A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.

A manual mixer serves to facilitate mixing and agitating materials for use during surgery. The manual mixer includes a mixing assembly and an actuation assembly for actuating the mixing assembly. The mixing assembly includes at least a paddle portion and a plunger portion. The plunger portion is simultaneously capable of rotational movement with the paddle portion and movement upwardly or downwardly along the paddle portion. Rotation of the paddle portion serves to facilitate mixing and agitating of the materials, and downward movement of the plunger portion serves to facilitate dispensing of the materials from the manual mixer.

Disclosed is a double chamber container. The first chamber comprises a stopper coupled to a first end and a cover coupled to a second end. The second chamber comprises a plunger coupled to one end and an open second end. The first chamber is coupled to the second chamber such that the first end of the first chamber is coupled to the second end of the second chamber.

A specimen container that includes a first cylindrical housing section having a first threaded end, a second threaded end, and a body section formed therebetween, wherein a fill line is placed at a predetermined location on the body section; a threaded winged section that is adapted to be attached to the second threaded end of the first cylindrical housing section, wherein the threaded winged section includes two gripping wings formed on opposite sides of the threaded winged section; a second cylindrical housing section having a first threaded end, a second threaded end, and a body section formed therebetween, wherein two gripping wings are formed on opposite sides of the second cylindrical housing section and are integral therewith; a threaded connector ring that is adapted to connect the first cylindrical housing section to the second cylindrical housing section; and at least one syringe plunger adapted for insertion into the first cylindrical housing section or the second cylindrical housing section.

Mixers for adhesives and sealants that include automatic stroke length adjustment for different sizes and configurations of adhesive and sealant cartridges are disclosed. The mixers include a sensor for detecting when a mixing impeller reaches the top of a cartridge and the bottom of a cartridge, which sends a signal to a main pressure cylinder to reverse direction. The stroke length of the mixer is automatically adjusted without the necessity of manual selection based upon a particular cartridge size.

In some embodiments, a method of making hydrated bone material is provided, the method comprising providing a bone material in a chamber, the bone material comprising a plurality of shaped bone particles or macroparticles, each of the plurality of shaped bone particles or macroparticles having a substantially uniform size, shape and porosity; and mixing each of the plurality of shaped bone particles with liquid in the chamber under pressure so as to cause the liquid to hydrate each of the plurality of shaped bone particles to form uniformly hydrated bone material. In some embodiments, a device for mixing a bone material with a liquid is provided.

A mixer for mixing multi-component materials includes a mixing element and an inlet. The mixing element is arranged at a longitudinal axis of the mixer for mixing multi-component materials. The inlet section is arranged at the longitudinal axis.

A manual mixer serves to facilitate mixing and agitating materials for use during surgery. The manual mixer includes a mixing assembly and an actuation assembly for actuating the mixing assembly. The mixing assembly includes at least a paddle portion and a plunger portion. The plunger portion is simultaneously capable of rotational movement with the paddle portion and movement upwardly or downwardly along the paddle portion. Rotation of the paddle portion serves to facilitate mixing and agitating of the materials, and downward movement of the plunger portion serves to facilitate dispensing of the materials from the manual mixer.

A device for mixing and dispensing bone material is provided. The device comprises a tubular member having an interior surface configured to receive bone material and a fluid to mix the bone material disposed within the tubular member. The tubular member is flexible and has a proximal opening configured to slidably receive a plunger, and a distal opening configured to dispense a mixed bone material from the interior surface of the tubular member. The plunger is less flexible than the tubular member. Methods of mixing and dispensing bone material are also provided.

A static mixer for mixing a multi-component material includes mixing segments arranged one after another along a longitudinal axis. Some of the mixing segments include elongate inlets arranged substantially parallel to one another and elongate outlets arranged parallel to one another, with a respective elongate inlet connected to a respective elongate outlet via a respective passage forming a flow path. The elongate outlets arranged such that an elongate extent is rotated by an angle of rotation of at least 45 about the longitudinal axis with respect to an elongate extent of the elongate inlets, with the elongate outlets being connected to inlets of directly adjacent mixing segments. A blocking element blocks a part of the flow paths between the elongate outlets and the elongate inlets.