The present invention provides for a method for the treatment of a viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises remdesivir or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

A nebulizer for nebulizing a liquid from a container is proposed. The nebulizer comprises a liquid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer comprises in addition an air pump for temporarily pressurizing the liquid in the container to help withdrawing the liquid from a collapsible bag in the container.

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a pumping chamber for such an inhalation device. A pumping unit for an inhalation device for medically active liquids for generation of an aerosol comprises a tubular member (1), a check valve (2), and a counter piece, said counter piece being configured to receive at least a downstream segment of said tubular member (1) and having an interior volume, wherein upstream of said tubular member (1), a reservoir (4) can be fluidically connected with said tubular member (1), and downstream of said counter piece, a nozzle unit (6) can be fluidically connected with said counter piece, and wherein the tubular member (1) comprises an upstream section, a downstream section, and the check valve (2) which is positioned between the upstream section and the downstream section, such that a pumping chamber with a pumping chamber volume is defined which comprises the volume of the downstream section of the tubular member (1) and said interior volume of the counter piece, and wherein tubular member (1) and the counter piece can move relatively to one another, such that the pumping chamber volume is variable. The tubular member (1) comprises at least two mechanically distinct parts (1A, 1B), wherein a first part (1A) provides said upstream section, and a second part (1B) provides said downstream section, and the first part (1A) and the second part (1B) are connected to each other such as to form an interface section (1C) serving as a valve chamber (2B) for the valve (2).

An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.

A microstructured passage module for aerosol generator is provided. The module includes a plate overlaid by a cover thus forming a compartment, an entrance for a liquid and an exit. The plate includes a plurality of walls parallel to each other over its entire width so as to define a plurality of passages therebetween. Moreover, a plurality of pillars protruding from the plate are distributed in at least section of the passages. A column is disposed proximate to the exit and blocks a substantial part thereof, leaving longitudinal aisles for the liquid to flow towards the exit. The liquid flows through the compartment from the entrance to the exit such that an aerosol is produced. A distance between two adjacent pillars is D and the longitudinal aisle has a width W. The D and the W are specifically configured such that the aerosol has a predetermined MMAD.

A nebulizer as well as a container with a fluid for such a nebulizer are proposed. The container comprises a control device which indicates initially an unused state of the container before first use. An indicator device stops via a locking device further use of the container in a locked state when a predetermined number of uses has been reached or exceeded. After replacement of the container, the nebulizer can be reset and used again.

An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.

A device is designed to put the inhaler into a triggering-ready state by adding energy to a stored energy source of the inhaler. The inhaler can be inserted into the device and/or mechanically coupled to the device in order to put the inhaler into the triggering-ready state.

A system for testing the proper functioning of an atomiser for dispensing a fluid in the form of an aerosol is proposed, wherein the system comprises the atomiser and a test apparatus, wherein the atomiser comprises a container holding the fluid, and a housing part for inserting and/or replacing the container, wherein the container is movable relative to the housing part in order to dispense the fluid and the test apparatus comprises a measuring device for measuring the movement of the container when the fluid is dispensed. In addition, a method for testing the proper functioning of an atomiser for dispensing a fluid in the form of an aerosol is proposed, wherein the atomiser comprises a container holding the fluid, and a housing part for inserting and/or replacing the container, wherein the container is moved relative to the housing part in order to dispense the fluid and the movement of the container is measured and/or analysed when the fluid is dispensed.

The inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing (1), a reservoir (2), a pumping device with a pumping chamber (3), and a nozzle (6), wherein the interior volume of the pumping chamber (3) is changeable by means of linear relative motion of the pumping chamber to the riser pipe (5). Said linear relative motion can be effected by a relative rotation of a rotatable part (1A) which is part of, or connected to, the housing (1) with respect to a second part (1B) of said housing (1), in that said relative rotation can be transferred by means of a gear mechanism into said relative translational motion. A means for the storage of potential energy (7) is provided which is chargeable by means of said relative rotation, and wherein said energy is releasable to said pumping device when released by activation of a release means. A blocking device is provided which is adapted to block activation of the release means and/or release of the means for the storage of potential energy (7) during rotation of the rotatable part (1A) and/or during loading of the means for the storage of potential energy (7). Also, a method for the prevention of undesired emission of medically active liquid or aerosol from an inhalation device is disclosed.