A gas generator for gasification of liquids, e.g. vapour from water, including a main rotor body being rotatably mounted to a static support framework to rotate around a rotor body center axle. The main rotor body having main rotor body channels for guiding a flow of a liquid from a rotor body channel inlet towards a rotor body channel outlet located further away from the rotor body center axle than the rotor body channel inlet so liquid in the rotor body channel is forced towards the rotor body channel outlet by centrifugal forces. The main rotor body has cavitator channels connected to the rotor body channel outlet. The cavitator channels have cavitation element to induce a differentiated pressure within the liquid in the cavitator caused by centrifugal forces induced by the rotation of the main rotor body inducing cavitation of the liquid flowing through the cavitator channels.

The invention relates to a mixing device for a primary fluid flow in a first pipe with at least one secondary fluid flow, characterized in that a mixing point of the fluid flows is arranged in each case at the connection of the first pipe to at least one second pipe for the at least one secondary fluid flow, and an orifice plate device for a targeted reduction in the flow cross section is arranged upstream of the mixing point in the at least one second pipe, or the first pipe has a wall section with an orifice plate device for the targeted reduction in the flow cross section, through which orifice plate device the at least one secondary fluid flow flows into the first pipe during operation. The invention furthermore relates to a mixing method and to an aircraft engine.

The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.

The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets; wherein one or both of steps (a) and (b) is performed under microfluidic control; preferably electronic microfluidic control The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.

The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.

This in-line active and reverse calculating mass balance blending system can maintain a chemical at desired control points, such as with respect to concentration, temperature, and/or pressure, while the output flow rate is changing dynamically to a point of use. A blending unit is configured to receive and blend at least two species and deliver a mixture at selected concentrations to points of use. A controller can be configured to determine a mass balance to maintain the concentrations in the mixture using information from metrology systems and a flow in an output to the at least one point of use. The controller also can be configured to maintain a concentration in the mixture within a concentration range by controlling flow rates to the blending unit.

The application relates to microfluidic apparatus and methods of use thereof. Provided in one example is a microfluidic device comprising: a first fluidic input and a second fluidic input; and a fluidic intersection channel to receive fluid from the first fluidic input and the second fluidic input, wherein the fluidic intersection channel opens into a first mixing chamber on an upper region of a first side of the first mixing chamber, wherein the first mixing chamber has a length, a width, and a depth, wherein the depth is greater than about 1.5 times a depth of the fluidic intersection channel; an outlet channel on an upper region of a second side of the first mixing chamber, wherein the outlet channel has a depth that is less than the depth of the first mixing chamber, and wherein an opening of the outlet channel is offset along a width of the second side of the first mixing chamber relative to the fluidic intersection.

Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that retain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed.

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

The present invention relates to multi-bed catalytic reactor with a cylindrical shape comprising a mixing device mounted between two catalyst beds in the reactor, said mixing device comprises connected pipe segments forming mixing section and discharging section.