Devices for the separation of components within a fluid are disclosed herein. The device typically includes layers of spacers and separation surfaces. The separation panels have channels with functionalized surfaces to attract and retain components within the fluid. The separation panels include a border (housing) to constrain the fluid.

A method reduces variation of measured data when nucleic acid is separated from a very small amount of sample followed by detection of the nucleic acid, wherein the reduction of the variation is achieved by removing contaminant nucleic acid in a nucleic acid purification column. The method of separating the nucleic acid from the sample containing the nucleic acid includes bringing the sample containing the target nucleic acid into contact with a nucleic acid-binding solid-phase carrier capable of adsorbing the nucleic acid; and eluting the nucleic acid from the nucleic acid-binding solid-phase carrier to which the nucleic acid is adsorbed.

A method reduces variation of measured data when nucleic acid is separated from a very small amount of sample followed by detection of the nucleic acid, wherein the reduction of the variation is achieved by removing contaminant nucleic acid in a nucleic acid purification column. The method of separating the nucleic acid from the sample containing the nucleic acid includes bringing the sample containing the target nucleic acid into contact with a nucleic acid-binding solid-phase carrier capable of adsorbing the nucleic acid; and eluting the nucleic acid from the nucleic acid-binding solid-phase carrier to which the nucleic acid is adsorbed.

The present technology relates to a novel sanitization method for chromatography media and supporting equipment comprising treatment with a sanitization/sterilization solution comprising acetic acid and hexylene glycol.

There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.

A method and system for solid phase extraction of a compound of interest from a sample matrix using a syringe having a barrel and a plunger, a sorbent for use with the syringe, and a desalting purification column having an end configured to receive liquid from the syringe body.

A method and system for solid phase extraction of a compound of interest from a sample matrix using a syringe having a barrel and a plunger, a sorbent for use with the syringe, and a desalting purification column having an end configured to receive liquid from the syringe body.

A polymer for liquid chromatography or solid phase extraction is provided. The polymer is prepared by polymerizing styrene and divinylbenzene to form a styrene-divinylbenzene copolymer; soaking the styrene-divinylbenzene copolymer in a swelling agent to form nano-scale micropores; and soaking the microporous styrene-divinylbenzene copolymer in methanol. When packed in a chromatographic column, the polymer can be used to produce produce natural health or medicinal products from Cannabis species, for example, industrial hemp.

The disclosure provides systems and methods useful for predicting or detecting a malfunction in a chromatography process in real-time. In some embodiments, the disclosure provides systems and methods for detecting an atypical profile in a process chromatogram in ion-exchange chromatography of a biologic product.

Distribution and collection panel comprising an upper screen (4), a collector (5), a separation plate (6) with outlet openings (11), a distributor (7), a lower screen (8), an injection/withdrawal tank (9) adjacent to the separation plate, and a jet breaker element (12) perpendicular to the flow (E) of a main fluid and comprising two solid jet breaker plates (13) that are: extended on either side of the injection/withdrawal tank; juxtaposed with the lower screen; disposed beneath the outlet openings (11); designed to direct the main fluid in the distributor in a direction orthogonal to the direction of the flow (E), the ratio I/L of the width I of the solid jet breaker plate to the width L of the lateral part of the separation plate being at least 0.1.