A device for providing a bone cement paste from two starting components, comprising a hollow cylindrical cartridge with an interior space, wherein, in a proximal part of the interior space, a bone cement powder is stored as the first starting component, and, in a distal part of the interior space, at least one bag containing a monomer liquid as the second starting component is stored, wherein the interior space is connectible at the proximal part of the interior space to a negative pressure source via a vacuum connector, wherein a dispensing plunger, which is movable axially in the interior space, is arranged between the bone cement powder and the at least one bag, and a feed plunger, which is movable axially in the interior space, is arranged on a side, axially opposite the dispensing plunger.

A continuous chemical process is modified to allow parts thereto to be processed one quantum of matter at a time. This offers precision and efficiency beyond what is possible with the continuous mode. This Quantum Fluid Operation (QFO) is applied to basic unit operations: mixing, reacting, separating.

The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.

A method and device for fabricating vascular networks in for tissue engineering. The vascular network is embedded in a porous scaffold and is created from a sacrificial wax template, according to one embodiment. A extrusion-based three dimensional printer is used to create the template, wherein the printer utilizes an extruder incorporating a mixer to maintain the consistency of the extrudate.

One aspect relates to a method for providing a bone cement from two starting components, having a hollow cylinder-shaped first container, in which a monomer liquid as first starting component can be stored, a hollow cylinder-shaped second container comprising a container wall, a first internal space, and a second internal space, whereby a bone cement powder as second starting component can be stored in the first internal space, and whereby the monomer liquid can be conveyed into the second internal space, a fluid-conducting conveying means arranged between the first internal space and the second internal space, whereby the first container and the second container are axially connected to each other.

A machine for providing a single serving of a cold beverage or frozen confection includes a nest assembly and a lid assembly. The nest assembly defines a recess for receiving a pod containing at least one ingredient for forming a single serving of the cold beverage or frozen confection and at least one helical internal paddle. The nest assembly has a cooling unit operable to cool the nest assembly. The lid assembly includes a lid and a plunger to rotate the at least one helical internal paddle of the pod to dispense the cold beverage or frozen confection forced out of the pod by rotation of the internal paddle. The frozen confection is ejected directly into a container or cone without coming into contact with other portions of the machine.

The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.

The invention relates to a mixer system for producing a cosmetic product. The invention also relates to a bottle for dispensing a cosmetic product. The mixer system is used to produce a cosmetic product from capsules (7, 8, 9) containing the raw materials needed in the composition of such a cosmetic product, namely the cosmetic texturiser, the cosmetic active ingredient and, optionally, a cosmetic fragrance. The invention is intended to be used in the cosmetics industry.

The invention relates to a method for producing a bone cement with a device comprising a cartridge (1) having a cylindrical interior (2), cement powder (6), and monomer liquid (7) in a monomer liquid container (8), a cartridge head (3) having a discharge opening (9), a closure (10) in the discharge opening (9), which closure is permeable to gases and impermeable to powder particles, a drive piston (5), and a central piston (4), wherein the central piston (4) is permeable to gases and the monomer liquid (7) and impermeable to the powder particles of the cement powder (6) and is arranged between the drive piston (5) and the cartridge head (3), wherein the central piston (4) separates the interior (2) into a first cavity (12) and a second cavity (14), the method comprising the following steps:

A) moving the drive piston (5) toward the cartridge head (3),
B) opening the monomer liquid container (8) via the movement of the drive piston (5) and releasing the monomer liquid (7) in the second cavity (14),
C) expelling residual gases into the surroundings of the device by means of the movement of the drive piston (5),
D) injecting the monomer liquid (7) through the central piston (4) into the cement powder (6),
E) displacing gases between the powder particles with the inflowing monomer liquid (7),
F) wetting the powder particles of the cement powder (6), and
G) depressurizing the second cavity (14), wherein the depressurization takes place by partially removing the contained monomer liquid (7).

The invention also relates to such a device for mixing a bone cement, with a depressurization device (16).

The invention relates to a fluid mixing device which mixes a base fluid with one or more additive fluids coming from respective containers, said device being characterised in that it is quick and easy to use and in that no traces are left between uses. The device comprises a first module (1) for extracting at least one first fluid contained in at least one base fluid container (23), a drag, extrusion and discharge mechanism (2), a second module (3) for extracting one or more second fluids or additive fluids from one or more additive containers (24), a mixing tank (4) provided with a hole for the discharge of the final mixture, a battery-powered electronic control board (27), wherein a single stepper motor is used for applying pressure to the base fluid container and the additional fluid container(s), and the drag, extrusion and discharge mechanisms (2) are actuated.