A needle assembly for transdermal administration including a substrate having a first surface and a second surface opposite to the first surface, and fine needles projecting perpendicularly from the first surface. The substrate has grooves on at least one of the first surface and the second surface, and the grooves are formed such that the substrate is deformable following a surface shape of a skin to allow axes of the fine needles to extend in a direction normal to the surface of the skin.

Provided is a base (1) for a flexible mold, including: a glass sheet (2); a resin sheet (3); and a bonding layer (4) configured to bond the glass sheet (2) and the resin sheet (3) to each other, wherein the resin sheet (3) protrudes from the glass sheet (2).

A method of making a mold, the mold having an interior cavity for containing a first material and a second material, wherein the mold comprises a first port configured to receive the first material, a second port configured to receive the second material, and a first channel for directing the second material to within the first material, the method includes: determining an electronic file having data representing a shape of an ear; processing the electronic file to create an electronic model of the mold, the electronic model of the mold having sprue features; and creating the mold based on the electronic model of the mold.

A replica manufacturing apparatus performs imprint processing of forming a pattern of an imprint material on a replica substrate using a master mold, processes the replica substrate with the formed pattern to manufacture a replica mold, and transfers data of a condition concerning the imprint processing to a management apparatus. An imprint apparatus acquires the data from the management apparatus, and performs the imprint processing of forming a pattern of an imprint material on a substrate using the replica mold.

Methods are disclosed for forming a decorative faceplate for attachment to an ear insert. An impression medium is first inserted into an ear for forming an impression of at least a portion of the ear concha and ear canal. An initial ear insert is formed based on the impression, which insert has an inner portion configured for insertion into the ear canal and an outer portion configured to be disposed in the ear concha and to face outward away from the ear. The outer portion further includes a faceplate attachment area having a perimeter edge that is configured to receive a faceplate. A model of the perimeter edge is generated, and a faceplate is formed from a faceplate material using the model as a guide. A final ear insert is formed, and the faceplate is attached to the faceplate attachment area of the final ear insert.

The invention relates to a reversible microfluidic chip comprising at least one lower part and at least one upper part configured to come into contact with said lower part and to close said chip, said lower part and/or said upper part comprising a microfluidic structure, and said upper part comprising at least one layer of a flexible epoxide polymer material and at least one layer of a rigid epoxide polymer material, at least one part of the flexible layer being directly in physical contact with the lower part of the chip when said chip is in the closed configuration, to the method for the fabrication thereof, to the use of said upper part in a reversible microfluidic chip, to said upper part for producing said chip, and to the uses of said chip in various applications.

A forming method of forming a micropattern which has a direction and a position controlled for each predetermined position on an object subjected to pattern formation, and an imprinting mold producing method, an imprinting mold and an optical device to which such a forming method is applied. A first mask pattern forming process of forming, by imprinting, a first mask pattern for forming the micropattern on a surface of an object subjected to pattern formation, the surface including a region where at least the micropattern is not formed yet; a second mask pattern forming process of forming a resist film on the object subjected to pattern formation and on the first mask pattern, exposing and developing such a film by light emission to form a second mask pattern that causes a region where the micropattern is not formed but the first mask patten is formed to appear in an uncovered manner; and a micropattern forming process of performing etching on the object subjected to pattern formation to form the micropattern. The first mask pattern forming process, the second mask pattern forming process and the micropattern forming process are repeated in this sequence.

A method for providing a replica masturbation device is disclosed. Users upload images of their body parts, and other users use data sets generated based on these images to produce replica masturbation devices of the user's body parts.

The present invention relates to a method for producing a negative skin and a tool. Such a tool can be used, for example, in the automotive industry.

A synthetic polymer film whose surface has a plurality of raised or recessed portions, wherein a two-dimensional size of the plurality of raised or recessed portions is in a range of not less than 0.5 μm and not more than 3 μm when viewed in a normal direction of the synthetic polymer film, the synthetic polymer film has a crosslink structure and contains an organic carboxylic acid, at the lapse of 5 minutes since placing a 200 μL drop of water on the surface of the synthetic polymer film, a pH of an aqueous solution is less than 4, and an area equivalent circle diameter of the aqueous solution is not less than 20 mm, and at the lapse of 60 seconds since placing a drop of water on the surface of the synthetic polymer film, a static contact angle of the water drop with respect to the surface is less than 3°.