The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a pumping chamber for such an inhalation device. A pumping unit for an inhalation device for medically active liquids for generation of an aerosol comprises a tubular member (1), a check valve (2), and a counter piece, said counter piece being configured to receive at least a downstream segment of said tubular member (1) and having an interior volume, wherein upstream of said tubular member (1), a reservoir (4) can be fluidically connected with said tubular member (1), and downstream of said counter piece, a nozzle unit (6) can be fluidically connected with said counter piece, and wherein the tubular member (1) comprises an upstream section, a downstream section, and the check valve (2) which is positioned between the upstream section and the downstream section, such that a pumping chamber with a pumping chamber volume is defined which comprises the volume of the downstream section of the tubular member (1) and said interior volume of the counter piece, and wherein tubular member (1) and the counter piece can move relatively to one another, such that the pumping chamber volume is variable. The tubular member (1) comprises at least two mechanically distinct parts (1A, 1B), wherein a first part (1A) provides said upstream section, and a second part (1B) provides said downstream section, and the first part (1A) and the second part (1B) are connected to each other such as to form an interface section (1C) serving as a valve chamber (2B) for the valve (2).

The present invention provides for a method for the treatment of a viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises remdesivir or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

A nebulizer for nebulizing a fluid and a reservoir with a fluid are proposed. The reservoir includes a collapsible bag with the fluid, where the bag extends in a circumferential direction within the housing part and wherein the reservoir is manually rotated for tensioning the nebulizer.

A nebulizer and a storage device are provided. The nebulizer includes a casing, an atomization module fixed to the casing, a rotating module rotatably assembled to the casing, a linking module assembled to the rotating module, and a locking module. The linking module is configured to be connected to a bottom of the container bottle, and the starting module is configured to drive the nebulizer by being pushed, thereby enabling liquid in the container bottle to be atomized toward an outside of the nebulizer through the atomization module in an atomization process. The locking module is configured to be connected to a bottom of the container bottle. When the nebulizer completes a predetermined number of times of the atomization process, the locking mechanism is moved toward the casing and is then limited to restrict an operation of the nebulizer. Accordingly, after the nebulizer completes the predetermined number of times of the atomization process, the locking module can restrict rotation of the rotating module for preventing the nebulizer from using the container bottle arranged therein.

A reservoir for a nebulizer includes: a tank or bag containing multiple doses of a fluid to be nebulized, and an indicator device for counting or indicating a number of uses performed or still possible with the reservoir, where at least one of: the reservoir includes a connector for fluidically connecting the tank or bag with the nebulizer, the indicator device is actuated by moving the connector relative to the tank or bag, and the reservoir includes or forms an eccentrical linear guidance for a driving part for driving the indicator device.

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an inhalation device having improved flow characteristics. A inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing (1), inside this housing (1) a reservoir (2) for storing a liquid (F), a pumping device with a hollow cylinder (9) providing a pumping chamber (3) for the generation of a pressure inside said pumping chamber (3), wherein the pumping chamber is fluidically connected with the reservoir (2) via an inlet check valve (4) which blocks in direction of the reservoir (2), a riser pipe (5) which can be received with at least one reservoir-facing, interior end (5A) in said hollow cylinder (9), and a nozzle (6) which is connected liquid-tight to an exterior end (5B) of the riser pipe (5), wherein the volume of the pumping chamber (3) is changeable by means of relative motion of the cylinder (9) to the riser pipe (5), and is characterised in that the riser pipe (5) is immobile and firmly attached to the housing (1) and to the nozzle (6), whereas the hollow cylinder (9) is moveable relative to the housing (1) and to the nozzle (6). The invention also discloses a method for the generation of an aerosol of a medically active liquid (F) by means of an inhalation device.

An apparatus (100) for metered dispensing of a liquid from a container (3) and a spray applicator having the apparatus (100). The apparatus (100) comprises a base body (5) and a nozzle body (16) having an outlet nozzle. The nozzle body (16) is mounted so as to be displaceable relative to the base body (5) from a dispensing to a clamping position. The apparatus (100) comprises a reset spring (14) for moving the nozzle body (16) from the clamping to the dispensing position. The nozzle body (16) and the valve body form a burst chamber (19). By pressure on the trigger mechanism (26), the locking of the valve body (10) is triggered and the spray burst spring (7) presses the valve body (10) in the nozzle direction. A non-return valve is arranged upstream in the valve body. The spray burst chamber is connected to the outlet nozzle.

A reservoir for a nebulizer includes: a tank or bag containing multiple doses of a fluid to be nebulized, and an indicator device for counting or indicating a number of uses performed or still possible with the reservoir, where at least one of: the reservoir includes a connector for fluidically connecting the tank or bag with the nebulizer, the indicator device is actuated by moving the connector relative to the tank or bag, and the reservoir includes or forms an eccentrical linear guidance for a driving part for driving the indicator device.

The disclosure relates to a fluid dispensing device comprising: a housing comprising an orifice and configured to accommodate a portion of a spray delivery device comprising an outlet, a protective cap configured to accommodate the outlet of the spray delivery device and comprising a cap portion, wherein the protective cap is configured for fitting to the housing so that the cap portion covers the orifice, a biasing member transferable between a pre-loaded state and an unloaded state and configured to store energy in the pre-loaded state to produce a discharge of the spray delivery device, a releasable interlock configured to retain the biasing member in the pre-loaded state, a trigger engaged with the interlock and configured to release the interlock when actuated, wherein release of the energy stored in the pre-loaded biasing member is prevented as long as the cap portion covers the orifice.

A device for delivering a predetermined amount of a substance within at least one body cavity of a subject, where the predetermined amount is at an effective amount for treatment of obesity or binge eating disorder. The device includes (a) A volume to contain the predetermined amount of the substance. (b) A delivery end placeable in proximity to the body cavity. The delivery end is in fluid communication with the volume and comprises at least one orifice. (c) A valve mechanically connected to the volume, with at least two configurations: (i) an active configuration configured to deliver the predetermined amount of the substance; and, (ii) an inactive configuration, in which the valve prevents delivery of the predetermined amount of the substance. (d) A fluid tight chamber configured to contain a predetermined volume of pressurized gas at a predetermined pressure.