A high volume microfluidic system for producing emulsions includes a fluid distribution network to produce uniformly sized emulsions and encapsulates.

What is proposed is an emulsifying system with an emulsifying device and an injection nozzle as well as an emulsifying device for producing a water-fuel emulsion for an internal combustion engine, wherein the emulsifying device is embodied as a rotor-stator emulsifying device and/or fluid flow machine and/or is connected or connectable directly to an injection nozzle. The emulsifying device has a housing and a shaft, the shaft being drivable in a contactless manner, the housing having a guide apparatus having a plurality of guide channels for guiding the flow, and/or the housing being made at least partially from fiber composite material. Moreover, an emulsifying method for producing a water-fuel emulsion is proposed in which water and fuel are fed to a rotor-stator emulsifying device and/or fluid flow machine for producing the water-fuel emulsion, and/or in which water and fuel are premixed in a first emulsifying stage and fed via a guide apparatus having a plurality of guide channels to a second emulsifying stage.

The present invention discloses an improved nanoemulsion comprising a uniform and discrete range of very small particle nano-sized diameters. This uniformity results in improved bioavailability of incorporated compounds (i.e., pharmaceuticals or nutraceuticals) as reflected in various pharmacokinetic parameters including, but not limited to, decreased Tmax, increased CmaX3 and increased AUC. The improved method of making these uniform nanoemulsions utilizes microfluidization which differs in both process and mechanics when compared to conventional milling and grinding techniques used to generate nanoparticulate compositions. Further, the improvement results, in part, from a novel step of mixing a substantially soluble compound into a heated dispersion medium. This is unlike current nanoparticulate composition methods that mix an insoluble compound with an unheated dispersion medium. Further, these nanoemulsions are observed to be bacterial-resistant and stable to extremes in both temperature and pH changes. Consequently, these nanoemulsions are expected to have a significantly prolonged shelf-life than currently available nanoemulsions.

A method for producing a composition having a disperse phase with small particle size dispersed in a continuous phase and having greater than 20% by volume of a disperse phase. The method comprising a permeation step, wherein a mixture of a continuous phase liquid and a disperse phase liquid simultaneously permeate a circumferential surface of a cylinder, which is partially or wholly composed of a porous membrane. The cylinder having outlets for the composition in the cross sections of both ends of the cylinder. The porous membrane having an average pore size of not smaller than 5 m at a membrane permeation rate of not lower than 50 m.sup.3/m.sup.2h. The porous membrane cylinder having a longitudinal effective membrane length, L, the internal diameter of the outlets, d, and the membrane permeation rate, F, which satisfy the relationships disclosed herein of L/d and F.

Disclosed herein are instruments and methods for performing both sample homogenization and sample clarification by centrifugation with a single instrument without transferring the sample to a new sample container and without removing or repositioning the sample container within the instrument. In some embodiments, the instrument may automatically perform centrifugation after homogenization. In other embodiments, the instrument may perform both homogenization and centrifugation simultaneously.

A liquid dispersion device according to the present invention includes at least one liquid flow member attachable to a rotary shaft. The liquid flow member includes at least one tubular suction portion extending along the rotary shaft and including a suction port at a lower end thereof and at least one ejection portion extending in a direction inclined with respect to the suction portion and having one end that is in communication with an upper end of the suction portion and another end that includes an ejection port.

A method for optimizing a Hegman rating of a diluted emulsion including adjusting the shear work in the dilution mixer, wherein the adjusting the shear work may comprise raising or lowering the shear work; adjusting the temperature of the concentrated and/or diluted emulsion; if not earlier added, adding a basic aqueous solution and/or dispersing agent; adding one or more other additives; and/or adjusting the amount of any additive, basic solution or surfactant solution is provided. Also provided are diluted emulsions produced thereby and coatings made from the diluted emulsions.

A method for encapsulating active ingredients in liposomes having an active ingredient solution encapsulated with a bilayer composed of two monomolecular layers of amphiphilic compounds comprises: (a) providing the active ingredient solution; (b) providing an emulsion by emulsifying the active ingredient solution in a first liquid in the presence of the amphiphilic compound; (c) providing a liquid phase; (d) contacting the emulsion with the liquid phase to form a phase boundary; and (e) centrifuging the emulsion and the liquid phase that are in contact with one another via the phase boundary, wherein, on passage of the phase boundary, the amphiphilic compound enriched there is added onto the monomolecular inner layer to form a monomolecular outer layer, in order to create the bilayer. The first liquid of the emulsion is chosen such that the solubility of the amphiphilic compound in the first liquid is not more than 110.sup.4 mol/l.

The invention relates to a method for adding hops in beer manufacture, having the following process steps; a) separation of a sub-quantity (07a) of water and/or wort (07) and/or beer as an aqueous fluid, b) addition of hop extract (10) in liquid or pasty form to the separated aqueous fluid (07a), c) production of a macroemulsion (13) of the hop extract by emulsifying the hop extract (10) in the aqueous fluid (07a), d) increasing the pressure in the macroemulsion (13) of the hop extract to a feed pressure of in particular higher than 100 bar, e) production of a microemulsion (17) of the hop extract by feeding the pressurized macroemulsion (13) through a gap or a valve (16) or by feeding the pressurized macroemulsion against a baffle plate, f) at least partial return of the microemulsion (17) of the hop extract to the beer manufacturing process.

Provided is a homogenizer with a back flushing structure. A homogenizer for homogenizing a raw material comprises a first guiding block 13a for guiding the raw material to flow with an operation of a plunger 12; a first flow controlling valve 14a connected to the first guiding block 14a; an inflow regulating unit 15a connected to the first flow controlling valve 14a; at least one nano cell block for homogenizing the raw material being inputted through the inflow regulating unit 15a; a discharge regulating unit 15b for regulating a discharging of the homogenized raw material discharged from the nano cell block 16a, 16b; a second guiding block 13b installed between the plunger 12 and the first guiding block 13a; a second flow controlling valve 14b for connecting the second guiding block 13b to the discharge regulating unit 15b; and a heat exchanger 18 connected to the discharge regulating unit.