Diagnostic consumables for use in the analysis of fluid samples, such as whole blood, plasma or urine, are provided. The diagnostic consumables include a substrate having a sample preparation stage that includes an inlet port for receiving a fluid sample, an outlet port for dispensing a prepared fluid sample, and a channel extending from the inlet port to the outlet port. The channel includes an array of micro-projections extending into the channel to define a plurality of flow paths therebetween along at least a portion of a length of the channel between the inlet port and the outlet port. A material is disposed on the array of micro-projections for mixing with the fluid sample as the fluid sample is flowed through the channel to generate the prepared fluid sample. Methods of operating and manufacturing the diagnostic consumables are also provided.

A sample container (1) with a sample-receiving chamber (2) and with a closure piece (3) for closing the sample-receiving chamber (2) in a sealed manner. The sample container (1) has at least two seals (4, 5, 15, 16) arranged separately from each other, and/or the sample-receiving chamber (2) is subdivided into at least two compartments (6) which are thermally decoupled from each other and are connectable by liquid, and/or the sample container (1) has, on an outer wall (7) of the sample-receiving chamber (2), at least one coupling point (8) for the docking of an auxiliary container (9) via a matching counter-coupling point (10) of the auxiliary container (9). The outer wall (7) has at least one predetermined breaking point (11), which is pierced through upon coupling to the auxiliary container (9).

The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.

Proposed are an all-in-one kit for on-site molecular diagnosis and a molecular diagnosis method using the same. The kit includes a first component including a sample pre-processing part, a nucleic acid adsorption part, and a nucleic acid amplification part, and a second component including a detection part. The sample pre-processing part includes a transfer member for transferring a lysis buffer where a nucleic acid is dissolved and functions to pre-processes a sample. The nucleic acid adsorption part is positioned on the sample pre-processing part and is configured to be slidable onto the nucleic acid amplification part. The nucleic acid amplification part is connected to the sample pre-processing part and functions to elute the nucleic acid from the nucleic acid adsorption part and to amplify the eluted nucleic acid. The detection part functions to transfer the nucleic acid amplified by the nucleic acid amplification part and to detect the nucleic acid.

A specimen container has a vessel having a reservoir and a specimen collection region. The specimen container also has a sleeve located within the vessel and moveable in the direction of the reservoir. Movement of the sleeve in the direction of the reservoir results in the specimen collection region and reservoir being brought into fluid communication with each other.

A sample collecting device is provided. The sample collecting device includes a frame, a collect part and a control part. The collect part is disposed in the frame and is provided with a collecting cavity having a collecting port, and the collect part is used to make a sample flow into the collecting cavity from the collecting port. The control part is disposed in the frame, used to make a collecting rod put into a reagent bottle be pulled out and inserted into the collecting cavity to thereby collect the sample, and used to make the collecting rod with the sample be pulled out from the collecting cavity and put back into the reagent bottle. The collecting of sample without manual intervention is realized, effectiveness and consistency of the collected samples are ensured, and the labor cost is reduced.

A disposable cartridge may have a fluid analysis chip for receiving a fluid to be analyzed. The fluid analysis chip may be attached to a fluid preparation unit of the disposable cartridge and may include a base layer. The fluid analysis chip may also include a spacer layer disposed over the base layer, the spacer layer including a microchannel formed therein, the microchannel being configured to guide a flow of the fluid to be analyzed within the fluid analysis chip. The fluid analysis chip may also include a cap layer disposed over the spacer layer, the cap layer including an inlet and an outlet for establishing fluid communication with the microchannel included in the spacer layer, and an interface layer disposed over the cap layer, the interface layer being configured to attach the fluid analysis chip to the fluid preparation unit of the disposable cartridge.

The present invention relates to kits and methods based on lateral flow assay devices for detecting the presence or quantity of one or more test analytes within a test sample taken from the skin of a mammal.

Diagnostic devices for performing diagnostic tests are provided, as well as methods that utilize the diagnostic devices, methods for manufacturing the diagnostic devices, and test kits for performing the diagnostic tests. The diagnostic devices may include a sample chamber; a fluid chamber connected to the sample chamber by a conduit; and a test chamber separated from the sample chamber by a breakable seal. A movable liner may form a portion of an inner surface of the sample chamber. The sample chamber may be configured to receive a sample swab, which may move in a first direction when being inserted in the sample chamber to an inserted position, and which may to move in a second direction to cause the breakable seal to break. Movement of the sample swab in the second direction may cause the liner to move in the second direction to break the breakable seal.

A device and a method for taking up and handling a liquid sample and a substance are described. The device has a sample unit and a substance container. The substance container has a reservoir which is designed to keep a substance in the reservoir. The reservoir also has an opening which is closed by a sealing film or sealing plate so that substance kept in the reservoir is sealed with respect to the surroundings. The sample unit is equipped with a sample taker which is designed to take up and hold a liquid sample. It also has an opener which is designed to be at least partially inserted into the opening of the reservoir and to lift the sealing film or sealing plate from the opening.