A novel system for the analysis of molecules and cells, comprising clusters where a non-magnetic particle is supplemented with magnetic particles to form a characteristic pattern, fingerprint or bar code. Methods and devices for formation of such particles are also disclosed.

Disclosed is a device for a solid phase extraction comprising two or more of the sorbents to remove phospholipids and salts from a sample, to thereby eliminate matrix effects during mass spectrometry analysis. In particular, the sorbents includes at least one sorbent which is water-wettable and contains at least one hydrophobic component and at least one hydrophilic component and at least one of sorbent having a specific affinity for a matrix interference like phospholipids. Further disclosed is a method using the device of the present invention.

A method of producing a functionalized material that extracts metal ions from solution, the method comprising: (i) providing a precursor material having nitrile groups appended to its surface; and (ii) reacting said nitrile groups with hydroxylamine or a derivative thereof in the presence of a polar aprotic solvent at a temperature of 60-80° C. for at least 1 hour, to convert at least a portion of said nitrile groups to amidoxime and imide dioxime groups, followed by reaction with a base capable of hydrolyzing any remaining nitrile groups to carboxylic acid groups; wherein said functionalized material has a higher uranium absorption capacity than a functionalized material produced under same conditions except that the nitrile groups are reacted with hydroxylamine in only a protic solvent. The invention is also directed to functionalized materials produced by the above-described method, and methods for using the functionalized material for extracting metal ions from metal-containing solutions.

The present invention relates to an organic-inorganic hybrid nanoporous silica material having high selectivity to particular metal ions, and a method for preparing the same. Specifically, the present invention provides an organic-inorganic hybrid nanoporous silica material and a method for preparing the same, wherein the organic-inorganic hybrid nanoporous silica material has a closed pore form by capturing a functionalized silane compound in a nanoporous silica material, which is surface-modified with a functionalized silane compound, using a cyclic molecule, and enables the sensing and highly selective adsorption of various metals due to the incorporation of an organic ligand capable of adsorbing metal ions in pores.

The present disclosure provides a preparation method of AM-type polystyrene microsphere ofloxacin imprinted polymer as well as an application thereof. A monomer acrylamide and an initiator ammonium persulfate are subjected to graft polymerization on the surface of modified polystyrene primary amine resin, to get grafted particles; then an adsorption test of a levofloxacin solution by the grafted particles PAM/PSA is conducted, and then a levofloxacin surface molecularly imprinted material MIP-PAM/PSA is prepared by using ethylene glycol diglycidyl ether as the crosslinking agent. The present disclosure can realize the separation and purification of racemic ofloxacin effectively, thus providing a new method and material for separating and enriching s-type ofloxacin in the industry. Because the antibacterial efficacy of S-ofloxacin on Gram-negative bacteria and positive bacteria is 8-128 times that of its enantiomer R-ofloxacin, so the present technology can improve the efficacy of a drug greatly.

Functionalized material, methods of producing the functionalized material, and use thereof for separation processes such as for separating and extracting a dissolved organic foulant, charged contaminant or oily matter or any combination thereof from water (e.g., produced water), are provided. The method of making the functionalized material, can include: a) providing a mineral material; b) providing an alkyl chain and/or a perfluorinated species, the alkyl chain or perfluorinated species selected to dissolve organic foulants, charged contaminants or oily matter from water or any combination thereof; c) hydroxylating the material via a concentrated acid solution or a basic solution; and d) grafting the alkyl chain and/or the perfluorinated species onto the material via a silanation reaction.

Provided is a separating agent for optical isomers, which is excellent in solvent resistance and has optical separating ability comparable to or higher than that of existing separating agents for optical isomers of chemical bonding type or physical adsorption type. In the separating agent for optical isomers, amylose (3-chloro-5-methylphenylcarbamate) is supported on a carrier through chemical bonding.

An object of the present invention is to provide a packing material suitable for use as a packing material for size exclusion chromatography for fractionation that requires large-scale treatment, the packing material being capable of being produced by a simple process and reducing column pressure drop even when the particle diameter is small, and is to provide a method for producing the packing material. In the present invention, a packing material for size exclusion chromatography is obtained by a production process including polymerizing glycerol 1,3-dimethacrylate and glycidyl methacrylate in the presence of a polymerization initiator, hydrophilizing the resulting porous particles made of a copolymer using a sugar alcohol, and then opening the rings of remaining glycidyl groups using a mineral acid.

A method of coating at least one silica capillary using a novel dual ligand sol-gel sorbent and method of manufacture of such sorbent is provided herein. The dual ligand sol-gel sorbent provides superior enrichment effects through simultaneous exploitation of superhydrophobicity of one of the ligands and the ability of the other ligand to undergo π-π interaction with hydrophobic aromatic analytes. Sorbent performance is enhanced both in terms of analyte enrichment and sorbent stability, such as pH stability and solvent stability.

Activated carbon, e.g., from waste tires, modified by bimetallic Fe and Ce nanoparticles can provide high surface area and active sites for enhanced dye adsorption. Such nanocomposites can offer magnetic removal from aqueous solutions containing, e.g., Methylene Blue or Rhodamine B. Adsorption equilibrium data fit well to the Langmuir isotherm model, with an adsorption capacity was 324.6 mg/g. Rhodamine B adsorption by such activated carbon-Fe—Ce magnetic adsorbents has an endothermic character and pseudo-second-order kinetics. In ethanol solution, rhodamine B was desorbed at high efficiency and such materials, which could be recycled up to 5 cycles. Such magnetic nanocomposites are adsorbents for treating dyes such as rhodamine B in wastewater, even in large scale adsorption systems. Polyamides can be grafted to such nanocomposites.