Patent classifications
B01L3/5021
METHOD FOR COLLECTING AND PRESERVING A BIOLOGICAL SAMPLE
The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g., saliva, urine), which can then be subjected to processing to extract a plurality of cells. The plurality of cells can be further processed to isolate one and/or another cell type therefrom. The plurality of cells, as well as the isolated cell type(s), can be analyzed for functional genomic and epigenetic studies, as well as biomarker discovery.
Microchannel analyzing device having a filling confirmation region
An analyzing device has a main body and is configured to draw a sample liquid from a spot application section of the main body and transfer the sample liquid to a measurement chamber via a microchannel structure formed inside the main body by a centrifugal force. The spot application section has an inlet. The analyzing device includes a supplying capillary channel formed within the spot application section. The supplying capillary channel has an end connected to the inlet of the spot application section. The analyzing device also includes a holding chamber connected to another end of the supplying capillary channel and having a thickness sized to generate a capillary force to move the sample liquid. The holding chamber is formed between a first side wall and a second side wall. The first side wall and the second side wall define the holding chamber.
Integrated kit for separating blood and concentrating PRP and method for extracting PRP using the same
An integrated kit for separating blood and concentrating PRP includes: (a) a main body that includes an upper storage portion, a lower storage portion, and a passage portion for connecting the upper storage portion and the lower storage portion; (b) a upper cover coupled to an upper end of the upper storage portion; (c) an inner stopper inserted into a lower end of the lower storage portion so as to seal the lower storage portion; (d) a closing adjustment screw which can move vertically while penetrating a hole formed at the inner stopper and seals the passage portion; and (e) a lower cover coupled to an outside of the lower end of the lower storage portion and the outside of the inner stopper to prevent the separation of the closing adjustment screw coupled to the inner stopper in case of centrifugation.
DEVICE AND SYSTEM FOR PRESERVING ANALYTES IN BLOOD SAMPLES DURING STORAGE AND TRANSPORTATION
Freshly obtained blood samples are deposited into a device that contains blood sample carriers, each of the carriers is designed to hold a fixed amount of blood and allow excess blood sample to flow through and be discarded. A desiccant within the blood sample carrier aids with the drying of the blood and the discarding of the excess sample blood. The device is stored/transported within a modified atmosphere package comprised of an impermeable sealable bag and an oxygen scavenger compound for removing oxygen from the bag.
BIOPSY CARRIER
The present invention relates to a device adapted to facilitate transport of a biopsy sample from a sterile extraction site to laboratory-type equipment by which the biopsy sample is processed, while maintaining the biopsy sample wetted and sterile and automatically transferring the biopsy sample from the device to the laboratory-type equipment.
MEDICAL STRING KIT
An apparatus comprising a string for insertion into the oesophagus of a patient, the string comprising proximal end and a distal end, wherein the string forms a structure at the distal end thereof to assist in the insertion of the string into the patient.
Mixing element for container assemblies
A container assembly with improved mixing dynamics for mixing substances in preparation for injection by an injection device or for the dispersion of additives in the collection and analysis of biological samples is disclosed. In one configuration, the container assembly includes a first mixing element protruding into an interior of a container. With the container rotated about its longitudinal axis, the first mixing element forms at least one vortex which effectuates mixing of a first substance provided within the container interior and a second substance provided within the container interior.
CENTRIFUGE TUBE, DETECTION SYSTEM AND DETECTION METHOD
The centrifuge tube includes: a tube body comprising an inner surface and an outer surface, a sensor provided at the inner surface of the tube body and comprising a first electrode group; and a second electrode group provided at the outer surface of the tube body and electrically connected with the first electrode group.
A FLUID COLLECTION DEVICE
This invention relates primarily to a fluid collection device for laboratory analysis. Accordingly, the fluid collection device (100) includes a specimen collection tube assembly (200); characterised in that the specimen collection tube assembly (200) comprises: a) a barrel (210) defining a first chamber (211); b) an inner tube or plunger (220) defining a second chamber (221). It should be noted that the barrel (210) is provided with a luer tip (214) at one end, and another end (215) is in slidable sealing engagement with the inner tube (220) defining a closed system thereof. The inner tube (220) is provided with a luer tip (224) at one end, and the opposite end is equipped with a seal (222) separating the first and second chambers (211 and 221) in said closed system. It should be noted that a conduit (212) is selectively provided either at the luer tip (224) of the inner tube (220) extended towards the second chamber (221) or from the luer tip (214) of the barrel (210) extended towards the first chamber (211). The luer tip (214) of the barrel (210) and the luer tip (224) of the inner tube (220) are releasably provided with at least one luer knob (230a or 230b), such that the luer knob (230a or 230b) can be selectively loosened or tightened for negative pressure release in the closed system to allow fluid drop under the gravity.
CENTRIFUGAL-DRIVEN MICROFLUIDIC PLATFORM AND METHOD OF USE THEREOF
In this invention, chromatography is integrated on a centrifugal platform to enable low-cost automated purification. Differing from the traditional chromatography method, purification and separation of a centrifugal compound collecting platform disclosed in the present invention mainly uses a centrifugal force to drive the fluid to flow outward in the radial direction when the motor rotates. The compounds to be separated react with the column packing during the flow, and the compounds with different polarities in the sample are gradually separated. The flow of the fluid can be governed by the motor and the geometry of the fluidic design such that compounds with different characteristics can be separated and collected in different collecting chambers.