The water-saving nozzle has an outer housing that includes an outer vortex screw in operative engagement with an inner housing that is disposed inside the outer housing. The vortex screw has helical threads. The inner housing has an inner vortex screw with outside helical threads. When water passes through the outer and inner vortex screws the water is rotated before the water passes into the vortex chambers of the inner and outer housings. The water discharged from the outer housing forms an outer dome shape and the water discharged from the inner housing forms an inner dome shape inside the outer dome shape.

The present disclosure provides an apparatus and methods of use for isolating particles. An example apparatus includes (a) a vessel defining a pressurizable chamber, wherein the vessel includes a distal end and a proximal end, (b) an inlet of the pressurizable chamber at the proximal end of the vessel, (c) a nozzle positioned within the pressurizable chamber, wherein the nozzle includes an inlet tube in fluid communication with the inlet of the pressurizable chamber, wherein the nozzle includes an outlet aperture, wherein the nozzle is adjustable to alter a distance between the proximal end of the vessel and the outlet aperture of the nozzle, and wherein the nozzle is adjustable to alter an angle between a longitudinal axis of the vessel and a longitudinal axis of the nozzle, and (d) an outlet of the pressurizable chamber at the distal end of the vessel.

Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm.sup.3 and about 0.15 g/cm.sup.3, and/or a specific surface area (SSA) of at least 18 m.sup.2/g, 20 m.sup.2/g, 25 m.sup.2/g, 30 m.sup.2/g, 32 m.sup.2/g, 34 m.sup.2/g, or 35 m.sup.2/g. Methods for making and using such compositions are also provided.

A spray nozzle comprising a housing including a primary passage defining a primary axis, a series of secondary passages configured to provide swirl to a fluid passing therethrough circumferentially positioned around the housing, a series of standoffs circumferentially spread around an outer surface of the housing and located downstream along the primary axis of the series of swirling passages, wherein each of the swirling passages corresponds to a respective standoff of the series of standoffs, in order to control the swirl of the fluid.

A dispensing head with a staged swirling chamber for a dispensing system includes a spraying nozzle including a dispensing orifice and a swirling chamber opening into the dispensing orifice, the swirling chamber including a converging portion, and extending along an axis between an upstream end and a downstream end in the direction of displacement of the product, and an anvil including a core provided with a peripheral wall, that is housed inside the swirling chamber, and forming with the converging portion at least one fluidic path in which the product circulates, the converging portion including an inner wall of the nozzle, the inner wall and/or the peripheral wall of the core being provided with a plurality of steps, each step being defined by a transverse wall that extends in a plane secant to the axis and a longitudinal wall substantially parallel to the axis, the steps forming obstacles in the fluidic path.

Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm.sup.3 and about 0.15 g/cm.sup.3, and/or a specific surface area (SSA) of at least 18 m.sup.2/g, 20 m.sup.2/g, 25 m.sup.2/g, 30 m.sup.2/g, 32 m.sup.2/g, 34 m.sup.2/g, or 35 m.sup.2/g. Methods for making and using such compositions are also provided.

Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm.sup.3 and about 0.15 g/cm.sup.3, and/or a specific surface area (SSA) of at least 18 m.sup.2/g, 20 m.sup.2/g, 25 m.sup.2/g, 30 m.sup.2/g, 32 m.sup.2/g, 34 m.sup.2/g, or 35 m.sup.2/g. Methods for making and using such compositions are also provided.

Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean bulk density between about 0.050 g/cm.sup.3 and about 0.15 g/cm.sup.3, and/or a specific surface area (SSA) of at least 18 m.sup.2/g, 20 m.sup.2/g, 25 m.sup.2/g, 30 m.sup.2/g, 32 m.sup.2/g, 34 m.sup.2/g, or 35 m.sup.2/g. Methods for making and using such compositions are also provided.

The present disclosure provides an apparatus and methods of use for collecting particles. An example collection device includes (a) a vessel defining a chamber, wherein the vessel includes a distal end and a proximal end, (b) an inlet port extending from the proximal end of the vessel, wherein the inlet port is in fluid communication with the chamber, and (c) an outlet port extending from the proximal end of the vessel, wherein the inlet port is in fluid communication with the chamber, and wherein the outlet port includes a porous material positioned between the chamber and the outlet port.

The water-saving nozzle has an outer housing that includes an outer vortex screw in operative engagement with an inner housing that is disposed inside the outer housing. The vortex screw has helical threads. The inner housing has an inner vortex screw with outside helical threads. When water passes through the outer and inner vortex screws the water is rotated before the water passes into the vortex chambers of the inner and outer housings. The water discharged from the outer housing forms an outer dome shape and the water discharged from the inner housing forms an inner dome shape inside the outer dome shape.