Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.

A device and method for automatically stacking packages on a roll container in a predetermined spatial arrangement for forming a stack, comprising at least one feed conveyor which arranges the individual packages in a predetermined order; a lifting and lowering unit for lifting and lowering of the roll container in the Y-direction; at least one sliding plate and one pusher in order to transport the packages in the Z-direction to the predetermined position in the stack; moveable journals being provided in order to separate the lateral walls of the roll container. In a particular embodiment the journals are arranged on rotating disks.

A device and method for automatically stacking packages on a roll container in a predetermined spatial arrangement for forming a stack, comprising at least one feed conveyor which arranges the individual packages in a predetermined order; a lifting and lowering unit for lifting and lowering of the roll container in the Y-direction; at least one sliding plate and one pusher in order to transport the packages in the Z-direction to the predetermined position in the stack; moveable journals being provided in order to separate the lateral walls of the roll container. In a particular embodiment the journals are arranged on rotating disks.

The invention starts from a conveying device (10c) having at least one transport unit (20′c, 20″c) for transporting packaging blanks (12c) and/or containers (14′c, 14″c) in a transport direction (16c) along a transport path (18c), wherein the transport unit has at least one conveying element (24′c, 24″c) which can be driven along a section (22c) of the transport path (18c). It is proposed that at least one conveying element (24′c, 24″c) has a rear side (26′c, 26″c) which in at least one operating state is intended to pull packaging blanks (12c) and/or containers (14′c, 14″c) in the transport direction (16c), and a front side (28′c, 28″c) which in at least one operating state is intended to push packaging blanks (12c) and/or containers (14′c, 14″c) in the transport direction (16c). The invention also relates to a packing machine comprising such a conveying device.

A device for sorting objects includes an input conveyor device with a plurality of input storage devices, which are movable in an input conveying direction. A loading station loads each input storage device with one object. An output conveyor device has a plurality of output storage devices, which are movable in an output conveying direction. A sorting end point discharges the objects. A first transfer region, in which the input conveyor device and the output conveyor device are arranged, allows objects to be transferred from the input storage devices into the output storage devices. A second transfer region, separate from the first transfer region, in which the output conveyor device and the sorting end point are arranged transfers objects from the output storage devices to the sorting end point. An additional sorting end point in the second transfer region enables more flexibly operation of the sorting device.

A device for sorting objects includes an input conveyor device with a plurality of input storage devices, which are movable in an input conveying direction. A loading station loads each input storage device with one object. An output conveyor device has a plurality of output storage devices, which are movable in an output conveying direction. A sorting end point discharges the objects. A first transfer region, in which the input conveyor device and the output conveyor device are arranged, allows objects to be transferred from the input storage devices into the output storage devices. A second transfer region, separate from the first transfer region, in which the output conveyor device and the sorting end point are arranged transfers objects from the output storage devices to the sorting end point. An additional sorting end point in the second transfer region enables more flexibly operation of the sorting device.

A caster wheel alignment system for selectively re-orienting improperly oriented caster wheels for transport vehicles of a conveyor system, such as a circular sorter. The alignment system includes a main support frame couplable with the conveyor at a drive track of the conveyor. The system includes a horizontal cam for adjusting an orientation of the caster wheel from a leading orientation to a trailing orientation. In some forms, the alignment system may include a bypass system, such as a float frame, supporting the horizontal cam, and a vertical cam. The vertical cam provided to temporarily move the float frame and horizontal cam away from the transport vehicle and/or drive track to permit the vehicle to move through the alignment system. The vertical and horizontal cams coordinate to intercept and correct improperly oriented wheels without significantly impeding the movement of the transport vehicle along the drive track.

An illustrative example tube handling machine includes a lifter configured to receive a plurality of tubes when at least a portion of the lifter is at a first position. The lifter is configured to lift the plurality of tubes to a second, higher vertical position. A plurality of cells are respectively configured for at least temporarily holding the plurality of tubes. A first one of the cells is situated to receive the plurality of tubes from the lifter at the second vertical position. The cells are situated relative to each other such that the plurality of tubes can be sequentially transferred among the cells from the first one of the cells to a last one of the cells that releases the plurality of tubes to a delivery location.

An illustrative example tube handling machine includes a lifter configured to receive a plurality of tubes when at least a portion of the lifter is at a first position. The lifter is configured to lift the plurality of tubes to a second, higher vertical position. A plurality of cells are respectively configured for at least temporarily holding the plurality of tubes. A first one of the cells is situated to receive the plurality of tubes from the lifter at the second vertical position. The cells are situated relative to each other such that the plurality of tubes can be sequentially transferred among the cells from the first one of the cells to a last one of the cells that releases the plurality of tubes to a delivery location.

A modular transfer system with a primary flow system and a diverter system. The primary flow system includes a primary flow belt for conveying an article along a primary flow path from an infeed side of the modular transfer system to a pass-through side of the modular transfer system. The diverter system includes one or more diverter belts for diverting an article from the primary flow path towards a divert side of the modular transfer system. The primary flow belt includes multiple movable components contacting the diverter belt. The movable components can have one or more rotational degrees of freedom.