The subject matter described herein includes apparatus's and methods for storing and mixing materials such as powders and liquids. The mixing apparatus can comprise an impeller portion configured to rotate downward or upward within the main cup, wherein a movement of the impeller portion downward or upward is capable of mixing the contained set of substances, wherein the impeller portion comprises a set of propeller blades, and wherein the impeller portion is connected to a helical shaft portion comprising a first helical strand and a second helical strand wound uniformly in a parallel spiral configuration. The impeller portion facilitates a distributed mixing of the substances and the propeller blades are capable of removing deposits of the substance around the base of a main cup of the apparatus.

One aspect relates to a device to produce a bone cement paste from a monomer liquid and a cement powder as starting components of the bone cement paste, and to dispense the mixed bone cement paste. The device includes a cartridge with a cylindrical interior, a dispensing plunger movable towards the front of the cartridge; a receptacle extending along a longitudinal direction, a front of the receptacle connected with the rear of the cartridge; a pumping plunger arranged and in the receptacle movable towards the front of the receptacle; a breakable ampoule containing the monomer liquid, the ampoule with ampoule body arranged in the receptacle between the pumping plunger and the dispensing plunger with at least some sections of the ampoule body in contact with the receptacle; and a spacer arranged in the receptacle between the dispensing plunger and the ampoule body, the spacer extending in the longitudinal direction of the receptacle and the spacer being separated from the inner wall of the receptacle by a distance at least as large as the wall thickness of the ampoule body.

A device for mixing bone cement comprises a first hollow body which encloses a first cavity for receiving a powder and has a first opening, and a second hollow body which encloses a second cavity for receiving an ampoule and has a second opening. The first hollow body and the second hollow body are connectable to one another in such a way that the first opening and the second opening are fluidically connected to one another. The first hollow body is elastic so that a content of the first hollow body can be mixed from the outside by kneading.

The invention relates to a device and method for producing a bone cement paste (54) from a monomer liquid (4) and a cement powder (5). The device includes a cartridge (1) with a cylindrical interior chamber for mixing the parent components, whereby the interior chamber of the cartridge (1) is closed on the front side up to a delivery opening for expelling the bone cement paste (54) from the interior chamber, a delivery plunger (7) which is arranged in the interior chamber of the cartridge (1) and which is supported in a linearly movable manner in the direction of the delivery opening, the cement powder (5), which is arranged in the interior chamber of the cartridge (1) between the delivery opening and the delivery plunger (7), a monomer receptacle (2) with an interior chamber in which a monomer liquid container (3) containing the monomer liquid (4) is contained, whereby in the monomer receptacle (2), a conveying plunger (6) is arranged movable in the longitudinal direction of the monomer receptacle (2), a compressed gas connection (8), which is directly connected or connected via a compressed gas line in a pressure-tight manner with the interior chamber of the monomer receptacle (2), whereby the conveying plunger (6) is arranged between the monomer liquid container (3) and the compressed gas connection (8) or the compressed gas line in the monomer receptacle (2), and a connection (14) which connects the interior chamber of the monomer receptacle (2) and the interior chamber of the cartridge (1) which is permeable for the monomer liquid (4) but impermeable for the cement powder (5), whereby the monomer liquid container (3) is arranged between the conveying plunger (6) and the connection (14).

A reagent delivery method includes placing a reagent delivery column including a plurality of reagent storage elements therein in a centrifugal device, coupling a breaching element to the housing, and rotating the centrifugal device to force the reagent storage elements toward the breaching element, breaching of the reagent storage elements releasing reagent therein and communicating the same to an external environment. A reagent delivery system includes a column having a housing, a plurality of reagent storage element sheets positioned in the housing or forming a stack, a plurality of breaching elements, and a microplate having a plurality of wells, the microplate coupled to the housing where each well corresponds or aligns with a breaching element and a reagent storage element. The system can be rotated in a centrifugal device to force the reagent storage element stacks toward the breaching elements.

Systems for a plastic pump/actuator capable of containing and pumping organic solvents and lubricants and having a more desirable lubricity within the system. The system has at least two cylinders, with plungers therein, oppositely disposed from each other and configured to operably connect to a pump.

The subject matter described herein includes apparatus's and methods for storing and mixing materials such as powders and liquids. The mixing apparatus can comprise an impeller portion configured to rotate downward or upward within the main cup, wherein a movement of the impeller portion downward or upward is capable of mixing the contained set of substances, wherein the impeller portion comprises a set of propeller blades, and wherein the impeller portion is connected to a helical shaft portion comprising a first helical strand and a second helical strand wound uniformly in a parallel spiral configuration. The impeller portion facilitates a distributed mixing of the substances and the propeller blades are capable of removing deposits of the substance around the base of a main cup of the apparatus.

One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder as parent components of the bone cement paste and for delivering the mixed bone cement paste, the device having a cartridge having a cylindrical interior. The interior of the cartridge is closed on the front side except for a delivery opening for expelling the bone cement paste. A delivery plunger is arranged in the interior of the cartridge. The cement powder is arranged in the interior of the cartridge. A closure is arranged on the front side of the delivery plunger. The closure closes the delivery opening when the delivery plunger is pressed against the front side of the interior of the cartridge. The closure blocks a further movement of the delivery plunger so that the delivery plunger is spaced from the front side of the interior of the cartridge at least in some areas and a dead volume remains in the interior of the cartridge when the delivery plunger is pressed against the front side of the interior of the cartridge.

The subject matter described herein includes apparatus's and methods for storing and mixing materials such as powders and liquids. The mixing apparatus can comprise an impeller portion configured to rotate downward or upward within the main cup, wherein a movement of the impeller portion downward or upward is capable of mixing the contained set of substances, wherein the impeller portion comprises a set of propeller blades, and wherein the impeller portion is connected to a helical shaft portion comprising a first helical strand and a second helical strand wound uniformly in a parallel spiral configuration. The impeller portion facilitates a distributed mixing of the substances and the propeller blades are capable of removing deposits of the substance around the base of a main cup of the apparatus.

A closed-type medicine mixing extraction device for mixing and extracting medicines stored in a first vial and a second vial, respectively, includes a first needle part and a second needle part, which are able to be fitted to the first vial and the second vial, respectively, a connection port to which a syringe is able to be coupled, and a ventilation port through which air is able to enter and exit, wherein the first needle part and the second needle part communicate with each other through a direct communication flow path, the first needle part and the connection port communicate with each other through an extraction flow path, and the second needle part and the ventilation port communicate with each other through a ventilation flow path. Thus, different types of medicines stored in vials, respectively, are able to be hygienically, safely, and rapidly mixed and extracted.