A method, device, and system for removing a volatile component from a liquid solution for a chromatographic separation are described. The method includes the flowing of a liquid solution through a first chamber of the device. A volatile component in the liquid solution is transported across a first ion exchange barrier from the first chamber to a second chamber. The first ion exchange barrier has a first charge. The second chamber includes an ion exchange packing having a second charge that is an opposite polarity to the first charge. The volatile component reacts with the ion exchange packing to create a charged component in the second chamber. The charged component having a third charge that is a same polarity to the first charge. The ion exchange packing is regenerated by electrolytically generating a hydronium or a hydroxide.

Methods of maintaining narrow residence time distributions in continuous flow systems, particularly applicable to virus inactivation such as during a protein purification process. Fluid sample is introduced into an axial flow channel and caused to flow therein in discrete packets or zones to minimize residence time distribution and axial dispersion. Embodiments described herein obviate or minimize the need for using large tanks or reservoirs for performing virus inactivation during a protein purification process; reduce the overall time required for virus inactivation, and/or reduce the overall physical space required to perform the virus inactivation operation during a protein purification process, which in turn reduces the overall footprint for the purification process.

A method is disclosed for concentrating and purifying an eluate brine and producing a purified lithium compound. An extraction eluate, rich in lithium, is directed to a nanofiltration unit or a softening process that removes sulfate and/or calcium and magnesium. Permeate from the nanofiltration unit or the effluent from the softening process is directed through an electrodialysis unit. As the lithium-rich solution moves through the electrodialysis unit, lithium, sodium and chloride ions pass from the solution through a cation-transfer membrane and an anion-transfer membrane to concentrate compartments. A dilute stream is directed through the concentrate compartments and collects the lithium, sodium and chloride ions. The electrodialysis unit also produces a product stream which contains non-ionized impurities, such as silica and/or boron. Concentrate from the electrodialysis unit is subject to a precipitation process that produces a lithium compound that is subsequently subjected to a purification process.

Provided is a system and method for producing and purifying biodiesel. In particular, the system comprises a tandem arrangement of at a modular biodiesel reactor and a continuous flow separation and purification unit. The system can further comprise an evaporation unit that is placed between the biodiesel reactor and the continuous flow separation and purification unit.

Rapid, animal protein free, chromatographic processes and systems for obtaining high potency, high yield botulinum neurotoxin for research, therapeutic and cosmetic use.

A method of treating fly ash containing sodium sulfate from a recovery boiler of a chemical pulp mill. This method includes at least the following steps: a) ash is dissolved in an aqueous solution and the pH of the solution is adjusted with alkali for precipitating impurities, b) the solution is filtered for removing the impurities containing precipitate, c) sodium sulfate is crystallized from the solution and the crystals are separated from the solution by filtering or by centrifugation, and d) the crystallized sodium sulfate is used as initial material for producing sodium and sulfur containing chemicals or as process chemical.

The present disclosure provides purification platforms comprising a depth filter step and/or a hydrophobic interaction chromatography (HIC) step and/or a MM-HIC/IEX chromatography step, and are useful for providing a method of reducing a hydrolytic enzyme activity rate of a composition obtained from said purification platforms. Also disclosed herein are methods of using the purification platforms described herein and compositions obtained therefrom, such as pharmaceutical compositions.

Beverage filtration device including a lid body having an internal housing configured to hold an ion exchange resin-filed cartridge therein having a connection end and a top end having an opening therein, and, stem body having a cap region, collar, beverage conduit and stem air tube. The cap region couples to the connection end of the lid body to form a liquid-tight seal coupling there-between. A collar wall first portion fits inside a beverage mouth container and a second portion located outside of the mouth. The beverage conduit spans the collar, a first conduit opening open to the coupling between the cap region and the connection end and a second conduit open to a container interior. The stem body air tube extends through the collar, a proximal opening of the stem body air tube opens to an air vent hole located in the second portion of the collar wall, and, a distal opening of the stem body air tube opens to the container interior.

A solubilized steviol glycoside composition including one or more steviol glycosides and one or more steviol glycoside solubility enhancers can be used as a sweetener composition to sweeten other compositions (sweetenable compositions) such as foods, beverages, medicines, oral hygiene compositions, pharmaceuticals, nutraceuticals, and the like.

Provided is a system and method for producing and purifying biodiesel. In particular, the system comprises a tandem arrangement of at a modular biodiesel reactor and a continuous flow separation and purification unit. The system can further comprise an evaporation unit that is placed between the biodiesel reactor and the continuous flow separation and purification unit.