls (i) one of the first container preparation system and the second container preparation system to prepare one of the first container and the second container, and (ii) the product metering device to dispense the product into the other of the first container and the second container.

In an example embodiment, an apparatus for making pouch products includes a conveyor system. The conveyor system includes a first receiving location along a path of the conveyor system, and a dosing location along the path of the conveyor system. The apparatus also includes a first material dispensing station configured to transfer a first material to the first receiving location. The first material includes a first elastic layer and a first support layer. The first material dispensing station includes a dispenser roller configured to hold a roll of the first material, a plurality of rollers configured to convey the first material from the dispenser roller to the first receiving location, and a stripper plate configured remove at least a portion of the first support layer from a portion of the first elastic layer.

A powder sterilization method for sterilizing powder, in particular an active pharmaceutical ingredient in powder form or food in powder form, using fluid vapor, in particular steam. According to the invention, the fluid vapor is applied to the powder in an evacuated treatment chamber (3), in particular it is applied to the powder during its free fall along a drop section (7), in particular in countercurrent.

A powder sterilization method for sterilizing powder, in particular an active pharmaceutical ingredient in powder form or food in powder form, using fluid vapor, in particular steam. According to the invention, the fluid vapor is applied to the powder in an evacuated treatment chamber (3), in particular it is applied to the powder during its free fall along a drop section (7), in particular in countercurrent.