The invention relates to a device comprising a first fixing element, a further fixing element and a folded planar composite; wherein the first fixing element comprises a first fixing surface and the further fixing element comprises a further fixing surface; wherein the folded planar composite is at least partially fixed between the first fixing surface and the further fixing surface; wherein the folded planar composite comprises a first composite region; wherein the first composite region comprises a first layer sequence comprising a first composite layer comprising a first carrier layer, a second composite layer comprising a second carrier layer, a third composite layer comprising a third carrier layer and a fourth composite layer comprising a fourth carrier layer; wherein in the first composite region the second composite layer is joined to the third composite layer and the third composite layer is joined to the fourth composite layer; wherein in the first composite region the third carrier layer is characterised by a smaller layer thickness than in each case one selected from the group consisting of the first carrier layer, the second carrier layer and the fourth carrier layer or a combination of at least two of these; wherein the first fixing surface or the further fixing surface or both comprises a recess comprising a first recess region; wherein the first composite region is located at least partially between the first recess region and the first fixing surface or the further fixing surface.

Disclosed are methods and apparatuses for manufacturing a solid formulation for oral administration, comprising an edible substrate portion on which a composition comprising a first pharmaceutical active ingredient is deposited, and solid formulations made thereby. The methods comprise providing an edible substrate in the form of a film comprising a plurality of portions, spraying a liquid formulation comprising the active ingredient and a solvent onto an edible substrate portion and evaporating the solvent to form a solid composition deposited on the edible substrate portion; measuring the quantity of active ingredient supported by the edible substrate portion and comparing to a predetermined value, and dividing the edible substrate into the plurality of portions.

A fill packaging machine includes a vertical sealing means for folding a packaging film at its central part and continuously forming a vertical sealed portion at its side edge part to shape into a cylinder, and a lateral sealing means for forming lateral sealed portions in a direction perpendicular to the longitudinal direction of the packaging film. An easy separable sealed portion is continuously formed in the side edge part of the packaging film by the first vertical sealed portion forming section, and a vertical sealed portion having a partial non-sealed portion of a bottle mouth type is formed on the easy separable sealed portion by the second vertical sealed portion forming section. The first vertical sealed portion forming section is a pair of heat sealing rolls or heat sealing plates, a surface of at least one of which is made from an elastic material softer than a metal.

A fill packaging machine includes a vertical sealing means for folding a packaging film at its central part and continuously forming a vertical sealed portion at its side edge part to shape into a cylinder, and a lateral sealing means for forming lateral sealed portions in a direction perpendicular to the longitudinal direction of the packaging film. An easy separable sealed portion is continuously formed in the side edge part of the packaging film by the first vertical sealed portion forming section, and a vertical sealed portion having a partial non-sealed portion of a bottle mouth type is formed on the easy separable sealed portion by the second vertical sealed portion forming section. The first vertical sealed portion forming section is a pair of heat sealing rolls or heat sealing plates, a surface of at least one of which is made from an elastic material softer than a metal.

There is described a packaging apparatus (1) for forming a plurality of sealed packages (2) from a tube (3) of a web of packaging material (4) which is continuously filled with a pourable product. The packaging apparatus comprises an isolation chamber (10) separating an inner environment (11) containing a sterile gas from an outer environment (12). The packaging apparatus further comprises a delimiting element (48) arranged, in use, within the tube (3) and being designed to divide the tube (3), in use, into a first space (49) and a second space (50). The packaging apparatus (1) also comprises a pressurizing device (47) for pressurizing the second space (50) by means of a pressurized sterile gas. The delimiting element (48) is arranged within the isolation chamber (10).

There is described a packaging apparatus (1) for forming a plurality of sealed packages (2) from a tube (3) of a web of packaging material (4) which is continuously filled with a pourable product. The packaging apparatus comprises an isolation chamber (10) separating an inner environment (11) containing a sterile gas from an outer environment (12). The packaging apparatus further comprises a delimiting element (48) arranged, in use, within the tube (3) and being designed to divide the tube (3), in use, into a first space (49) and a second space (50). The packaging apparatus (1) also comprises a pressurizing device (47) for pressurizing the second space (50) by means of a pressurized sterile gas. The delimiting element (48) is arranged within the isolation chamber (10).

A protective packaging formation device is provided herein. The device includes an inflation assembly having a fluid conduit that directs fluid between overlapping plies of a polymeric web. The device also includes a driving mechanism that drives the film in a downstream direction. The device also includes a sealing mechanism that includes a thin film heater that heats the plies to create a longitudinal seal that seals the plies of film together. The driving mechanism drives the web such that the web slides across the heating assembly in a downstream direction to trap fluid between the plies.

One embodiment of the present invention includes an apparatus for securing a wrapping material around an item, such as a baled agricultural item, the apparatus including a main plate and at least one projection, the projection including a heating element and a height adjustment mechanism, wherein the height adjustment mechanism controls a force applied to the wrapping material by the projection and provides a force for moving the projection.

A packaging has juxtaposed front and rear panels having juxtaposed upper and lower end edges and juxtaposed side edges extending between ends of the end edges. The side edges are fastened together to define an interior space between the panels. A plurality of longitudinally extending weakened tear lines are formed in and extend along a full longitudinal length of each of the panels. Respective upper and lower transversely extending welds extend along and secure together the upper and lower edges of the panels to longitudinally close the interior space.

A packaging has juxtaposed front and rear panels having juxtaposed upper and lower end edges and juxtaposed side edges extending between ends of the end edges. The side edges are fastened together to define an interior space between the panels. A plurality of longitudinally extending weakened tear lines are formed in and extend along a full longitudinal length of each of the panels. Respective upper and lower transversely extending welds extend along and secure together the upper and lower edges of the panels to longitudinally close the interior space.