Contaminate-sequestering coatings including a network of hydrolyzed silane compounds including a plurality of thiol functional groups, a plurality of fluorinated functionalities, or both are provided. The contaminate-sequestering coatings may sequester one or more per- and polyfluoroalkyl substances (PFAS), heavy metals, biological species or any combination thereof. Methods of functionalizing a substrate surface with contaminate-sequestering functionalities that sequester one or more PFAS, heavy metals, or both are also provided. Methods of removing contaminants from contaminate-containing liquids, and devices including the contaminate-sequestering coatings are also provided.

The invention discloses a separation matrix for purification of biomacromolecules, comprising a plurality of particles (1) having a core region (2) and a shell region (3), wherein: a) said shell region is accessible to a target biomacromolecule; b) said core region is less accessible to the target biomacromolecule than the shell region; and c) the core region comprises a grafted polymer comprising residues of at least one polymerizable monomer.

The present disclosure provides a porous silica having an average pore diameter of from 20 to 450 , a median (D50) pore diameter of from 20 to 450 , a pore volume of from 0.15 to 1.2 cm.sup.3 g.sup.1, a surface area of from 100 to 600 m.sup.2 g.sup.1, and a span of 0.80 or less. The present disclosure also provides a method of producing the porous silica. The method includes the step of mixing together an aqueous phase comprising nanoparticulate silica and an organic phase to form a water-in-oil dispersion or emulsion. The organic phase includes an organic solvent that is insoluble or partially soluble in water and optionally also includes a non-polar organic compound that is insoluble in water and at least partially soluble in the organic solvent. A gelling agent is present in the aqueous phase such that the nanoparticulate silica gels form the porous silica.

To provide a chromatography carrier that has excellent antifouling properties and exhibits excellent pressure-resistant performance and shatter-resistant performance.

A chromatography carrier comprising: a polymer having a partial structure containing at least two groups represented by C(O)NH.

The invention discloses a separation matrix which comprises a plurality of separation ligands, defined by the formula R.sub.1-L.sub.1-N(R.sub.3)-L.sub.2-R, immobilized on a support, wherein R.sub.1 is a five- or six-membered, substituted or non-substituted ring structure or a hydroxyethyl or hydroxypropyl group; L.sub.1 is either a methylene group or a covalent bond; R.sub.2 is a five-or six-membered, substituted or non-substituted ring structure; L.sub.2 is either a methylene group or a covalent bond; R.sub.3 is a methyl group; and wherein if R.sub.1 is a hydroxyethyl group and L.sub.1 is a covalent bond, R.sub.2 is a substituted aromatic ring structure or a substituted or non-substituted aliphatic ring structure.

A sorbent useful for CO.sub.2 capture is described, including a solid support with CO.sub.2-sorbing amine and ionic liquid thereon. The ionic liquid is catalytically effective to enhance sorbent characteristics such as (i) CO.sub.2 sorption capacity, (ii) CO.sub.2 sorption rate, (iii) CO.sub.2 desorption capacity, (iv) CO.sub.2 desorption rate, and (v) regeneration temperature, in relation to a corresponding sorbent lacking the ionic liquid. In specific implementations, the sorbent is regenerable at temperatures significantly below 100 C., thereby avoiding the need for steam heat desorption and enabling utilization of waste heat or other low energy thermal regeneration sources.

Methods of passively sampling PFAS in the environment, PFAS sorbents, apparatus and systems (apparatus plus conditions) for sampling groundwater, porewater, and surface water are described.

Porous hybrid inorganic/organic materials comprising ordered domains are disclosed wherein the ordered domains are ordered radially, and having the formula (A).sub.x(B).sub.y(C).sub.z (Formula I) or the formula [A].sub.y[B].sub.x (Formula III), wherein A, B, C, x, y and z in Formula I and A, B, x and y in Formula III are further defined herein, and wherein diffraction peak maxima observed for the material exhibit a 2 position that excludes diffraction peaks resulting from atomic-range order that are associated with amorphous material. Methods of making the materials and use of the materials for chromatographic applications are also disclosed.

The present invention relates to a chromatography ligand defined by the following formula R.sub.1R.sub.2N(R.sub.3)R.sub.4R.sub.5 wherein R.sub.1 is a substituted or non-substituted phenyl group; R.sub.2 is a hydrocarbon chain comprising 0-4 carbon atoms; R.sub.3 is a hydrocarbon chain comprising 1-3 carbon atoms; R.sub.4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R.sub.5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.

The present disclosure relates to a method of separating a compound of interest, particularly unsaturated compound(s) of interest, from a mixture. The compound is separated using a column having a chromatographic stationary phase material for various different modes of chromatography containing a first substituent and a second substituent. The first substituent minimizes compound retention variation over time under chromatographic conditions. The second substituent chromatographically and selectively retains the compound by incorporating one or more aromatic, polyaromatic, heterocyclic aromatic, or polyheterocyclic aromatic hydrocarbon groups, each group being optionally substituted with an aliphatic group. In some examples, the present disclosure can include a chromatographic system having a chromatographic column having a stationary phase with a chromatographic substrate containing silica, metal oxide, an inorganic-organic hybrid material, a group of block copolymers, or a combination thereof.