A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.

The present disclosure provides a method for synthesizing fibrous silica nanospheres, the method can include, in sequence, the steps of: a) providing a reaction mixture comprising a silica precursor, a hydrolyzing agent, a template molecule, a cosurfactant and one or more solvents; b) maintaining the reaction mixture under stirring for a length of time; c) heating the reaction mixture to a temperature for a length of time; d) cooling the reaction mixture to obtain a solid, and (e) calcinating the solid to pro duce fibrous silica nanospheres, wherein desirable product characteristics such as particle size, fiber density, surface area, pore volume and pore size can be obtained by controlling one or more parameters of the method. The present disclosure further provides a method for synthesizing fibrous silica nanospheres using conventional heating such as refluxing the reactants in an open reactor, thereby eliminating the need for microwave heating in a closed reactor or the need for any pressure reactors.

Disclosed is an improved process for recovering condensable components from a gas stream, in particular, hydrocarbons from a gas stream such as natural gas. The present process uses solid adsorbent media to remove said hydrocarbons wherein the adsorbent media is regenerated in a continuous fashion in a heated continuous counter-current regeneration system, wherein said heated regenerated adsorbent media is cooled prior to reuse.

Metal-organic framework materials (MOFs) are highly porous entities comprising a multidentate organic ligand coordinated to multiple metal centers, typically as a coordination polymer. Some highly porous MOFs lack stability at ambient conditions. MOFs having ambient condition stability may comprise a plurality of metal clusters (M.sub.4O clusters, M=a metal), and a plurality of 4-(1H-pyrazol-4-yl)benzoate ligands coordinated to the plurality of metal clusters to define an at least partially crystalline network structure having a plurality of internal pores. Methods for synthesizing these MOFs may comprise combining a metal source, such as a preformed metal cluster, with 4-(1H-pyrazol-4-yl)benzoic acid, and reacting the preformed metal cluster with the 4-(1H-pyrazol-4-yl)benzoic acid to form a MOF having an at least partially crystalline network structure with a plurality of internal pores defined therein and comprising a plurality of metal clusters coordinated to a multidentate organic ligand comprising 4-(1H-pyrazol-4-yl)benzoate.

A filter medium is provided with a layer (A) provided with non-impregnated active carbon, a layer (B) with a solid carrier material that is impregnated with a permanganate salt, and a layer (C) with alkaline impregnated active carbon. The layer (B) and the layer (C) are arranged such that a gas flowing through the filter medium flows through the layer (B) before flowing through the layer (C). The layer (A) is arranged such that the gas flowing through the filter medium flows through the layer (A) before flowing through the layer (B) or the gas flowing through the filter medium flows through the layer (A) after flowing through the layer (C).

Compositions containing a porous organic polymer and a heavy metal chelating moiety are provided for binding heavy metals, for example in remediation and purification. The compositions can be stable and recyclable. The compositions can contain heavy metal chelating moieties such as a thiol, a sulfide, an amine, a pyridine, or a combination thereof. The compositions can bind heavy metals such as lead, cadmium, and mercury. The compositions can have a large surface area greater than about 20 m.sup.2/g. The compositions can be used for remediation and purification to remove heavy metals from a solution. The compositions can have a maximum metal uptake capacity of more than 500 mg g.sup.−1 and/or a metal distribution coefficient of at least 1×10.sup.7 mL g.sup.−1 at 1 atm and 296 K. Methods of making the compositions are provided. Methods of binding heavy metals in remediation and purification are also provided.

The present invention is directed to a method of removing uranium from a uranium containing aqueous medium. The method comprises a step of contacting the medium with magnetic mesoporous silica nanoparticles. The nanoparticles comprise mesoporous silica and iron oxide. The nanoparticles may also comprise a functionalized surface obtained by grafting or covalently bonding a functional molecule to the nanoparticle.

The present invention provides a column filler for liquid chromatography that has a great adsorption capacity, adjustable adsorption selectivity, and high shape retainability and therefore is usable for measurement of various substances and capable of achieving excellent separation performance and a high filling rate in a column when used as a column filler for liquid chromatography. Provided is a column filler for liquid chromatography including carbon-coated porous particles, the carbon-coated porous particles including porous particles each having a coating layer containing an amorphous carbon on a surface.

The invention relates to an improved process for preparing metal-organic framework materials, metal-organic frameworks obtainable by such processes, methods using the same, and the use thereof. The process of the invention provides an improved process for preparing metal-organic frameworks in particular monocrystalline metal-organic frameworks having large crystal sizes. The invention also relates to metal organic frameworks comprising iron or titanium, and their uses.

The present disclosure provides novel metal-organic framework materials (MOFs) useful, for example, for gas adsorption, storage, and/or separation. Also provided are methods of making the MOFs, articles of manufacture incorporating the MOFs and methods for making these, as well as methods of using the MOFs.