Embodiments of the present disclosure provide for Rh(I) catalysts, methods of making alkenyl substituted arenes (e.g., allyl arene, vinyl arene, and the like), methods of making alkyl substituted arenes, and the like.

The current invention describes new metathesis catalysts, a method for their preparation and their use in metathesis reactions.

The present invention relates to an optically pure (+) or () enantiomer of a ruthenium complex having formula (I) as well as the preparation method of said enantiomer, and uses thereof as catalyst, in particular in asymmetric olefin metathesis. ##STR00001##

The present disclosure relates generally to processes for preparing a compound useful in the prevention or treatment of a Retroviridae viral infection, including an infection caused by the human immunodeficiency virus (HIV).

A 4,4-divinylazoarylene-bridged diruthenium catalyst bearing two Ru(CO)(3-methoxypyridin-2-olate)(P.sup.iPr.sub.3).sub.2 moieties, its synthesis, and its use as a catalyst.

The present invention relates to improved synthetic routes of synthesizing adagrasib. The invention also provides intermediates used in the provided synthetic routes.

A 1,4-divinylphenylene-bridged diruthenium complex bearing two Ru(CO)(P.sup.iPr.sub.3).sub.2 moieties with 8-mercaptoquinolato co-ligand, its synthesis, and its use as a catalyst in organic processes.

A method synthesizes at least one 3-halopropyltrihalosilane compound. The method includes I) at least one unsaturated compound selected from the group consisting of allyl halide and methallyl halide; and II) at least one H-silane selected from the group consisting of trihalosilane, methyldihalosilane and dimethylhalosilane. The reaction of the at least one unsaturated compound and the at least one H-silane is carried out in the presence of: III) a Karstedt catalyst and IV) at least one cocatalyst according to formula (A). In formula (A), R.sup.1 is an aryl group; each R.sup.2 is independently an alkyl group; and n is 0 or 1. A catalyst composition suitable for mediating a hydrosilylation reaction. A reactive composition is produced from the reaction products.

A method for producing at least one compound selected from the group consisting of a compound represented by the following formula (10), a compound represented by the following formula (11), a compound represented by the following formula (12), and a compound represented by the following formula (13), which the method containing reacting a compound represented by the following formula (2) with a compound represented by the following formula (7), in the presence of at least one compound selected from the group consisting of a compound represented by the following formula (1), a compound represented by the following formula (3), a compound represented by the following formula (4), a compound represented by the following formula (8), and a compound represented by the following formula (9). ##STR00001##

A palladium(II) complex of formula (1) or a palladium(II) complex of formula (3). ##STR00001##
Also, processes for the preparation of the complexes, and their use in carbon-carbon and carbon-heteroatom coupling reactions.