Techniques regarding a vertical nanofluidic channel array are provided. For example, one or more embodiments described herein can regard an apparatus that can comprise a semiconductor substrate and a dielectric layer adjacent to the semiconductor substrate. The dielectric layer can comprise a first nanofluidic channel and a second nanofluidic channel. The second nanofluidic channel can be located between the first nanofluidic channel and the semiconductor substrate.

A microfluidic device (100) for mixing a liquid L is provided. The microfluidic device (100) comprises a microfluidic chamber (20), having an inlet (30), and arranged to receive the liquid L therein. In use, the microfluidic device (100) is arranged to control translation through the liquid L of a body B introduced therein, wherein the translation of the body B is due to a potential field acting on the body. In this way, the controlled translation of the body B mixes the liquid L in the microfluidic chamber (20).

The invention is directed to a microfluidic device, which comprises distinct, parallel levels, including a first level and a second level. It further includes: a first microchannel, a second microchannel, and a node. This node comprises: an inlet port, a cavity, a via, and an outlet port. The cavity is formed on the first level and is open on a top side. The inlet port is defined on the first level; it branches from the first microchannel and communicates with the cavity through an ingress thereof. The outlet port, branches to the second microchannel on the second level. The via extends from the bottom side of the cavity, down to the outlet port, so the cavity may communicate with the outlet port. In addition, the cavity comprises a liquid blocking element to prevent an aqueous liquid filling the inlet port to reach the outlet port.

A method for producing a cavity in a substrate composed of hard brittle material is provided. A laser beam of an ultrashort pulse laser is directed a side surface of the substrate and is concentrated by a focusing optical unit to form an elongated focus in the substrate. Incident energy of the laser beam produces a filament-shaped flaw in a volume of the substrate. The filament-shaped flaw extends into the volume to a predetermined depth and does not pass through the substrate. To produce the filament-shaped flaw, the ultrashort pulse laser radiates in a pulse or a pulse packet having at least two successive laser pulses. After at least two filament-shaped flaws are introduced, the substrate is exposed to an etching medium which removes material of the substrate and widens the at least two filament-shaped flaws to form filaments. At least two filaments are connected to form a cavity.

A liquid handling device has an accommodation part for accommodating a liquid, two or more flow paths each opening to a lower part of a side wall surface of the accommodation part, and a liquid movement suppression part that is disposed in the lower part of the side wall between the openings of two of the flow paths that are adjacent to each other and slows or stops the movement of the liquid along the corner formed by the lower surface of the accommodation part and the side wall surface.

Techniques regarding a vertical nanofluidic channel array are provided. For example, one or more embodiments described herein can regard an apparatus that can comprise a semiconductor substrate and a dielectric layer adjacent to the semiconductor substrate. The dielectric layer can comprise a first nanofluidic channel and a second nanofluidic channel. The second nanofluidic channel can be located between the first nanofluidic channel and the semiconductor substrate.

A microfluidic device (100) comprising: a substrate (110) having a liquid channel (120), an ordered set of pillars (130) positioned in the channel (120), the individual pillars (130) comprising at least one pair of fins that form a chevron-shaped cross-section with the substrate, and being arranged in pairs of rows, adjacent rows being laterally displaced with respect to one another by half a pillar in length, the pillar length being measured perpendicular to the average liquid direction, thereby forming microchannels between the pillars, and the rows being staggered so that the microchannels formed between pillars of successive rows at each position along the longest pillar side have substantially the same width.

A photothermal nanostructure device for photothermal heating includes a substrate having a first thermal conductivity, a light absorbing layer on a first side of the substrate and configured to absorb light in a wavelength range and to heat the substrate, and a thermally-insulative layer on the light absorbing layer and configured to reduce heat dissipation from the substrate, the thermally-insulative layer having a second thermal conductivity less than the first thermal conductivity.

The describes example systems, devices, and techniques. In one example, a device includes a body extending away from a substrate, which includes a first end with an open-facing port configured to allow introduction of a tissue sample, and a second end that forms an open outlet proximal the major surface of the substrate. At least a portion of the body includes therein a tissue chamber for the tissue sample. At least one microfluidic channel on the major surface of the substrate is fluidly connected to the tissue chamber, and includes an inlet upstream of the tissue chamber and an outlet downstream of the tissue chamber. A separation element is between the tissue chamber and the at least one microfluidic channel. The tissue chamber, the separation element and the microfluidic channel occupy a single layer on the substrate.

A template based process is used for the production of the nanowire structural element, wherein the nanowires are electrochemically depositioned in the nanopores. The irradiation is carried out at different angles, such that a nanowire network is formed. The hollow chamber-like structure in the nanowire network is established through the dissolving of the template foil and removal of the dissolved template material. The interconnecting of the nanowires provides stability to the nanowire structural element and an electrical connection between the nanowires is created thereby.