A container for bone cement includes a first member defining a chamber, which contains a first ingredient. The chamber also includes a second member movably coupled to the first member. The second member includes a mixing device that is movably disposed within the first chamber, and the second member defines a second chamber containing a second ingredient. The container additional includes an opening device that selectively opens the second chamber and allows the second ingredient to enter from the second chamber into the first chamber. The mixing device is movable within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement. A corresponding method of preparing bone cement is also disclosed.

A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurized canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternatively, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimizing the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.

A bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material for hydration with a liquid is provided, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder on the coherent mass. In some embodiments, a method of implanting a bone material is provided, the method comprising contacting the bone material with a liquid, the bone material comprising a coherent mass of cartridge milled, lyophilized and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass; molding the bone material into a shape to implant the bone material; and implanting the bone material at the target tissue site.

One aspect relates to a method for providing a bone cement from two starting components, having a hollow cylinder-shaped first container, in which a monomer liquid as first starting component can be stored, a hollow cylinder-shaped second container comprising a container wall, a first internal space, and a second internal space, whereby a bone cement powder as second starting component can be stored in the first internal space, and whereby the monomer liquid can be conveyed into the second internal space, a fluid-conducting conveying means arranged between the first internal space and the second internal space, whereby the first container and the second container are axially connected to each other.

A delivery system of a colored product having a target color including an application device of the colored product, at least two reservoirs each containing a respective base product, a calculation module configured to receive the information concerning the target color and to determine a composition of the colored product from the base products contained in the reservoirs, at least one metering device in fluid communication with the reservoirs, configured to deposit on the application device a dose of each of the base products corresponding to the determined composition, a mixing device configured to mix the doses of base products deposited on the application device. Also, a method for delivering a colored product having a target color via the delivery system. Finally, the use of the system for applications requiring the delivery of a colored product having a target color.

A re-mixing dispenser for containing and dispensing a liquid. The dispenser may have one or more tubes, each containing a different liquid. At least one of the liquids may be re-mixed in situ, using a special two-piece plunger and plunger rod. A mixing piece of the two-piece plunger is moveable independently of a top piece and has blades that allow it to move through the liquid. A plunger rod is removably attached to the mixing piece and is operable to move the mixing piece up and down within the tube during mixing. The two plunger pieces are joined and moved as a single plunger during dispensing.

A handheld applicator for delivery of post-treatment coating following application of a conversion coating includes a first vessel extending longitudinally and containing SOCOSURF PACS? solution, a second vessel extending longitudinally and containing hydrogen peroxide, a pH indicator contained in one of the first or second vessels, a mixing region configured to combine the SOCOSURF PACS? solution, hydrogen peroxide, and pH indicator.

A metering and mixing device contains a multichamber cartridge and a cartridge holder having a reception container for the multichamber cartridge and a compressed air connection and a connection for an application device. The reception container has an internal tube arranged coaxially to the walls of the cartridge holder and equipped with static mixing elements. The multichamber cartridge contains an upper portion having a directional valve, a middle portion configured as a tubular empty space surrounded by at least two chambers arranged tubularly in the direction of the longitudinal axis of the cartridge, and a lower portion having a piston for each chamber. The multichamber cartridge is arranged in the cartridge holder such that the inner wall of the inner tube of the multichamber cartridge bears, leak-tight, against the outer wall of the tube of the cartridge holder.

Storage and mixing systems for pasty two-component polymethyl methacrylate bone cements comprise a tubular cartridge having a cylindrical inner chamber, a cartridge head, which closes one end of the tubular cartridge at the front side, a partition that is disposed axially in the cylindrical inner chamber of the cartridge. The partition divides the cylindrical inner chamber of the cartridge bounded by the cartridge head into two cavities that are spatially separated from one another, wherein a first pasty cement component is present in the first cavity and a second pasty cement component is present in the separate second cavity. The systems further comprising two dispensing plungers axially displaceable in the two cavities of the cartridge, wherein the dispensing plungers close the two cavities on the back side of the cavities situated opposite the cartridge head, a bending device for deforming the partition, wherein the bending device is axially movable in the cartridge and is disposed, or is to be disposed, behind the dispensing plungers, as seen from the cartridge head, wherein the bending device has a deflection surface that is inclined with respect to the axis of the cartridge and pushes the partition laterally in the direction of the inside wall of the cartridge when the bending device is pushed into the cartridge.

An entry mixing element is provided for mixing an incoming fluid flow having first and second unmixed components arranged so as to define a transverse flow cross-section perpendicular to a flow direction. The entry mixing element includes a central axis configured to be aligned with the flow direction of the incoming fluid flow, and an entry dividing wall extending parallel to the central axis and positioned to divide the incoming fluid flow into first and second fluid flow portions, each portion containing an amount of the first component and an amount of the second component. The entry dividing wall is configured to divide the incoming fluid flow into the first and second fluid flow portions in any rotational orientation of the entry mixing element about its central axis relative to the transverse flow cross-section of the incoming fluid flow. Related static mixers and methods of mixing are also provided.