The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.

A pipeline magnetic separator (10) having a magnet 20 including a length (24) that is to extend transverse of the separator chamber (19) to collect metal from flow passing in the direction (13) through the separator (10). The end surface (26) of the magnet (20) is hemispherical and is transverse of a longitudinal axis (33) of the magnet (20). Upstream of the magnet (20) is a flow diverter (25, 29).

Magnetic assisted separation apparatuses for separating a target substance from a medium in which the target substance is suspended, and related methods, are provided. According to one aspect, a magnetic separator may include a frame having an opening configured to receive one or more containers containing the medium. Additionally, the magnetic separator may include first and second magnetic field generating elements mounted on opposing sides of the frame such that one or more containers can be positioned between the first and second magnetic field generating elements. According to another aspect, a workstation includes a work surface for receiving one or more containers containing the medium, a fluid transfer member, an automated manipulator configured to move the fluid transfer member, and a plurality magnetic field generating elements each being moveable between a position remote from the one or more containers and another position adjacent to the one or more containers.

A system for extracting oxygen from a fluid includes a separator allowing a fluid to pass lengthwise through the separator to produce a mixture with the fluid having at least a portion of oxygen removed from the fluid. The separator includes a wall surrounding an interior portion of a tube. The wall has at least one aperture formed in the wall. The separator also includes at least one magnet positioned adjacently to the at least one aperture. The magnet has a north pole end and a south pole end. A magnetic field gradient is formed between the north pole end and the south pole end, and extends into an interior portion of the tube. The system also includes a storage tank fluidly coupled to the at least one aperture for storing the at least a portion of the oxygen removed from the fluid via the separator.

An inclined magnetic holder comprises a magnetic base and a centrifuge tube support plate. The centrifuge tube support plate has centrifuge tube support holes. The magnetic base comprises a first bottom plate, a fixing plate, and two first-side support plates. Respective top portions of the two first-side support plates are provided with a position-locating slot. Two ends of the centrifuge tube support plate are respectively provided with a position-locating protruding block. The centrifuge tube support holes are evenly and linearly distributed on the centrifuge tube support plate. An elastic circular engagement component for holding a centrifuge tube is provided inside the centrifuge tube support holes. A block magnet is fixed to the fixing plate below and corresponding to each of the centrifuge tube support holes. A north pole or south pole surface of the block magnet faces the centrifuge tube and is parallel to an axis of the centrifuge tube.

Microfluidic systems and methods are described for capturing magnetic target entities bound to one or more magnetic beads. The systems include a well array device that includes a substrate with a surface that has a plurality of wells arranged in one or more arrays on the surface. A first array of wells is arranged adjacent to a first location on the surface. A second and subsequent arrays, if present, are arranged sequentially on the surface at second and subsequent locations. When a liquid sample is added onto the substrate and caused to flow, the liquid sample will flow across the first array first and then flow across the second and subsequent arrays in sequential order. The wells in the first array each have a size that permits entry of only one target entity into the well and each well in the first array has approximately the same size.

A filter for removing ferrous particles from a fluid. The filter has an outer filter housing and a non-ferrous liner inside the housing. A plurality of magnets are longitudinally extended at intervals outside the liner. An insert inside the liner imparting a directional flow to the fluid inside the filter whereby ferrous particles in the fluid are trapped by the magnets and held against the non-ferrous line.

A particle separator including a rotor disposed inside a housing. The rotor has a plurality of magnetic sections that are arranged with alternating poles. A drive rotates the rotor to generate a changing magnetic field. Magnetic particles and non-magnetic conductive particles are removed from a liquid that flows through the particle separator. The magnetic particles attach to the rotor and the non-magnetic conductive particles are repelled away from the rotor by the changing magnetic field.

A method for providing magnetic fluid treatment in which at least one electrical conductor comprising at least one length of an electrical conducting material having a first conductor lead and a second conductor lead is energized. The electrical conductor is coiled with at least one turn to form at least one uninterrupted coil of electrical conductor encircling at least a section of an outer surface of a conduit. Energizing the at least one electrical conductor establishes a magnetic field having lines of flux directed along the flow path and concentrated in a non-magnetically conductive region located between two magnetically conductive regions. A fluid is directed through the conduit past the non-magnetically conductive region to provide magnetic fluid treatment to the fluid.

An automatic purification system using magnetic particles comprises: 1) a first container module; and 2) a system controller module. The first container module comprises a first container and a first magnetic field supply device disposed outside the first container. A first container liquid inlet is formed in the upper portion of the first container, and a first container liquid outlet is formed in the bottom of the first container. The system controller module can generate a variable magnetic field in the first container by controlling the first magnetic field supply device. A method for purifying a target component from a biological sample comprises a step for allowing a biological sample containing a target component to be in contact with magnetic particles capable of specifically binding the target component, in the first container in the automatic purification system. The automatic purification system and method help to efficiently separate a target product from a biological sample, and helps to reduce process costs and time at the same time.