A guide member including: an upper main body that is positioned so as to enclose the filling valve and so as to be movable in a vertical direction relative to the filling port; and a lower main body that is positioned so as to enclose the upper main body and is configured to be slidable on the surface of the upper main body. The lower main body is provided with an abutting portion that protrudes inward relative to the inner surface of the lower main body and that is configured to abut against at least an opening portion of the container mounted on the container supporting unit, and the guide member is configured to allow the container to be lifted while keeping the abutting portion abutted against the opening portion, thereby guiding the opening portion to an appropriate position relative to the filling port.

A fluid filling apparatus for filling containers with a fluid is provided. An ultrasonic frequency is used to vibrate a filling nozzle between successive container filling cycles. The vibrations break a liquid string filament formed at a discharge end of the filling nozzle at the end of each filling cycle. Methods and a fluid filling nozzle for filling containers with a fluid are also provided.

A fluid filling apparatus for filling containers with a fluid is provided. An ultrasonic frequency is used to vibrate a filling nozzle between successive container filling cycles. The vibrations break a liquid string filament formed at a discharge end of the filling nozzle at the end of each filling cycle. Methods and a fluid filling nozzle for filling containers with a fluid are also provided.

Apparatuses and methods for controlling transfer of substances to a formulation container to provide a predetermined formulation. A controller may utilize one or more of a flow time, flow rate or a volume of transfer of substance. Barcoded and RFID-containing components may be used to determine what connection or disconnection has been made, and/or time thereof. Process compliance may compare measured or determined flow or connection time, flow rate and/or the transfer volume to a predetermined time, flow rate and/or volume, and adjust one or more of the time, flow rate and/or the volume of the transfer. An optional holder or cradle is configured to receive therein a fluid transfer connector formed by the connection of first and second connector portions, each in fluid communication with a flow conduit or channel that delivers substance to or receives substance from its respective connector portion, only if the connector portions are properly connected together. One or more sensors may be used to determine identification information of the connector and/or flow rates of substance through the connector.

Apparatuses and methods for controlling transfer of substances to a formulation container to provide a predetermined formulation. A controller may utilize one or more of a flow time, flow rate or a volume of transfer of substance. Barcoded and RFID-containing components may be used to determine what connection or disconnection has been made, and/or time thereof. Process compliance may compare measured or determined flow or connection time, flow rate and/or the transfer volume to a predetermined time, flow rate and/or volume, and adjust one or more of the time, flow rate and/or the volume of the transfer. An optional holder or cradle is configured to receive therein a fluid transfer connector formed by the connection of first and second connector portions, each in fluid communication with a flow conduit or channel that delivers substance to or receives substance from its respective connector portion, only if the connector portions are properly connected together. One or more sensors may be used to determine identification information of the connector and/or flow rates of substance through the connector.

The present invention provides a filling nozzle obtained by using a resin selected from a cycloolefin polymer and a cycloolefin copolymer, or a filling nozzle including a tubular passage for supplying a pharmaceutical solution, and a filling port disposed at a lower end of the tubular passage, in which the tubular passage and the filling port have a circular peripheral cross-section, and an inner diameter of the passage of the filling port is larger than an inner diameter of the tubular passage disposed on an upstream side.

A manifold port assembly includes a housing bounding a compartment and having an inlet port and a plurality of outlet ports formed thereon and communicating with the compartment. A carousel bounds a plurality of fluid paths that extend therethrough from a corresponding first end to an opposing corresponding second end, at least a portion of each fluid path being spaced apart from the housing and being radially enclosed by the carousel, the carousel being rotatably disposed within the compartment of the housing so that when the first end or the second end of each fluid path is aligned with the inlet port on the housing, the other of the first end or second end of each fluid path is aligned with a corresponding different one of each of the plurality of outlet ports.

A manifold port assembly includes a housing bounding a compartment and having an inlet port and a plurality of outlet ports formed thereon and communicating with the compartment. A carousel bounds a plurality of fluid paths that extend therethrough from a corresponding first end to an opposing corresponding second end, at least a portion of each fluid path being spaced apart from the housing and being radially enclosed by the carousel, the carousel being rotatably disposed within the compartment of the housing so that when the first end or the second end of each fluid path is aligned with the inlet port on the housing, the other of the first end or second end of each fluid path is aligned with a corresponding different one of each of the plurality of outlet ports.

Apparatuses and methods for controlling transfer of substances to a formulation container to provide a predetermined formulation. A controller may utilize one or more of a flow time, flow rate or a volume of transfer of substance. Barcoded and RFID-containing components may be used to determine what connection or disconnection has been made, and/or time thereof. Process compliance may compare measured or determined flow or connection time, flow rate and/or the transfer volume to a predetermined time, flow rate and/or volume, and adjust one or more of the time, flow rate and/or the volume of the transfer. An optional holder or cradle is configured to receive therein a fluid transfer connector formed by the connection of first and second connector portions, each in fluid communication with a flow conduit or channel that delivers substance to or receives substance from its respective connector portion, only if the connector portions are properly connected together. One or more sensors may be used to determine identification information of the connector and/or flow rates of substance through the connector.

Apparatuses and methods for controlling transfer of substances to a formulation container to provide a predetermined formulation. A controller may utilize one or more of a flow time, flow rate or a volume of transfer of substance. Barcoded and RFID-containing components may be used to determine what connection or disconnection has been made, and/or time thereof. Process compliance may compare measured or determined flow or connection time, flow rate and/or the transfer volume to a predetermined time, flow rate and/or volume, and adjust one or more of the time, flow rate and/or the volume of the transfer. An optional holder or cradle is configured to receive therein a fluid transfer connector formed by the connection of first and second connector portions, each in fluid communication with a flow conduit or channel that delivers substance to or receives substance from its respective connector portion, only if the connector portions are properly connected together. One or more sensors may be used to determine identification information of the connector and/or flow rates of substance through the connector.