A pressurised dispensing container (10) comprising a container (11) for product to be dispensed, and a valve fixed to the container, wherein the container contains a propellant comprising 1,1-difluoroethane or a derivative thereof and optionally ethanol.

The valve comprises a valve stem (15), a valve body (16, 18) and one or more seals (20, 21), the valve stem being slidable within the valve body, the one or more seals co-operating with the valve stem for regulating discharge of a fluid. The valve further comprises a sealing gasket (14) for sealing the valve to the dispensing container.

The one or more seals (20, 21) is/are formed from (i) an elastomeric composition, preferably an elastomeric composition comprising an ethylene-propylene-diene terpolymer. The sealing gasket (14) is formed from (ii) an elastomeric composition comprising an isobutylene polymer or co-polymer thereof.

A pressurised dispensing container (10) comprising a container (11) for product to be dispensed, and a valve fixed to the container, wherein the container contains a propellant comprising 1,1-difluoroethane or a derivative thereof and optionally ethanol.

The valve comprises a valve stem (15), a valve body (16, 18) and one or more seals (20, 21), the valve stem being slidable within the valve body, the one or more seals co-operating with the valve stem for regulating discharge of a fluid. The valve further comprises a sealing gasket (14) for sealing the valve to the dispensing container.

The one or more seals (20, 21) is/are formed from (i) an elastomeric composition, preferably an elastomeric composition comprising an ethylene-propylene-diene terpolymer. The sealing gasket (14) is formed from (ii) an elastomeric composition comprising an isobutylene polymer or co-polymer thereof.

An inhaler including a housing having a chamber to receive a valved canister and a stem block, and a mouthpiece in fluid communication with a passage of the stem block; and an actuation mechanism including configured to engage an outer surface of the stem block at a predefined angle relative to the longitudinal axis of the stem block to cause the downward movement of the stem block to activate the valve and release the aerosolizable liquid as the dose of the aerosolized spray out of the mouthpiece of the mechanical inhaler.

An inhaler including a housing having a chamber to receive a valved canister and a stem block, and a mouthpiece in fluid communication with a passage of the stem block; and an actuation mechanism including configured to engage an outer surface of the stem block at a predefined angle relative to the longitudinal axis of the stem block to cause the downward movement of the stem block to activate the valve and release the aerosolizable liquid as the dose of the aerosolized spray out of the mouthpiece of the mechanical inhaler.

Metering valve having a valve body containing a metering chamber defined by a chamber insert and two annular seals, a valve seal and a chamber seal, the chamber insert having a cylindrical wall, an upper edge cooperating with the valve seal and a lower edge cooperating with the chamber seal, a valve sliding axially in the valve body between rest and dispensing positions. The valve is urged towards its rest position by a spring cooperating with the valve body and with the valve. The upper edge of the chamber insert has an annular cutout formed on the radially inner side of the upper edge so that the width of the upper edge in contact with the valve seal is the same, whatever the width of the cylindrical wall. The metering chamber has a variable volume, in particular between 35 and 65 l, defined by the axial dimension of the cutout.

Metering valve having a valve body containing a metering chamber defined by a chamber insert and two annular seals, a valve seal and a chamber seal, the chamber insert having a cylindrical wall, an upper edge cooperating with the valve seal and a lower edge cooperating with the chamber seal, a valve sliding axially in the valve body between rest and dispensing positions. The valve is urged towards its rest position by a spring cooperating with the valve body and with the valve. The upper edge of the chamber insert has an annular cutout formed on the radially inner side of the upper edge so that the width of the upper edge in contact with the valve seal is the same, whatever the width of the cylindrical wall. The metering chamber has a variable volume, in particular between 35 and 65 l, defined by the axial dimension of the cutout.