Pipette assembly comprising a pipette device, a pipette tip, and an expanding mandrel collet coupling device coupling the tip to the pipette device, the coupling device comprising: circumferentially spaced apart segments, an annular base disposed below the segments and comprising a distal portion, an elastomeric element circumscribing the distal portion, and upwardly extending circumferentially spaced apart arms attached at first ends to the annular base and having upper free ends each supporting a different one of the segments configured to expand between a first and a second greater circumference for engaging a first interior working surface of the tip in concurrence with the elastomeric element sealing against a second interior working surface below the first surface and in concurrence with an abutment between a disk exteriorly disposed about a medial portion of the arms and a stepped interior shoulder of the tip disposed between the first and second working surfaces.

Multivolume liquid pipettes with nested plunger and vacuum chamber configurations and methods of using such pipettes are disclosed herein. These pipettes typically include a body and a fluid displacement assembly with a small plunger element slideably received within a larger plunger element, each movable within a vacuum chamber for the precise and accurate control of the displacement of fluid, such as air. In turn, this allows for a single device to aspirate and dispense a broad range of liquids in a dynamic, accurate, and precise manner. In addition, the devices disclosed herein may also include a multi-tiered spring-loaded ejection mechanism to allow the user to use and eject pipette tips of different sizes.

A positive displacement sampling pipette which includes a control rod, the bottom end of which controls the displacement of a device for gripping the top end of a piston of a capillary-piston assembly intended to cooperate with said pipette. The pipette includes an ejection rod of the capillary-piston assembly, movably mounted with respect to the control rod such that its bottom end exerts an ejection strain on the top end of the piston accommodated in the gripping device during a relative displacement between the ejection rod and the control rod.

The present invention relates to a coupling formation of a pipetting channel of a pipetting device for coupling of an implement, for instance a pipette tip, or a laboratory instrument, laboratory tool or the like, thereto, wherein the coupling formation surrounds a pipetting channel section which extends along a pipetting channel axis which defines an axial direction, wherein the coupling formation additionally has, at its free longitudinal end, a pressure-imparting orifice into which the pipetting channel section opens and has, at its radially outer surface which surrounds the pipetting channel axis and extends principally in axial direction and in peripheral direction about the pipetting channel axis relative to the pipetting channel axis, a coupling projection which yields in the radial direction, which is characterized in that the coupling projection is provided so as to be essentially undeformable but radially movable on a spring arrangement which is elastic in radial direction.

A mechanism that provides an improved method of loading and unloading a row of disposable pipette tips onto a handheld multichannel pipettor. A single button fur tip load and unload operations is simpler than the current method of using a separate mechanism for ejecting the tips. The tips are configured in a rigid collar which is held by a clamp on the pipettor. An upward force combined with a sealing gasket that mates with the top of the pipette tips is used to provide the seal between the tips and the pipettor. This eliminates the requirement to “press downward” with excessive force in order to force the pipette tips onto a protruding sealing part. The loading and unloading of tips will be more reliable and repeatable, this providing better pipetting results. The low forces of the loading and unloading operations reduce the chance of repetitive stress injury for the operator.

A sample injector for injecting a fluid into a fluidic path, wherein the sample injector comprises a robot arm configured for moving an injection needle, when being connected to the robot arm, between a fluid container containing the fluid and a seat in fluid communication with the fluidic path, the needle configured for aspirating the fluid from the fluid container, when the needle has been moved to the fluid container, and for injecting aspirated fluid into the fluidic path, when the needle is accommodated in the seat, and the seat configured for accommodating the needle and providing fluid communication with the fluidic path, wherein the robot arm is configured for selectively disconnecting the needle from the robot arm when the needle is accommodated in the seat, and wherein the robot arm is configured for performing a further task while the needle is disconnected from the robot arm.

A pipette comprises a pipette housing comprising an upper end and a lower end, a nipple configured to contact and retain a pipette tip, a drive apparatus configured to aspirate a liquid specimen into the pipette tip and expel the liquid specimen from the pipette tip, and an ejection apparatus. The ejection apparatus comprises a curved support rotatably mounted within the pipette housing, an ejection rod, a first sensing element positioned on the ejection rod and configured to be guided on a first curve on a perimeter of the curved support, and an operating element coupled to the curved support and configured to rotate relative to the pipette housing. The ejection apparatus is configured to rotate the curved support out of a start position by rotating the operating element. The first curve displaces the first sensing element downward a the ejection rod moves the pipette tip off of the nipple.

A pipette tip made of plastic includes a tubular body having an inner circumference and an outer circumference. The tubular body includes a bottom end defining a bottom opening structured to enable passage of a liquid and a top end defining a top opening that clamps onto a mount of a pipetting device. A seat region for the mount is positioned proximate to the top opening and on the inner circumference of the tubular body. A plurality of flattenings extend in an axial direction on the outer circumference proximate to the top opening. The tubular body defines a contour of an arc polygon in a cross-section through the flattenings on the outer circumference.

A handheld multichannel air displacement pipette is modular in construction and includes compliant joints and molded plastic components in place of various machined metal, glass, and ceramic components found in traditional multichannel pipettes. These improvements are made without sacrificing performance in channel-to-channel consistency, accuracy, and precision. The multichannel pipette is inexpensive to manufacture, lightweight, reliable, and easy to assemble and service.

Provided in part herein are pipette tip rack assemblies having one or more of the following features: (i) having a plurality of pipette tip receptacle plates, each plate having an array of pipette tips, stacked upon one another supported by a rack base; (ii) each plate having one or more projections from the proximal or distal surface and, optionally, orifices that oppose the projections of the next plate in the stack, and (iii) the rack base having a proximal surface with one or more orifices or projections that oppose the projections or orifices of the plate in the stack. Also provided are methods of dispensing pipette tips from pipette tip rack assemblies and manufacturing pipette tip rack assembly components.