A filter module for a water treatment apparatus, and a water treatment apparatus comprising the filter module includes: stacked active carbon fiber layers made of active carbon fiber; spacers inserted between the active carbon fiber layers; a pair of current collectors connected to an end of the stacked active carbon fiber layers; and an active carbon fiber filter included stacked one or more active carbon fiber filter units, each active carbon fiber filter unit including a power supply for supplying current to the active carbon fiber layers via the current collectors so that neighboring active carbon fiber layers form cathodes and anodes in alternation. The filter module can lower the hardness of the water while increasing ion removal capability by increasing the specific surface area and water permeability, and can minimize the thickness of the electrodes by eliminating ion exchange membranes and minimizing the volume of current collectors.

The invention provides columns (including pipette tip columns) and automated methods for the purification of nucleic acids including plasmids. Nucleic acids can be purified from unclarified, clarified or partially-clarified cell lysates that contain cell debris. The columns typically include a bed of medium positioned above a bottom frit and with an optional top frit. Plasmid preparation scales include miniprep, midiprep, maxiprep, megaprep and gigaprep.

The present invention relates to a method for conditioning reversed phase SPE cartridges that provides certain advantages compared with known such methods. The method of the invention finds particular use in the automated synthesis of radiolabeled compounds where SPE is used for example in the purification steps.

The present invention relates to the purification of TNFR:Fc fusion protein. More specifically related to process of purification of TNFR:Fc fusion protein wherein the HCP is reduced. The present invention is directed to the use of mixed-mode chromatography and/or affinity chromatography to produce TNFR:Fc fusion protein which is substantially free of at least one of the protein degrading enzyme present in HCP.

The invention relates to a method for chromatographic separation, comprising at least one step of elution of species held on a stationary phase by means of an eluent, followed by a step of moving the eluent in contact with the stationary phase by means of a compressed gas. Preferably, the movement step takes place after a step of elution of the product(s) of interest and/or after a step of regeneration of the stationary phase.

A system, module and method for continuous countercurrent spiral chromatography are disclosed. The module includes an input port for receiving an input solution, a first mixer for mixing the input solution with a recycled solution to produce a first mixed output, a stage I separator for concentrating the first mixed output to produce a stage I solid fraction, a second mixer for mixing the stage I solid fraction from the stage I separator and an optional buffer solution to produce a second mixed output, and a stage II separator for concentrating the second mixed output to produce a stage II solid fraction which exits the module. At least one separator is a spiral separator. The system includes a plurality of modules, and at least one of the plurality of modules includes a spiral separator. The method includes purifying an unpurified solution with the plurality of modules.

In alternative aspects, the invention provides processes for cyclic electrochemical adsorption of aqueous contaminants using nanocomposites of graphene with tin oxide or antimony doped tin oxide.

The present invention relates to a method for purifying a target product in a flow-through chromatography system comprises at least a first column loaded with feed material from a feed source. The at least first column is purged after binding of impurities and wherein the outlet of purged material from the column is subsequently passed to the feed source.

Provided are an apparatus and a method for ion-exchange extraction of lithium from natural or technological brine by using a lithium-selective inorganic sorbent operating on a principle of an ion sieve. The apparatus contains a plurality of ion-exchange columns arranged and interconnected in sequence. Flows of the brine, flush water, acidic desorption solution, and outputs, of the processed products are controlled via switchable shut-off valves. The method can be carried out by operating the apparatus in a parallel or a serial mode of column operations. In the parallel mode, all columns work simultaneously in the same manner. In the serial mode of operation, the columns work individually with a shift of the sorption-flushing-desorption-flushing cycles sequentially and with a transfer of the processed brined sequentially from the first column to the last column and from the last column to the first one thus providing continuity of the lithium-extraction process.

The present disclosure provides processes and systems for ethanol production. In one embodiment, a first beer column receives a first portion of a feed mixture including ethanol and water to form a first beer column bottom stream and a first beer column vaporous overhead stream. A beer column receives a second portion of the feed mixture. A first portion of the first beer column bottom stream is forwarded to a first beer column reboiler. A second portion of the first beer column bottom stream is forwarded to a plurality of evaporators. A condensed portion of the first beer column vaporous overhead stream is forwarded to a stripper column. The stripper column forms a feed stream, which is contacted with a separation system, thereby forming a permeate and a retentate. The permeate is forwarded directly to at least one selected from the first beer column and the stripper column.