Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.

A method for dosing an injection product into a base product, in particular, for the production of a finishing and/or protective paint product, including the following steps: (a) supply of a mixing device, (b) establishment of a continuous flow of base product, (c) injection of the injection product into the continuous flow for a given time, (d) measurement of the amount of injection product injected, (e) calculation of a desired amount of base product based on the amount of injection product injected, steps (c), (d) and (e) being repeated when the amount of base product having passed since the start of step (c) is equal to the amount of base product desired, the injection product being injected into the base product only during step (c).

A method comprises the steps of receiving a wastewater containing solid particles in suspension, agitating the wastewater for a specified agitation period under specified agitation conditions sufficient to enable auto-flocculation of at least a portion of the solid particles into flocs to provide an agitated wastewater, allowing the agitated wastewater to settle for a specified sedimentation period to allow at least a portion of the flocs to settle, and separating at least a portion of the settled flocs from the agitated wastewater to provide a clarified wastewater effluent.

A cold water saponification method is disclosed. The method is for preferred use in industrial applications such as mining operations wherein saponification of fatty acids is required. Broadly, the method comprises the steps of filling a tank with a solution comprising water, a base and fatty acids, installing a mixer capable of creating a vortex in order to effectively saponify fatty acid particles. The use of a high-shear mixer installed vertically has been proven successful in saponifying fatty acids in cold water.

A method for producing a sealant includes a weighing and mixing step, a kneading step, a stirring and defoaming step, and a filling step. In the weighing and mixing step, a main component and a curing agent are weighed and mixed together. In the kneading step, the mixture mixed in the weighing and mixing step is kneaded. In the stirring and defoaming step, the kneaded product kneaded in the kneading step is stirred and defoamed. In the filling step, the kneaded product defoamed in the stirring and defoaming step is filled into a container. In the stirring and defoaming step, the kneaded product is stirred under a condition wherein a stirring rotational speed at which the kneaded product is stirred and a stirring time for which the kneaded product is stirred are within a range from a product lower limit value to a product upper limit value.

A continuous mixing apparatus for a powder/granular material and a viscous liquid, with a mixing cylinder, a shaft member which is on a central axis of the mixing cylinder and rotates inside the mixing cylinder, and a plurality of mixing paddles disposed on a surface of the shaft member, wherein the mixing cylinder is with a powder/granular material feed port on one end portion, a mixed material discharge port on the other end portion, and a viscous liquid injection unit between the powder/granular material feed port and the mixed material discharge port, and the plurality of mixing paddles are disposed on the shaft member so as to form a spiral around the central axis, the plurality of mixing paddles being, in at least a portion between the viscous liquid injection unit and the mixed material discharge port, attached to provide first rows having an attachment angle of 5 to 60.

A process for operating an oxidizable combustion gas cleaning unit in a metallurgical plant, including the steps of: (a) passing an oxidizable combustion gas from a metallurgical reactor, in particular a blast furnace gas from a blast furnace, in a packed bed scrubber arrangement through a packed bed in countercurrent with a washing water or in a spray scrubber arrangement to remove cyanide compounds, in particular hydrogen cyanide, and to increase the removal of chloride compounds, in particular hydrogen chloride, from the combustion gas by solubilizing the cyanide and chloride compounds in the washing water, (b) collecting the washing water containing solubilized cyanide and chloride compounds at a bottom end of the packed bed or spray scrubber arrangement, and (c) collecting a cleaned oxidizable combustion gas at a top of the packed bed or spray scrubber arrangement, wherein a base is added to the washing water before step (a).

An apparatus for accelerated dissolution of carbonates with buffered pH. The apparatus includes a mixer, a dissolution reactor and a pH correction reactor. The mixer includes: a chamber; a water supply; a carbonic gas supply; and a carbonate supply. Water, carbonic gas and carbonate are provided to the chamber in predetermined continuous flow rates to obtain a design flow rate of lean mixture at the outlet. The dissolution reactor includes a duct connected to the chamber receiving the lean mixture and allowing at least partial dissolution of the carbonate which transforms the lean mixture into an ionic mixture according to the reaction CaCO3+CO2+H2O? Ca(HCO3)2. The pH correction reactor comprises a duct and a hydroxide supply. The mixture is then released into the sea. Embodiments also relate to a method for the accelerated dissolution of carbonates with buffered pH for the permanent sequestration of CO2 in the sea in the form of bicarbonates.

The present invention relates to a method and an arrangement for dissolving starch. Specifically, the present invention relates to a method for dissolving starch by introducing mechanical force to at least partially gelatinized aqueous starch.

Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.