A drug-filled synthetic resin ampule 1m includes an ampule main body 2m and a drug stored in the ampule main body. The ampule main body includes a distal end portion, a hollow portion having a drug storing portion, and an annular breakable portion provided between a lower portion of the distal end portion and an upper portion of the hollow portion. The ampule main body includes no inner lateral surface protrusion on an inner lateral portion thereof which is located on a side toward the distal end portion with respect to the annular breakable portion. The distal end portion is configured such that an inner top surface of the distal end portion is located near a plane defined by the annular breakable portion and an inner surface of the distal end portion is a low-drug-retention surface.

An applicator assembly, a method of assembly of the applicator and a method of use of the applicator. The applicator assembly includes a reservoir body, a neck that extends from the reservoir body and includes an exposable opening at a distal end thereof and a shroud that extends from the distal end about the exposable opening and a cap that is integrally formed with and releasably fixed to the distal end of the neck, fully encompassing the opening in the neck and sealing the reservoir body.

A method for blow-fill-seal (BFS) packaging of a product and a BFS package. The method forms a BFS package with a twist-off top, container body and information panel in a main mold. The container is filled via a fill opening located distal to the twist-off top and the fill opening is sealed with a base portion. This provides a container having a twist-off top that is more reliably secured to the container body. A plurality of containers may be attached to a single information panel. The BFS packaging system may employ a quick change insert to reduce lost production time when changing products or lots. The package includes an information panel integrally formed with a plurality of twist-off tops, each of which is removably attached to a container body whereby each container body can be removed from the package without removing the remaining container bodies from the information panel.

A delaminatable container, including: a container body; and a press-fit cap mounted to the container body. The container body is configured to include a storage portion to store contents and a mouth having an opening to discharge the contents from the storage portion, the storage portion and the mouth having an outer layer and an inner layer, and having an inner bag composed of the inner layer to be shrunk with a decrease in the contents, the mouth includes a mouth-side engagement section provided along an outer circumferential surface of the mouth, the cap includes a cap-side engagement section provided along an inner circumferential surface of the cap, the mouth-side engagement section and the cap-side engagement section are configured to be engageable with each other while the cap is mounted to the mouth.

A fluid container is provided that comprises a body portion configured to at least partially surround fluid. The container also includes a cap portion connected to and above the body portion at a frangible separation site surrounding an opening between the body portion and the cap portion. The cap portion is configured to separate from the body portion at the separation site to expose the opening when a substantially downwardly directed force is applied to a part of the cap portion at a certain radial distance from a longitudinal axis through the opening. The container can include a collar configured to be disposed at least around a part of the body portion. A portion of the collar can be configured to facilitate separation of the cap portion.

Container, including a body having a neck delimiting an opening for the access to a body cavity, and a containment element having at least one deformable side wall located inside the cavity to contain fluid substance, the interior of the containment element sealedly coupled to a collar having a surface resting on the body and a tubular member, extending from the bottom thereof, defining a first passage for the fluid substance in use, an insert housed within the collar, the insert formed of first and second parts, connected by first breakable portion, a shutter sealedly housed, inside the insert, formed of first and second sections, connected by second breakable portion, the second section including a surface, to cooperate, in a sealed manner, with the tubular member when second section is fitted thereon, and a breakable wall which, when broken, permits access to the containment element.

Container, including a body delimiting a cavity to contain fluid substance. A mobile bottom, inside the cavity, sealedly movable along the body internal wall. The body sealedly coupled to a collar having a surface resting on the body and a tubular member extending from the bottom thereof. The tubular member defining a first passage through which the fluid substance flows in use. An insert housed within the collar and formed of first and second parts, connected by a first breakable portion. A shutter housed, in a sealed manner, inside the insert and formed of first and second sections mutually connected by a second breakable portion. The second section including a surface to cooperate, in a sealed manner, with the tubular member when the second section is fitted thereon and a breakable wall which, when broken, permits access to the cavity.

An applicator assembly, a method of assembly of the applicator and a method of use of the applicator. The applicator assembly includes a reservoir body, a neck that extends from the reservoir body and includes an exposable opening at a distal end thereof and a shroud that extends from the distal end about the exposable opening and a cap that is integrally formed with and releasably fixed to the distal end of the neck, fully encompassing the opening in the neck and sealing the reservoir body.

Disclosed is a metal bottle seal that is disposed on the curl of the metal bottle. The bottle seal may be held in place by crimping of the curl. In addition, adhesive may be used to hold the bottle seal on the curl. Adhesives can be used that fill discontinuities that may exist in the curl as a result of substantial drawing and ironing of the metal. Further, the metal bottle seal can be made of a material or laminated with a material that is soft enough to fill the discontinuities. The seal can be preformed as a continuous annulus for easy application to the top of the metal bottle. The metal bottle seal can also be used in conjunction with a cap seal to ensure an adequate and reliable seal.

A container for dispensing a liquid water-insoluble edible fat includes a main body portion containing a body volume and a fill sub-volume, less than the body volume, within a first region of the main body portion. The container includes a pouring portion configured to direct a flow of the liquid water-insoluble edible fat out of the container when the container is tilted off of a vertical axis, and a neck portion connecting the main body portion to the pouring portion. The neck portion has a neck width less than a width of the main body portion in a first direction, the main body volume is configured to further include a catch sub-volume within a second region of the main body portion extending beyond the neck width in the first direction, the second region is different than the first region, and the catch sub-volume is substantially equal to the fill sub-volume.