A portable skull boiler in accordance with embodiments has a boiler basin optimally sized and configured for effective cleaning of cervid heads, with head positioning means, nose submersion means, and three or more adjustable and removable legs. The basin has one or more lids, and an adjustably positionable heat source. The skull boiler may be disassembled with all components securable in the boiler basin for transport and storage. The basin having a non rectilinear shape that conformingly receives and retains cervid heads thereby minimizing the size and volume of the basin facilitating efficient operation using minimal fuel and water, and easy transport.

The present disclosure relates to a method for manufacturing a microneedle containing a coating part on a needle tip and an apparatus used for the method. When a microneedle is manufactured using the coating method and apparatus according to the present disclosure, a coating part in which a target material is impregnated can be easily inserted into skin and effective dissolution is possible. Further, the target material is allowed to show excellent skin permeability with the dissolution of the coating part of the microneedle manufactured according to the present disclosure, thereby a quantitative amount of target material can be effectively delivered into the skin.

A needle assembly for transdermal administration including a substrate having a first surface and a second surface opposite to the first surface, and fine needles projecting perpendicularly from the first surface. The substrate has grooves on at least one of the first surface and the second surface, and the grooves are formed such that the substrate is deformable following a surface shape of a skin to allow axes of the fine needles to extend in a direction normal to the surface of the skin.

The invention relates to the production of a textured moulding cavity, in particular for the moulding of elastomer parts with surface texturing. This method is based on the acquisition of a texture from a natural model whose surface condition is to be reproduced on an elastomer part by overmoulding the model between two calendered sheets of elastomeric material and vulcanization for a period between 20 minutes and 60 minutes at a temperature between 80 C. and 200 C. The invention also relates to a moulding cavity made of elastomeric material thus obtained and a method for moulding a textured elastomeric part obtained by vulcanization in the cavity of the invention of a sheet of raw calendered elastomeric material on a base element of the same partially vulcanized elastomeric material. Finally, the invention relates to a textured elastomer part obtained with the inventive moulding method.

Novel polymerizable ionic liquid compounds, and polymerizable compositions are described. The compositions comprise an acid functional monomer or acid-functional copolymer (or conjugate base thereof), and an imidazole compound (or conjugate acid thereof). The polymerizable compositions may be cast and cured to form a coating on a substrate, the coating capable of swelling on exposure to water so as to release from that substrate.

Embodiments of the disclosed technology generally include systems and methods for the replication of a vulva. This disclosed method and system provides an option for the creation of an adult pleasure device by replication of the consumer's vulva for use by his, her, or their partner for sexual pleasure in the absence of his, her, or their partner. However, the potential applications of this invention are not limited to such use, and have many uses, such as for a keepsake, an intimate gift, or a fun experience.

An artificial nipple is formed of an elastomeric polymer by use of 3D printing after imaging of a mother's breast in an active state of lactation. The artificial nipple used as an attachment to a baby bottle or as the nipple component of a pacifier. Use of an artificial nipple formed in this manner mitigates a problem with nipple confusion, as may otherwise manifest in newborn offspring.

Provided are a production method of a mold having a recessed pattern in a recessed step portion capable of preventing a liquid from flowing, and a manufacturing method of a pattern sheet.

A production method of a mold having a recessed pattern includes: a plate precursor preparation step of preparing a plate precursor having a pedestal on which a protruding pattern is disposed; a resin plate preparation step of preparing a thermoplastic resin plate having a recessed step portion having a volume equal to or less than a total volume of the protruding pattern and the pedestal; and a resin plate precursor production step of producing a thermoplastic resin plate precursor, the resin plate precursor production step including a positioning step of positioning the protruding pattern of the plate precursor and a center position of the recessed step portion, and a recessed pattern forming step of forming a recessed pattern having an inverted shape of the protruding pattern on the thermoplastic resin plate by pressing the protruding pattern of the heated plate precursor and the pedestal against the recessed step portion, thereafter cooling the plate precursor, and separating the plate precursor from the thermoplastic resin plate.

A laminate nanomold includes a layer of perfluoropolyether defining a cavity that has a predetermined shape and a support layer coupled with the layer of perfluoropolyether. The laminate can also include a tie-layer coupling the layer of perfluoropolyether with the support layer. The tie-layer can also include a photocurable component and a thermal curable component. The cavity can have a broadest dimension of less than 500 nanometers.

An artificial nipple is formed of an elastomeric polymer by use of 3D printing after imaging of a mother's breast in an active state of lactation. The artificial nipple used as an attachment to a baby bottle or as the nipple component of a pacifier. Use of an artificial nipple formed in this manner mitigates a problem with nipple confusion, as may otherwise manifest in newborn offspring.