Described is a mixer for a chromatography system. The mixer includes an inlet manifold channel, an outlet manifold channel and a plurality of transfer channels. The inlet manifold channel has an inlet at a proximal end of the inlet manifold channel for receiving an inlet flow. The transfer channels are fluidly connected between the inlet and outlet manifold channels. The respective fluid connections are distributed along each of the inlet and outlet manifolds channels. The transfer channels have different volumes. The mixer may be formed of a plurality of layer and the layers may be diffusion bonded to each other.

A flow path structure according to an embodiment includes three groups of flow paths connected by branch and merging portions. The first group connects to the second group via a branch portion, and the second group connects to the third group via a merging portion. The branch portion has openings on both the first and second group sides, while the merging portion has openings on both the second and third group sides. If the first group has N flow paths and the second group has M flow paths (where M is N or more), the total opening area of the second group's branch openings is at most M/N times that of the first group's branch openings. Additionally, at least one merging opening in the second group is equal to or smaller than at least one merging opening in the third group.

A static mixer including a first inlet channel, a second inlet channel, and a first dividing wall between the first inlet channel and the second inlet channel. The static mixer further includes a first outlet channel aligned with the first inlet channel along a first axis and a second outlet channel aligned with the second inlet channel along a second axis. The static mixer further includes a fin extending from the dividing wall.

Disclosed cyclonic flow-inducing pumps overcome drawbacks associated with known adverse flow conditions that arise from flow of certain types of materials through a material flow conduit. Such cyclonic flow-inducing pumps provide for flow of flowable material within a flow passage of a material flow conduit (e.g., a portion of a pipeline, tubing or the like) to have a cyclonic flow (i.e., vortex or swirling) profile. Advantageously, the cyclonic flow profile centralizes flow toward the central portion of the flow passage, thereby reducing magnitude of laminar flow. Such cyclonic flow profile provides a variety of other advantages as compared to a parabolic flow profile such as, for example, increased flow rate, reduce inner pipeline wear, more uniform inner pipe wear, reduction in energy consumption, reduced or eliminated adverse considerations such as slugging.

Disclosed cyclonic flow-inducing pumps overcome drawbacks associated with known adverse flow conditions that arise from flow of certain types of materials through a material flow conduit. Such cyclonic flow-inducing pumps provide for flow of flowable material within a flow passage of a material flow conduit (e.g., a portion of a pipeline, tubing or the like) to have a cyclonic flow (i.e., vortex or swirling) profile. Advantageously, the cyclonic flow profile centralizes flow toward the central portion of the flow passage, thereby reducing magnitude of laminar flow. Such cyclonic flow profile provides a variety of other advantages as compared to a parabolic flow profile such as, for example, increased flow rate, reduce inner pipeline wear, more uniform inner pipe wear, reduction in energy consumption, reduced or eliminated adverse considerations such as slugging.

A static mixer includes a mixer housing, a mixing element including mixing bodies arranged one after another along a longitudinal axis so as to be capable of repeated separation and recombination of components, each of the mixing bodies including a first and second inlets, first and second lateral outlets and an intermediate outlet disposed between the first and the second lateral outlet, an input wall separating the first and second inlets, a deflection element arranged downstream of and adjacent to the input wall, first and second output walls arranged downstream of and adjacent to the deflection element, the first output wall separating the first lateral outlet and the intermediate outlet and the second output wall separating the intermediate outlet and the second lateral outlet.

A dilution device may include a first component and a second component. The first component may define a groove including an inlet portion and an outlet portion. The second component may define an inlet in fluid communication with the inlet portion of the first component and an outlet in fluid communication with the outlet portion of the first component. Relative rotation between the first component and the second component may cause relative movement between the outlet and the outlet portion that changes the effective length of the groove fluidly coupling the inlet and the outlet of the second component. The cross-sectional area of the groove may vary along a length of the groove to provide different flow characteristics depending on the effective length of the groove.

Material flow amplifiers overcome drawbacks associated with known adverse flow conditions (e.g., surface erosion and head losses) that arise from flow of certain types of materials (e.g., fluids, slurries, particulates, flowable aggregate, and the like) through a material flow conduit. Such material flow amplifiers provide for flow of flowable material within a flow passage of a material flow conduit (e.g., a portion of a pipeline, tubing or the like) to have a cyclonic flow (i.e., vortex or swirling) profile. Advantageously, the cyclonic flow profile centralizes flow toward the central portion of the flow passage, thereby reducing magnitude of laminar flow. Such cyclonic flow profile provides a variety of other advantages as compared to a parabolic flow profile (e.g., increased flow rate, reduce inner pipeline wear, more uniform inner pipe wear, reduction in energy consumption, reduced or eliminated slugging and the like).

Material flow amplifiers overcome drawbacks associated with known adverse flow conditions (e.g., surface erosion and head losses) that arise from flow of certain types of materials (e.g., fluids, slurries, particulates, flowable aggregate, and the like) through a material flow conduit. Such material flow amplifiers provide for flow of flowable material within a flow passage of a material flow conduit (e.g., a portion of a pipeline, tubing or the like) to have a cyclonic flow (i.e., vortex or swirling) profile. Advantageously, the cyclonic flow profile centralizes flow toward the central portion of the flow passage, thereby reducing magnitude of laminar flow. Such cyclonic flow profile provides a variety of other advantages as compared to a parabolic flow profile (e.g., increased flow rate, reduce inner pipeline wear, more uniform inner pipe wear, reduction in energy consumption, reduced or eliminated slugging and the like).

A static mixer (100), comprising a static mixer housing, having an inlet port (120) for receiving a fluid, a channel (104) in fluid communication with the inlet port (120), a raised rib along a perimeter of the channel (104), a flow splitter for splitting the fluid into a first stream (106a) and a second stream (106b) within channels, a second flow splitter for splitting the first stream (106a) into a third stream (110a) and a fourth stream (110b) within channels and a third flow splitter for splitting the second stream (106b) into a fifth stream (110c) and a sixth stream (110d) within channels, a first T-style junction for rejoining and mixing the third stream and the fourth stream within a channel (112a), a second T-style junction for rejoining and mixing the fifth stream and the sixth stream within a channel (112b), and a third T-style junction for rejoining and mixing the streams; and a plastic film, the plastic film sealed to the raised rib, forming a static mixer (100) capable of mixing the fluid while remaining in a state of laminar flow.