The present invention relates to a method and to a device for producing solid, at least semisolid dosage forms of pharmaceutical active agents, nutraceutical active agents and/or dietary supplemental active agents, wherein the dosage form is generated in an additive fashion by depositing a building substance in the form of dots.

The present invention relates to a method and to a device for producing solid, at least semisolid dosage forms of pharmaceutical active agents, nutraceutical active agents and/or dietary supplemental active agents, wherein the dosage form is generated in an additive fashion by depositing a building substance in the form of dots.

A solid food has a solid form obtained by compression molding a powder. Where a dissolution process from the solid food starting to dissolve until completely dissolving is measured over time on the basis of electric conductivity, times at which a dissolution ratio where electric conductivity at the time of finish of dissolution is 100%, reaches 20%, 63%, and 95% are t.sub.20, t.sub.63, and t.sub.95, and times (sec) at which the dissolution ratio of a reference solid food, formed under conditions in which a difference in weight with the solid food is within ±0.3%, a difference in surface area is within ±2%, a difference in hardness is within ±4%, and a humidification treatment temperature is 100° C. or lower, reaches 20%, 63%, and 95% are t.sub.20ref, t.sub.63ref, and t.sub.95ref, a solubility index (I.sub.d) represented by the following Formula (1) is less than 1.

I.sub.d=(t.sub.20/t.sub.20ref+t.sub.63/t.sub.63ref+t.sub.95/t.sub.95ref)/3  (1)

An all-in-one beverage serving and a method of manufacturing the all-in-one beverage serving is described. The method includes: forming a mixture of a predetermined amount of panela, a predetermined amount of an active ingredient, optionally a predetermined amount of a functional component, and optionally a predetermined amount of a flavoring component. The method then includes placing the mixture into a mold and compressing the mixture to form a solid tablet (e.g., the all-in-one beverage serving). The solid tablet may then be placed into water or milk (or a similar beverage) to form an instant beverage for a user to enjoy.

An all-in-one beverage serving and a method of manufacturing the all-in-one beverage serving is described. The method includes: forming a mixture of a predetermined amount of panela, a predetermined amount of an active ingredient, optionally a predetermined amount of a functional component, and optionally a predetermined amount of a flavoring component. The method then includes placing the mixture into a mold and compressing the mixture to form a solid tablet (e.g., the all-in-one beverage serving). The solid tablet may then be placed into water or milk (or a similar beverage) to form an instant beverage for a user to enjoy.

The present invention is directed to functional food compositions comprising collagen. In one embodiment, the invention relates to a collagen and nut protein blend, wherein the composition is a solid or semi-solid that is shelf-stable and has a soft texture. The present invention also includes compositions with other nut protein blends, and compositions that further do not contain gluten. A method of making the compositions of the present invention is also claimed.

The present invention is directed to functional food compositions comprising collagen. In one embodiment, the invention relates to a collagen and nut protein blend, wherein the composition is a solid or semi-solid that is shelf-stable and has a soft texture. The present invention also includes compositions with other nut protein blends, and compositions that further do not contain gluten. A method of making the compositions of the present invention is also claimed.

The present invention refers to the use of granules comprising surface-reacted calcium carbonate and one or more binder(s) as excipient in a pharmaceutical, nutraceutical, agricultural, veterinary, cosmetic, home, food, packaging or personal care product, wherein the granules have i) a weight particle size d.sub.90 of 150 to 700 μm, as measured according to mechanical sieving, ii) a weight median particle size d.sub.50 of 45 to 300 μm, as measured according to mechanical sieving, iii) a weight particle size d.sub.10 of 18 to 100 μm, as measured according to mechanical sieving, and iv) a specific surface area of ≥15.0 m.sup.2/g as measured by the BET nitrogen method.

The present invention refers to the use of granules comprising surface-reacted calcium carbonate and one or more binder(s) as excipient in a pharmaceutical, nutraceutical, agricultural, veterinary, cosmetic, home, food, packaging or personal care product, wherein the granules have i) a weight particle size d.sub.90 of 150 to 700 μm, as measured according to mechanical sieving, ii) a weight median particle size d.sub.50 of 45 to 300 μm, as measured according to mechanical sieving, iii) a weight particle size d.sub.10 of 18 to 100 μm, as measured according to mechanical sieving, and iv) a specific surface area of ≥15.0 m.sup.2/g as measured by the BET nitrogen method.

The purpose of the present invention is to provide a new disintegrative particulate composition having an optimal balance between the tablet hardness and disintegrability that are mutually opposing properties, and disintegrating tablets for pharmaceuticals and various kinds of foods comprising said composition.

The present invention relates to a disintegrative particulate composition comprising milled lactose and/or granulated lactose as an excipient, and to a disintegrating tablet for pharmaceuticals or foods, comprising the disintegrative particulate composition, especially the tablet having tablet hardness of from 20 to 200 N, and disintegration time in water of from 1 to 60 sec.