In accordance with the invention, provided herein are methods for purifying recombinant adeno-associated (rAAV) vector particles.

The disclosure relates to the field of metal ion capture, more particularly of selective capture of nickel Ni(II) ions, by a polymeric compound based on a polymer selected from styrenic polymers and chloropolymers. In the polymeric compound, at least one portion of the monomer units of the polymer is functionalised by the ligand, the ligand including at least one chemical group selected from the glyoxime groups.

The glyoxime groups have a strong affinity for the Ni(II) ions, as well as an excellent selectivity vis-à-vis metal ions of chemical properties similar to Ni(II) ions. This ligand thus allows a selective complexation of the Ni(II) ions by the polymeric compound, including in solutions of low concentrations of Ni(II) ions.

The polymeric compound according to at least one embodiment of the disclosure is particularly intended for capturing the Ni(II) ions during the electrogalvanising methods as well as for recycling material comprising nickel.

Systems and methods use ion exchange to extract lithium from a lithium-containing feed solution such as a salar brine. Lithium ions are loaded into an ion exchange resin and then eluted while recharging the resin. Sodium hydroxide or sodium bicarbonate may be used to recharge the resin but are not directly mixed with the lithium-containing feed solution. An eluate stream is produced containing lithium hydroxide or lithium bicarbonate. Lithium hydroxide can be precipitated as lithium hydroxide or in a hydrate form. Lithium bicarbonate may be converted to lithium carbonate. The system and method optionally includes processing an eluate stream to recover one or more compounds for re-use in regenerating the resin bed.

A method for measuring a proportion of sA1c (%), which includes, when a peak derived from abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C is identified, calculation of the peak area, and measurement of the proportion of sA1c (%) corrected by using the calculation results. Results of measurement are obtained, by cation exchange chromatography, of sA1c (%) with a subject who provided a blood sample containing abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C by eliminating influences by such abnormal hemoglobin.

A method for measuring a proportion of sA1c (%), which includes, when a peak derived from abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C is identified, calculation of the peak area, and measurement of the proportion of sA1c (%) corrected by using the calculation results. Results of measurement are obtained, by cation exchange chromatography, of sA1c (%) with a subject who provided a blood sample containing abnormal hemoglobin D, abnormal hemoglobin S or abnormal hemoglobin C by eliminating influences by such abnormal hemoglobin.

The present invention provides for nutrient extraction and recovery devices that use the Donnan Membrane Principle (DMP) to cause spontaneous separation of dissolved ions along electrochemical potential gradients, wherein anions and cations such as H.sub.2PO.sub.4.sup.−, HPO.sub.4.sup.2−, PO.sub.4.sup.3−, Mg.sup.2+, Ca.sup.2+, NH.sub.4.sup.+, and K.sup.+ are moved from manure containing waste streams through cation and anion exchange membranes into a recovery stream thereby precipitating target compounds including but not limited to struvite, potassium struvite and hydroxyapatite.

Disclosed herein are extraction chromatographic supports comprising a porous support, an inert filler, and metal ion binding extractant that may be used for chromatographic separation of metal ions. Also disclosed herein are methods for preparing and using the extraction chromatographic supports.

In one aspect, separation media are described herein operable for removing one or more water contaminants including NOM and derivatives thereof. Briefly, a separation medium includes a nanoparticle support and an oligomeric stationary phase forming a film on individual nanoparticles of the support, the film having thickness of 1 to 100 nm. In some embodiments, oligomeric chains of the stationary phase are covalently bonded to the individual nanoparticles.

The present invention relates to a method of preparing kestose-containing fructooligosaccharide, and more specifically, a method of preparing kestose-containing fructooligosaccharide having a high content of kestose and excellent storage stability.

Method and system for purifying a sample comprising a biomolecule of interest and impurities, comprising expressing said biomolecule of interest in a bioreactor to form a product sample comprising said biomolecule of interest and impurities; subjecting said product sample to filtration to form a clarified product sample; subjecting said clarified product sample to affinity chromatography to remove impurities; subsequently subjecting said product sample to diafiltration followed by virus filtration and optional concentration. The buffer used during the diafiltration step (and thus in the virus filtration step) is the buffer desired for the final formulation of the product.