A simplified system for air sample collection and analysis for the presence of airborne pathogen is disclosed. An extraction device is used for extracting biomaterial previously deposited on the surface of a capture element of a sampling device, the capture element being of a select cross section and size. The extraction device comprises an upwardly opening head being wider at a top and narrower at a central opening at a bottom. An elongate cavity is attached to the enlarged head at the bottom extending downward from the head and closed at a bottom end to define an interior space, the cavity having a cross section corresponding to the cross section of the capture element and of a slightly larger size than the size of the capture element. An extraction fluid is in the cavity interior space. In use, insertion of the capture element through the head into the elongate cavity extrudes the extraction fluid liquid through the interface between the head and the elongate cavity and provides a fluidic shearing force that serves to solubilize biomaterial from the surface of the capture element.

The invention provides a developer solution vial and methods of its use to diagnose diseases using a sampling and/or assay device, for example, for use with a lateral flow assay (LFA) device. The developer solution vial may include any container that is capable of holding developer solution. The developer solution vial is keyed to the sampling and/or assay device. The developer solution vial minimizes the amount of developer solution required for accurate fluid flow assay testing.

Embodiments in accordance with the present disclosure are directed to configuring an analyzer apparatus for processing a particular sample-processing cartridge. The analyzer apparatus includes a portable container and sample-specific configuration circuitry. The portable container supports and integrates a sample-processing cartridge and the sample-specific configuration circuitry. The sample-specific configuration circuitry identifies configuration information specific to the sample-processing cartridge and configures the analyzer apparatus for a series of state configurations. The configuration can be performed by selecting which of a plurality of biological-sample stimulators to interact with the biological sample, identifying positions in the portable container for each of the selected ones of the plurality of biological-sample stimulators at different times, and while the selected ones of the plurality of biological-sample stimulators are in the identified positions, causing the interactions between the selected ones of the plurality of biological-sample stimulators and the biological sample.

The present disclosure relates to systems and methods for determination of analyte concentrations in solution using materials that are pre-dispensed and dried on conjugate pads or other solid substrates. The solution including the analyte can reconstitute the dried material within a vial to produce a specified concentration of material in the vial. The resulting solution can be used in lateral flow testing.

A diagnostic and prognostic method and system for sequentially analyzing in a biological fluid or tissue extract the presence of an antigenic infectious agent, infectious organism or its toxic product; an antibody response to the antigenic infectious agent, infectious organism or its toxic product; one or more biomarkers formed during infection in response to a communicable disease; and one or more biomarkers to assess the severity of the disease and to monitor the effectiveness of drug therapy or vaccination.

A base assembly for a testing kit comprises: a smart phone holder; a vial holder; and a vial storage area. The base has: a depth sufficient that when a smart phone including a camera is disposed within the smart phone holder, the smart phone is far enough away from a vial held in the vial holder that at least the vial can be imaged by the camera at a known distance and location relative to the camera. The base has a width sufficient that the holder can accommodate the smart phone and that the base can store a vial laid flat on the base during transport. The base has a height sufficient that the smart phone holder can maintain the smart phone upright within the holder, that the vial holder can maintain the vial upright within the vial holder during sample collection and that the base can store a vial laid flat on the base during transport.

Methods and apparatus to mitigate bubble formation in a liquid are disclosed. An example apparatus disclosed herein includes a bottom wall, a first baffle cantilevered from the bottom wall, and a second baffle cantilevered from the bottom wall. The first baffle is spaced apart from the second baffle, and the first baffle and the second baffle are positioned radially relative to an axis of rotation of the apparatus.

A diagnostic and prognostic method and system for sequentially analyzing in a biological fluid or tissue extract the presence of an antigenic infectious agent, infectious organism or its toxic product; an antibody response to the antigenic infectious agent, infectious organism or its toxic product; one or more biomarkers formed during infection in response to a communicable disease; and one or more biomarkers to assess the severity of the disease and to monitor the effectiveness of drug therapy or vaccination.

An analytic plate or other substrate having a permanent etchable, laserable, and/or developable marking surface coating (referred to herein as an “etchable coating” or as a “developable coating”) that is present on at least a portion of any side or surface thereof and is used to deposit a permanent indicium thereon, and a method of using the analytic plate or substrate.

A sampling kit includes firstly a sample tube, which includes a container part for holding a sample and a cap for sealing the container, and secondly a plastic foil instruction sheet. The sheet provides information related to a sample taking process using of the sample tube, which information is printed thereon or is provided in the form of one or more documents held in one or more pockets thereof. The sheet is provided with a support body for holding the sample tube, or at least a container part of the sample tube, during the sampling taking process, the support body and the bottom end of the sample tube being shaped such that they cooperate, to support the sample tube in an upright position.