A transfer container for a fluid includes a tube, the tube including a conical portion at one end, the tube defining an interior space and one or more fluid passages configured to allow flow of fluid into or out of the interior space of the tube. The transfer container also includes a connector configured to seal the end of the conical portion when the connector is joined only to the conical portion and a pressure control mechanism configured to increase or decrease a pressure in the interior space of the tube. The transfer container can be used in a method including connecting fluid lines to the fluid passages, adding a fluid including cryoprotectant and cells, centrifuging the transfer container, and then connecting the transfer container to a second fluid transfer container containing another fluid. This allows the sterile transfer of fluids and separation of cells from cryoprotectant.

The present disclosure provides a cell harvesting method for the efficient sedimentation and retention of cells from liquid samples onto a solid support with low cell losses and low impact on cell morphology.

A centrifuge unit for a microfluidic device for processing liquid samples includes a centrifuge cup and at least one centripetal force-dependent valve function.

A centrifugal reaction microtube, centrifugal reaction device and its centrifugal examination method are provided to achieve easy, quick operation, safety, energy saving, precision, cost effectiveness, and prevention of contamination by controlling a centrifugal force and using a uni-directional valve in the centrifugal reaction microtube.

A system for preparing a thrombin serum that can include a containment device, a cage received within the containment device, a cap attachable to the containment device, an inlet port configured to introduce a non-anti-coagulated autologous blood fluid into the containment device, and an outlet port. An activator, such as glass beads, can be present within the containment device.

The present invention may include an upper cap having an opening/closing member for opening and closing an inlet through which a blood is injected; a main body housing having an open upper end outer surface thereof assembled with the upper cap, and having an inner space in which the blood is filled with; an adjustment housing that is coupled to the main body housing to seal the open lower end of the main body housing, and is movably assembled with respect to the main body housing so that a buffy coat layer is positioned on a neck portion; and a side cap fixed to the neck portion by forming a needle hole through which an end of an injection needle for extraction enters and exits in area corresponding to a sealing member to seal an extraction hole formed through the neck portion.

A biological false bottom transport tube system includes a top section manufactured from a top section material and a bottom section below an interior floor. The top section material is transparent to both visible and infrared light, the bottom section fits within the bottom of the top section. The bottom section material is not transparent to either visible or infrared light.

The present disclosure pertains to sample preparation devices useful for affinity capture and purification that include one or more internal structures that comprise a reservoir, a well, a fluid passageway, sorbent particles, and a filter element that blocks passage of the affinity sorbent particles, which sample preparation devices combine the attributes of both dispersive and flow through designs into a single sample preparation device. The present disclosure also pertains to kits that contain and methods that use such sample preparation devices.

The present disclosure generally provides centrifuge container adapters configured to be used in a centrifuge, e.g., a bench-top centrifuge, and centrifuge systems and methods incorporating the centrifuge container adapters. The centrifuge container adapter may receive a centrifuge container, comprising a sample, the sample, in turn, comprising a fluid. During a centrifuging operation, according to some embodiments, the centrifuge container adapter and centrifuge container may be placed in a rotor cavity in the centrifuge. As a rotor of the centrifuge spins, the fluid may exit the sample within the centrifuge container and be collected in a void space of the centrifuge container adapter. In some embodiments, measurements of the fluid in the centrifuge container adapter may be used to determine characteristics or properties of the sample.

The present invention relates to improved methods for processing fluids and to a fluid processing device (1) for use in a centrifuge comprising: (a) a first holder (14) form-fit to the shape of a first tube (18) for holding said first tube (18) whereby said first tube (18) has a first cross section (A1); and (b) a second holder (22) form-fit to the shape of a second tube (26) for holding said second tube (26) whereby said second tube (26) has a second cross section (A2) that is different from said first cross section (A1). With the fluid processing devices and the methods according to the invention, it is possible to simplify the centrifugal processing steps for a given fluid processing sequence and to automate them.