A method for molding or replicating leather samples for inspection, selecting and later using those samples in applications such as automobile interiors with leather surfaces that are laminated or have a loose grain appearance. In one process variant, the main steps include choosing original samples for replication, the original samples including a characteristic to be replicated; making a replication tool from the approved samples; and producing replicated molded samples with the replication tool that emulate the original samples, thereby enabling the replicated molded samples to be compared with the original sample.

The present invention relates to a method for mould production including: preparing a first core made of polystyrene; shaping the first polystyrene core, thereby obtaining a first shaped core; executing a first thermoforming operation to coat the first shaped core with a first thermoformable thermoplastic material, thereby obtaining a first coated structure.

An imprint apparatus including a stage supporting a stamp master on which a master pattern for forming a stamping pattern on a flexible substrate is formed, or a substrate on which a pattern corresponding to the stamping pattern is formed by contact with the stamping pattern; a roll-to-roll mover to move the flexible substrate along a path adjacent to the stage; a clamp including a front clamp that secures a first portion of the flexible substrate, and a rear clamp that secures a second portion of the flexible substrate spaced apart from the first portion; a pressure roller to press the flexible substrate so that the flexible substrate secured by the clamp is brought into contact with the substrate or the stamp master; and a clamp driving controller to drive the clamp to adjust tension between the first portion and the second portion.

A transdermal drug delivery patch according to an exemplary embodiment of the present invention includes: a flexible base layer; and a plurality of microneedle disposed at one surface of the base layer. Each of the plurality of microneedles includes a biodegradable polymer and a drug and has an empty space inside. Each of the plurality of microneedles is formed as a star-shaped pyramid including a plurality of protrusions extending in a radial direction, and a part between two protrusions adjacent along the circumferential direction among the plurality of protrusions is concave.

A device and method for locally reinforcing and forming an elastic mold for micro-fluidic chips are provided. The device comprises a processing recess provided to a lathe, and a mold master pattern with a clamp installed in the processing recess through the mold master pattern clamp. The cathode of an electrophoresis auxiliary system is connected with a shaft of the lathe, and the output of the electrophoresis auxiliary system is simultaneously connected with the cathode and clamp of the mold master pattern, so that an auxiliary electric field can be formed between the mold master pattern and the cathode, so that a granular colloidal circulation system enables the mixed colloid produced by mixing reinforcing particles and filler colloid to deposit on the region to be reinforced of the elastic mold. A vacuum temperature control system is configured to heat and solidify the mixed colloid formed.

An object is to form a positive electrode active material having small and highly uniform particles by a simple process. A template is formed by forming holes in the template by a nanoimprinting method, and the template is filled with a gel-like LiFePO.sub.4 material, whereby small-sized LiFePO.sub.4 particles are formed and are used as the positive electrode active material of a secondary battery. The particle size can be reduced to less than 50 nm. Further, when the LiFePO.sub.4 particles are sintered, the template may be burned down. By making the particle size of the positive electrode active material smaller than the conventional one, a positive electrode that lithium is injected into and extracted from easily can be manufactured.

The present invention provides a mixture that serves for the preservation of Coleoptera to preserve its exoskeleton and its ornamental appearance; reinforce the exoskeleton of the coleopterous to minimize their fragility; improve the preservation of the insect by making an internal preparation that prevents rupture of the exoskeleton caused by blows, manipulation or pressure on it.

Various embodiments of the present invention relate to plastic surfaces having surface structures and methods of making the same. In various embodiments, the present invention provides a method of forming surface structures on a plastic. The method can include contacting a flowable resin composition to a surface of a metal form including surface structures on the contacted surface thereof, the surface structures having at least one dimension approximately parallel to the metal surface of about 100 nm to about 1 mm, to provide a solid plastic including corresponding surface structures on a surface thereof.

A method for manufacturing microneedle devices and systems and tools for implementing same. The method can include manufacturing a replica mold and forming a microneedle array via the replica mold. The replica mold can be manufactured by disposing replica mold material on a master mold and curing the replica mold material. To reduce manufacturing time, the replica mold material preferably is cured at a high temperature for a relatively short time and then cooled quickly before removal from the master mold. The microneedle array can be formed by disposing microneedle material on the replica mold under vacuum and drying the microneedle material in single or successive disposing and drying operations. One or more optional backing layers can be added to the microneedle array when forming the microneedle device. Advantageously, the disclosed methods, systems and tools can be used to manufacture skin-applied patches for delivering cosmetic and therapeutic agents.

A method for manufacturing microneedle devices and systems and tools for implementing same. The method can include manufacturing a replica mold and forming a microneedle array via the replica mold. The replica mold can be manufactured by disposing replica mold material on a master mold and curing the replica mold material. To reduce manufacturing time, the replica mold material preferably is cured at a high temperature for a relatively short time and then cooled quickly before removal from the master mold. The microneedle array can be formed by disposing microneedle material on the replica mold under vacuum and drying the microneedle material in single or successive disposing and drying operations. One or more optional backing layers can be added to the microneedle array when forming the microneedle device. Advantageously, the disclosed methods, systems and tools can be used to manufacture skin-applied patches for delivering cosmetic and therapeutic agents.