A method of manufacturing a tube assembly includes surrounding an outer surface of a cured rubber hose with a thermoplastic layer, the cured rubber hose extending along a length between a first end and a second end and having a first shape along its length, the thermoplastic layer surrounding the cured rubber hose along at least a portion of the length. The cured rubber hose surrounded with the thermoplastic layer is molded into a second shape different than the first shape. The cured rubber hose is retained in the second shape by the thermoplastic layer. A tube assembly includes a cured rubber hose and thermoplastic layer surrounding the rubber hose along at least a portion of the length of the cured rubber hose. The cured rubber hose has been cured in a first shape along its length and the thermoplastic layer retains the cured rubber hose in a second shape.

A method of manufacturing a tube assembly includes surrounding an outer surface of a cured rubber hose with a thermoplastic layer, the cured rubber hose extending along a length between a first end and a second end and having a first shape along its length, the thermoplastic layer surrounding the cured rubber hose along at least a portion of the length. The cured rubber hose surrounded with the thermoplastic layer is molded into a second shape different than the first shape. The cured rubber hose is retained in the second shape by the thermoplastic layer. A tube assembly includes a cured rubber hose and thermoplastic layer surrounding the rubber hose along at least a portion of the length of the cured rubber hose. The cured rubber hose has been cured in a first shape along its length and the thermoplastic layer retains the cured rubber hose in a second shape.

Expandable introducer systems are provided. An expandable introducer system can include an expandable introducer, an expander, a support member, and/or an exchange dilator. The expandable introducer may be configured to transition from an unexpanded configuration to an expanded configuration. For example, the expander may be displaced through the expandable introducer and transition the expandable introducer from the unexpanded configuration to the expanded configuration. The support member may be disposed within the expandable introducer that is in the expanded configuration to maintain the expandable introducer in the expanded configuration.

Expandable introducer systems are provided. An expandable introducer system can include an expandable introducer, an expander, a support member, and/or an exchange dilator. The expandable introducer may be configured to transition from an unexpanded configuration to an expanded configuration. For example, the expander may be displaced through the expandable introducer and transition the expandable introducer from the unexpanded configuration to the expanded configuration. The support member may be disposed within the expandable introducer that is in the expanded configuration to maintain the expandable introducer in the expanded configuration.

The disclosure relates to forming shaped thermoplastic articles having smooth peripheries. Many thermoplastic articles have sharp edges formed upon molding or cutting the article from a feedstock sheet. Such sharp edges can damage thin plastic films or flesh which they contact, and smoothing the edges is desirable. Described herein are methods of forming a smooth periphery for such sharp-edged articles by rolling over the sharp edge. The smoothing operation is performed by forming a deflectable flange including a bend region separated from the potentially sharp peripheral edge by a spacer, deflecting a portion of the deflectable flange, and softening at least one bent portion of the deflectable flange to yield a smooth periphery upon cooling. The deflection can include curling the spacer at or near the peripheral edge. The methods can be performed incrementally and/or in a reciprocating fashion.

The disclosure relates to forming shaped thermoplastic articles having smooth peripheries. Many thermoplastic articles have sharp edges formed upon molding or cutting the article from a feedstock sheet. Such sharp edges can damage thin plastic films or flesh which they contact, and smoothing the edges is desirable. Described herein are methods of forming a smooth periphery for such sharp-edged articles by rolling over the sharp edge. The smoothing operation is performed by forming a deflectable flange including a bend region separated from the potentially sharp peripheral edge by a spacer, deflecting a portion of the deflectable flange, and softening at least one bent portion of the deflectable flange to yield a smooth periphery upon cooling. The deflection can include curling the spacer at or near the peripheral edge. The methods can be performed incrementally and/or in a reciprocating fashion.

A catheter shaft is produced by forming a first polymeric layer onto a flexible inner core while maintaining the inner core in a solid state, and solidifying the first polymeric layer, wherein the solidified first polymeric layer fails to bond with the inner core and is slidable thereon upon flexion of the shaft. A second polymeric layer may be formed over the first polymeric layer, and is slidable thereon when the shaft bends.

A catheter shaft is produced by forming a first polymeric layer onto a flexible inner core while maintaining the inner core in a solid state, and solidifying the first polymeric layer, wherein the solidified first polymeric layer fails to bond with the inner core and is slidable thereon upon flexion of the shaft. A second polymeric layer may be formed over the first polymeric layer, and is slidable thereon when the shaft bends.

A high altitude balloon. A plurality of layers of coextruded extrudate are formed in a seamless sheet in a shape that defines a balloon envelope. Delaminator layers may be interposed between two or more of the layers of extrudate.

In the case of a film (1) from which packaging (2) can be manufactured, in particular for foodstuffs (3), optical glasses (4), individual parts for bioreactors, solar panels or the like, medical devices, pharmaceutical products or the like, the film (1) consists of at least two polymer layers which are joined together in a co-extension die (7) to form the film (1), the film (1) should already have a sterile or at least particle-free surface during the manufacturing process, which surface is reliably protected against contamination of all kinds during the transport and storage times of the film (1). This is achieved in that an additive (8) is present in one of the layers in a dosable amount and/or in that the material pairing between the first and second layers (5.sub.1, 6.sub.1) has a low adhesion force, and in that the first and second layers (5.sub.1, 6.sub.1) can be non-destructively detached from one another in a separating plane (15), in such a way that the film (1) can be divided into two film webs (11, 12).